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Using deep learning models to diagnose cancer from histology data presents several challenges. Cancer grading and localization of regions of interest (ROIs) in these images normally relies on both image- and pixel-level labels, the latter…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Jérôme Rony , Soufiane Belharbi , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Syndrome differentiation in Traditional Chinese Medicine (TCM) is the process of understanding and reasoning body condition, which is the essential step and premise of effective treatments. However, due to its complexity and lack of…

Machine Learning · Computer Science 2019-01-23 Zeyuan Wang , Josiah Poon , Shiding Sun , Simon Poon

Precise prognostic stratification of colorectal cancer (CRC) remains a major clinical challenge due to its high heterogeneity. The conventional TNM staging system is inadequate for personalized medicine. We aimed to develop and validate a…

Machine Learning · Computer Science 2025-11-20 Zisong Wang , Xuanyu Wang , Hang Chen , Haizhou Wang , Yuxin Chen , Yihang Xu , Yunhe Yuan , Lihuan Luo , Xitong Ling , Xiaoping Liu

In complex orchard environments, the phenotypic heterogeneity of different apple leaf diseases, characterized by significant variation among lesions, poses a challenge to traditional multi-scale feature fusion methods. These methods only…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Lemin Liu , Fangchao Hu , Honghua Jiang , Yaru Chen , Limin Liu , Yongliang Qiao

Segmentation of focal (localized) brain pathologies such as brain tumors and brain lesions caused by multiple sclerosis and ischemic strokes are necessary for medical diagnosis, surgical planning and disease development as well as other…

Computer Vision and Pattern Recognition · Computer Science 2017-01-25 Mohammad Havaei , Nicolas Guizard , Hugo Larochelle , Pierre-Marc Jodoin

Visualizing the features captured by Convolutional Neural Networks (CNNs) is one of the conventional approaches to interpret the predictions made by these models in numerous image recognition applications. Grad-CAM is a popular solution…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Sam Sattarzadeh , Mahesh Sudhakar , Konstantinos N. Plataniotis , Jongseong Jang , Yeonjeong Jeong , Hyunwoo Kim

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Deep learning models often function as black boxes, providing no straightforward reasoning for their predictions. This is particularly true for computer vision models, which process tensors of pixel values to generate outcomes in tasks such…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Sachin Karmani , Thanushon Sivakaran , Gaurav Prasad , Mehmet Ali , Wenbo Yang , Sheyang Tang

Convolutional Neural Networks (CNNs) have recently been shown to excel at performing visual place recognition under changing appearance and viewpoint. Previously, place recognition has been improved by intelligently selecting relevant…

Robotics · Computer Science 2018-10-31 Stephen Hausler , Adam Jacobson , Michael Milford

Atypical Parkinsonian Disorders (APD), also known as Parkinson-plus syndrome, are a group of neurodegenerative diseases that include progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). In the early stages, overlapping…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Mengyu Li , Ingibjörg Kristjánsdóttir , Thilo van Eimeren , Kathrin Giehl , Lotta M. Ellingsen , the ASAP Neuroimaging Initiative

Methods based on class activation maps (CAM) provide a simple mechanism to interpret predictions of convolutional neural networks by using linear combinations of feature maps as saliency maps. By contrast, masking-based methods optimize a…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Hanwei Zhang , Felipe Torres , Ronan Sicre , Yannis Avrithis , Stephane Ayache

In recent years, convolutional neural networks (CNNs) have achieved significant success in various synthetic aperture radar (SAR) tasks. However, the complexity and opacity of their internal mechanisms hinder the fulfillment of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Siyuan Sun , Yongping Zhang , Hongcheng Zeng , Yamin Wang , Wei Yang , Wanting Yang , Jie Chen

The development of effective treatments for Cerebral Palsy (CP) can begin with the early identification of affected children while they are still in the early stages of the disorder. Pathological issues in the brain can be better diagnosed…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

Unsupervised Anomaly Detection has become a popular method to detect pathologies in medical images as it does not require supervision or labels for training. Most commonly, the anomaly detection model generates a "normal" version of an…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Felix Meissen , Johannes Paetzold , Georgios Kaissis , Daniel Rueckert

Recent brain tumor classification methods often report high accuracy but rely on deep, over-parameterized architectures with limited interpretability, making it difficult to determine whether predictions are driven by tumor-relevant…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Rajan Das Gupta , Md Imrul Hasan Showmick , Lei Wei , Mushfiqur Rahman Abir , Shanjida Akter , Md. Yeasin Rahat , Md. Jakir Hossen

We present a new framework for Patch Distribution Modeling, PaDiM, to concurrently detect and localize anomalies in images in a one-class learning setting. PaDiM makes use of a pretrained convolutional neural network (CNN) for patch…

Computer Vision and Pattern Recognition · Computer Science 2020-11-18 Thomas Defard , Aleksandr Setkov , Angelique Loesch , Romaric Audigier

Automated brain lesions detection is an important and very challenging clinical diagnostic task because the lesions have different sizes, shapes, contrasts, and locations. Deep Learning recently has shown promising progress in many…

Computer Vision and Pattern Recognition · Computer Science 2018-01-08 Mina Rezaei , Haojin Yang , Christoph Meinel

Deep learning techniques have shown great potential in medical image processing, particularly through accurate and reliable image segmentation on magnetic resonance imaging (MRI) scans or computed tomography (CT) scans, which allow the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Yang Liu , Ersi Zhang , Lulu Xu , Chufan Xiao , Xiaoyun Zhong , Lijin Lian , Fang Li , Bin Jiang , Yuhan Dong , Lan Ma , Qiming Huang , Ming Xu , Yongbing Zhang , Dongmei Yu , Chenggang Yan , Peiwu Qin

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Class Activation Mapping (CAM) is a powerful technique used to understand the decision making of Convolutional Neural Network (CNN) in computer vision. Recently, there have been attempts not only to generate better visual explanations, but…

Machine Learning · Computer Science 2021-05-04 Kwang Hee Lee , Chaewon Park , Junghyun Oh , Nojun Kwak
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