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We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…

[$^{18}$F]fluorodeoxyglucose (FDG) positron emission tomography (PET) has emerged as a crucial tool in identifying the epileptic focus, especially in cases where magnetic resonance imaging (MRI) diagnosis yields indeterminate results. FDG…

Computer Vision and Pattern Recognition · Computer Science 2024-02-05 Wentao Chen , Jiwei Li , Xichen Xu , Hui Huang , Siyu Yuan , Miao Zhang , Tianming Xu , Jie Luo , Weimin Zhou

Purpose: To develop and evaluate DosimeTron, an agentic AI system for automated patient-specific MC internal radiation dosimetry in PET/CT examinations. Materials and Methods: In this retrospective study, DosimeTron was evaluated on a…

Medical Physics · Physics 2026-04-09 Eleftherios Tzanis , Michail E. Klontzas , Antonios Tzortzakakis

A novel FPGA based online tracking algorithm for helix track reconstruction in a solenoidal field, developed for the PANDA spectrometer, is described. Employing the Straw Tube Tracker detector with 4636 straw tubes, the algorithm includes a…

Instrumentation and Detectors · Physics 2017-08-02 Yutie Liang , Hua Ye , Martin J Galuska , Thomas Gessler , Wolfgang Kühn , Jens Sören Lange , Milan N Wagner , Zhen'an Liu , Jingzhou Zhao

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Subject motion in whole-body dynamic PET introduces inter-frame mismatch and seriously impacts parametric imaging. Traditional non-rigid registration methods are generally computationally intense and time-consuming. Deep learning approaches…

Image and Video Processing · Electrical Eng. & Systems 2022-06-29 Xueqi Guo , Bo Zhou , David Pigg , Bruce Spottiswoode , Michael E. Casey , Chi Liu , Nicha C. Dvornek

The success of large-scale pre-trained models has established fine-tuning as a standard method for achieving significant improvements in downstream tasks. However, fine-tuning the entire parameter set of a pre-trained model is costly.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Yijin Huang , Pujin Cheng , Roger Tam , Xiaoying Tang

We study the potential of the MCP-PMT read-out to detect single photo-electron using transmission lines. Such a solution limits the number of read-out channels, has a uniform time resolution across the PMT surface and provides…

Instrumentation and Detectors · Physics 2022-01-26 M. Follin , R. Chyzh , C. -H. Sung , D. Breton , J. Maalmi , T. Chaminade , E. Delagnes , K. Schäfers , C. Weinheimer , D. Yvon , V. Sharyy

Positron Emission Tomography (PET) is an imaging technique which can be used to investigate chemical changes in human biological processes such as cancer development or neurochemical reactions. Most dynamic PET scans are currently analyzed…

Applications · Statistics 2014-11-11 Ci-Ren Jiang , John A D Aston , Jane-Ling Wang

Improving the coincidence time resolution (CTR) of time-of-flight positron emission tomography (TOF-PET) systems to achieve a higher signal-to-noise ratio (SNR) gain or even direct positron emission imaging (dPEI) is of paramount importance…

Visual tracking is one of the most important application areas of computer vision. At present, most algorithms are mainly implemented on PCs, and it is difficult to ensure real-time performance when applied in the real scenario. In order to…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Ke Song , Chun Yuan , Peng Gao , Yunxu Sun

Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

In this study, we propose a fast implementation of a Maximum Likelihood Positioning (MLP) algorithm to estimate the energy and identify the active scintillator pixel in staggered layer scintillation detectors for PET. The staggered layer…

Resting state functional MRI (rs-fMRI) is a widespread and powerful tool for investigating functional connectivity and brain disorders. However, functional connectivity analysis can be seriously affected by random and structured noise from…

Neurons and Cognition · Quantitative Biology 2021-04-01 Yujian Diao , Ting Yin , Rolf Gruetter , Ileana O. Jelescu

To correct for respiratory motion in PET imaging, an interpretable and unsupervised deep learning technique, FlowNet-PET, was constructed. The network was trained to predict the optical flow between two PET frames from different breathing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Teaghan O'Briain , Carlos Uribe , Kwang Moo Yi , Jonas Teuwen , Ioannis Sechopoulos , Magdalena Bazalova-Carter

High particle rates in current and future experiments make pile-up phenomena a critical issue for extracting useful information. In this context, timing can be important as the 4$^{\mathrm{th}}$ dimension parameter for triggering or event…

Instrumentation and Detectors · Physics 2025-12-05 A. Kallitsopoulou , I. Maniatis , I. Manthos , T. Papaevangelou , L. Sohl , A. Tsiamis , S. E. Tzamarias

Current clinical PET systems utilize detectors where the scintillator typically contains single elements of 3 - 6 mm width and about 20 mm height. While providing good TOF performance, this design limits the spatial resolution and causes…

Instrumentation and Detectors · Physics 2022-11-17 Florian Mueller , Stephan Naunheim , Yannick Kuhl , David Schug , Torsten Solf , Volkmar Schulz

To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yuchen Fei , Yanmei Luo , Yan Wang , Jiaqi Cui , Yuanyuan Xu , Jiliu Zhou , Dinggang Shen

The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…

Instrumentation and Detectors · Physics 2016-10-12 J. J Gomez-Cadenas , J. M. Benlloch-Rodríguez , P. Ferrario , F. Monrabal , J. Rodríguez , J. F. Toledo

Dynamic FDG PET imaging study of n = 52 rats including 26 control Wistar-Kyoto (WKY) rats and 26 experimental spontaneously hypertensive rats (SHR) were performed using a Siemens microPET and Albira trimodal scanner longitudinally at 1, 2,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Shubhrangshu Debsarkar , Bijoy Kundu
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