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We present PyTorch Connectomics (PyTC), an open-source deep-learning framework for the semantic and instance segmentation of volumetric microscopy images, built upon PyTorch. We demonstrate the effectiveness of PyTC in the field of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-14 Zudi Lin , Donglai Wei , Jeff Lichtman , Hanspeter Pfister

In this paper, we develop novel, efficient 2D encodings for 3D geometry, which enable reconstructing full 3D shapes from a single image at high resolution. The key idea is to pose 3D shape reconstruction as a 2D prediction problem. To that…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Stephan R. Richter , Stefan Roth

We propose a neural network-based approach to topology optimization that aims to reduce the use of support structures in additive manufacturing. Our approach uses a network architecture that allows the simultaneous determination of an…

Machine Learning · Computer Science 2022-10-05 Hongrui Chen , Aditya Joglekar , Kate S. Whitefoot , Levent Burak Kara

Morphology based analysis of cell types has been an area of great interest to the neuroscience community for several decades. Recently, high resolution electron microscopy (EM) datasets of the mouse brain have opened up opportunities for…

Topological methods for data analysis present opportunities for enforcing certain invariances of broad interest in computer vision, including view-point in activity analysis, articulation in shape analysis, and measurement invariance in…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Anirudh Som , Kowshik Thopalli , Karthikeyan Natesan Ramamurthy , Vinay Venkataraman , Ankita Shukla , Pavan Turaga

Neural connectomics has begun producing massive amounts of data, necessitating new analysis methods to discover the biological and computational structure. It has long been assumed that discovering neuron types and their relation to…

Neurons and Cognition · Quantitative Biology 2014-07-17 Eric Jonas , Konrad Kording

Generative models for 3D geometric data arise in many important applications in 3D computer vision and graphics. In this paper, we focus on 3D deformable shapes that share a common topological structure, such as human faces and bodies.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Giorgos Bouritsas , Sergiy Bokhnyak , Stylianos Ploumpis , Michael Bronstein , Stefanos Zafeiriou

In this paper, we study the problem of semantic annotation on 3D models that are represented as shape graphs. A functional view is taken to represent localized information on graphs, so that annotations such as part segment or keypoint are…

Computer Vision and Pattern Recognition · Computer Science 2016-12-05 Li Yi , Hao Su , Xingwen Guo , Leonidas Guibas

We investigate topological descriptors for 3D surface analysis, i.e. the classification of surfaces according to their geometric fine structure. On a dataset of high-resolution 3D surface reconstructions we compute persistence diagrams for…

Computer Vision and Pattern Recognition · Computer Science 2016-01-25 Matthias Zeppelzauer , Bartosz Zieliński , Mateusz Juda , Markus Seidl

A novel 3D shape classification scheme, based on collaborative representation learning, is investigated in this work. A data-driven feature-extraction procedure, taking the form of a simple projection operator, is in the core of our…

Computer Vision and Pattern Recognition · Computer Science 2017-11-21 F. Fotopoulou , S. Oikonomou , A. Papathanasiou , G. Economou , S. Fotopoulos

Motivation: Molecular interaction networks summarize complex biological processes as graphs, whose structure is informative of biological function at multiple scales. Simultaneously, omics technologies measure the variation or activity of…

Quantitative Methods · Quantitative Biology 2020-12-24 Ramin Hasibi , Tom Michoel

Convolutional Neural Network (CNN)-based machine learning systems have made breakthroughs in feature extraction and image recognition tasks in two dimensions (2D). Although there is significant ongoing work to apply CNN technology to…

Computer Vision and Pattern Recognition · Computer Science 2018-02-26 Thomas Corcoran , Rafael Zamora-Resendiz , Xinlian Liu , Silvia Crivelli

This study addresses the challenge of classifying cell shapes from noisy contours, such as those obtained through cell instance segmentation of histological images. We assess the performance of various features for shape classification,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Enrico Grisan

Advances in imaging techniques enable high resolution 3D visualisation of vascular networks over time and reveal abnormal structural features such as twists and loops, and their quantification is an active area of research. Here we showcase…

Unlike other tissue types, like epithelial tissue, which consist of cells with a much more homogeneous structure and function, the nervous tissue spans in a complex multilayer environment whose topographical features display a large…

Biological Physics · Physics 2017-05-12 C. Simitzi , A. Ranella , E. Stratakis

Modern deep neural networks have shown remarkable performance in medical image classification. However, such networks either emphasize pixel-intensity features instead of fundamental anatomical structures (e.g., those encoded by topological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Pengfei Gu , Huimin Li , Haoteng Tang , Dongkuan , Xu , Erik Enriquez , DongChul Kim , Bin Fu , Danny Z. Chen

Mesh models are a promising approach for encoding the structure of 3D objects. Current mesh reconstruction systems predict uniformly distributed vertex locations of a predetermined graph through a series of graph convolutions, leading to…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Edward J. Smith , Scott Fujimoto , Adriana Romero , David Meger

We show dense voxel embeddings learned via deep metric learning can be employed to produce a highly accurate segmentation of neurons from 3D electron microscopy images. A "metric graph" on a set of edges between voxels is constructed from…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Kisuk Lee , Ran Lu , Kyle Luther , H. Sebastian Seung

Shape recognition is the main challenging problem in computer vision. Different approaches and tools are used to solve this problem. Most existing approaches to object recognition are based on pixels. Pixel-based methods are dependent on…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Narges Mirehi , Maryam Tahmasbi , Alireza Tavakoli Targhi

Knowledge Graph Completion has been increasingly adopted as a useful method for helping address several tasks in biomedical research, such as drug repurposing or drug-target identification. To that end, a variety of datasets and Knowledge…

Machine Learning · Computer Science 2025-11-07 Alberto Cattaneo , Stephen Bonner , Thomas Martynec , Edward Morrissey , Carlo Luschi , Ian P Barrett , Daniel Justus