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Luminescence imaging is invaluable for studying biological and material systems, particularly when advanced protocols that exploit temporal dynamics are employed. However, implementing such protocols often requires custom instrumentation,…

Instrumentation and Detectors · Physics 2025-09-16 Ian Coghill , Alienor Lahlou , Andrea Lodetti , Shizue Matsubara , Johann Boucle , Thomas Le Saux , Ludovic Jullien

Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya

LLMs are popular among clinicians for decision-support because of simple text-based interaction. However, their impact on clinicians' performance is ambiguous. Not knowing how clinicians use this new technology and how they compare it to…

Human-Computer Interaction · Computer Science 2026-02-02 Behnam Rahdari , Sameer Shaikh , Jonathan H Chen , Tobias Gerstenberg , Shriti Raj

Since the turn of the millennium, computational modelling of biological systems has evolved remarkably and sees matured use spanning basic and clinical research. While the topic of the peri-millennial debate about the virtues and…

Quantitative Methods · Quantitative Biology 2025-08-05 Axel Loewe , Peter J. Hunter , Peter Kohl

Understanding human behavior is a fundamental goal of social sciences, yet its analysis presents significant challenges. Conventional methodologies employed for the study of behavior, characterized by labor-intensive data collection…

Human-Computer Interaction · Computer Science 2024-07-19 Dominik Schiller , Tobias Hallmen , Daksitha Withanage Don , Elisabeth André , Tobias Baur

We present FabSim, a toolkit developed to simplify a range of computational tasks for researchers in diverse disciplines. FabSim is flexible, adaptable, and allows users to perform a wide range of tasks with ease. It also provides a…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-09-21 Derek Groen , Agastya Bhati , James Suter , James Hetherington , Stefan Zasada , Peter Coveney

Scanning Transmission Electron Microscopy (STEM) coupled with Electron Energy Loss Spectroscopy (EELS) presents a powerful platform for detailed material characterization via rich imaging and spectroscopic data. Modern electron microscopes…

Instrumentation and Detectors · Physics 2024-06-18 Utkarsh Pratiush , Austin Houston , Sergei V Kalinin , Gerd Duscher

Quality patient-provider communication is critical to improve clinical care and patient outcomes. While progress has been made with communication skills training for clinicians, significant gaps exist in how to best monitor, measure, and…

Human-Computer Interaction · Computer Science 2024-07-12 Zhiyuan Wang , Nusayer Hassan , Virginia LeBaron , Tabor E. Flickinger , David Ling , James Edwards , Congyu Wu , Mehdi Boukhechba , Laura E. Barnes

In an effort to overcome the data deluge in computational biology and bioinformatics and to facilitate bioinformatics research in the era of big data, we identify some of the most influential algorithms that have been widely used in the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-03 Faraz Faghri , Sayed Hadi Hashemi , Mohammad Babaeizadeh , Mike A. Nalls , Saurabh Sinha , Roy H. Campbell

Research collaborations are continuously emerging catalyzed by online platforms, where people can share their codes, calculations, data and results. These virtual research platforms are innovative, community oriented, flexible and secure as…

A major challenge in modern radio astronomy is dealing with the massive data volumes generated by wide-bandwidth receivers. Such massive data rates are often too great for a single device to cope, and so processing must be split across…

Instrumentation and Methods for Astrophysics · Physics 2022-02-23 Danny C. Price

Over the past few years, the role of visualization for scientific purpose has grown up enormously. Astronomy makes an extended use of visualization techniques to analyze data, and scientific visualization has became a fundamental part of…

Astrophysics · Physics 2007-05-23 U. Becciani , V. Antonuccio-Delogu , C. Gheller , L. Calori , F. Buonomo , S. Imboden

To harness the potential of advanced computing technologies, efficient (real time) analysis of large amounts of data is as essential as are front-line simulations. In order to optimise this process, experts need to be supported by…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-03 Jovana Knežević , Ralf-Peter Mundani , Ernst Rank

Recently, the impressive performance of large language models (LLMs) on a wide range of tasks has attracted an increasing number of attempts to apply LLMs in drug discovery. However, molecule optimization, a critical task in the drug…

Quantitative Methods · Quantitative Biology 2024-01-22 Geyan Ye , Xibao Cai , Houtim Lai , Xing Wang , Junhong Huang , Longyue Wang , Wei Liu , Xiangxiang Zeng

Observatories are complex scientific and technical institutions serving diverse users and purposes. Their telescopes, instruments, software, and human resources engage in interwoven workflows over a broad range of timescales. These…

Instrumentation and Methods for Astrophysics · Physics 2014-07-30 Robert L. Seaman , W. Thomas Vestrand , Frederic V. Hessman

Advances in molecular technologies underlie an enormous growth in the size of data sets pertaining to biology and biomedicine. These advances parallel those in the deep learning subfield of machine learning. Components in the differentiable…

Quantitative Methods · Quantitative Biology 2024-06-14 Alex Jihun Lee , Reza Abbasi-Asl

Despite the success of large language models (LLMs) on general-purpose tasks, their performance in highly specialized domains such as biomedicine remains unsatisfactory. A key limitation is the inability of LLMs to effectively leverage…

Computation and Language · Computer Science 2026-05-08 Xin Gao , Ruiyi Zhang , Meixi Du , Peijia Qin , Pengtao Xie

Nowadays many telescopes around the world are automated and some networks of robotic telescopes are active or planned as shown by the lists we draw up. Such equipment could be used for the training of students and for science in the…

Astrophysics · Physics 2007-05-23 F. R. Querci , M. Querci

During more than 17 years of operation in space INTEGRAL telescope has accumulated large data set that contains records of hard X-ray and soft gamma-ray astronomical sources. These data can be re-used in the context of multi-wavelength or…

Instrumentation and Methods for Astrophysics · Physics 2021-07-28 A. Neronov , V. Savchenko , A. Tramacere , M. Meharga , C. Ferrigno , S. Paltani

There is a trend in research towards more automation using smart systems powered by artificial intelligence. While experiments are often challenging to automate, they can greatly benefit from automation by reducing labor and increasing…