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This work introduces ParAMS -- a versatile Python package that aims to make parameterization workflows in computational chemistry and physics more accessible, transparent and reproducible. We demonstrate how ParAMS facilitates the parameter…

Chemical Physics · Physics 2021-05-18 Leonid Komissarov , Robert Rüger , Matti Hellström , Toon Verstraelen

We present a novel method for predicting binary phase diagrams through the automatic construction of a minimal basis set of representative templates. The core assumption is that any materials space can be divided into a small number of…

Materials Science · Physics 2024-10-03 Caja Annweiler , Simone Di Cataldo , Maurits W. Haverkort , Lilia Boeri

Microarray technology is still an important way to assess gene expression in molecular biology, mainly because it measures expression profiles for thousands of genes simultaneously, what makes this technology a good option for some studies…

Computation · Statistics 2015-11-12 Gustavo H. Esteves , Roberto Hirata

Atomic-level modeling performed at large scales enables the investigation of mesoscale materials properties with atom-by-atom resolution. The spatial complexity of such cross-scale simulations renders them unsuitable for simple human visual…

Materials Science · Physics 2022-04-05 Heejung Chung , Rodrigo Freitas , Gowoon Cheon , Evan J. Reed

Generative models for materials have achieved strong performance on periodic bulk crystals, yet their ability to generalize across scale transitions to finite nanostructures remains largely untested. We introduce Crystal-to-Nanoparticle…

Materials Science · Physics 2026-01-28 Can Polat , Erchin Serpedin , Mustafa Kurban , Hasan Kurban

The availability of rich 3D datasets corresponding to the geometrical complexity of the built environments is considered an ongoing challenge for 3D deep learning methodologies. To address this challenge, we introduce GenScan, a generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Mohammad Keshavarzi , Oladapo Afolabi , Luisa Caldas , Allen Y. Yang , Avideh Zakhor

Deep learning based generative models such as deepfake have been able to generate amazing images and videos. However, these models may need significant transformation when applied to generate crystal materials structures in which the…

Materials Science · Physics 2021-12-15 Yong Zhao , Edirisuriya MD Siriwardane , Jianjun Hu

Conventionally, high-throughput computational materials searches start from an input set of bulk compounds extracted from material databases, and this set is screened for candidate materials for specific applications. In contrast, many…

Materials Science · Physics 2023-04-11 Rachel Woods-Robinson , Matthew K. Horton , Kristin A. Persson

Polymers play a crucial role in the development of engineering materials, with applications ranging from mechanical to biomedical fields. However, the limited polymerization processes constrain the variety of organic building blocks that…

Soft Condensed Matter · Physics 2024-12-13 Debasish Mohanty , V Shreyas , Akshaya Palai , Bharath Ramsundar

We present McGenus, an algorithm to predict RNA secondary structures with pseudoknots. The method is based on a classification of RNA structures according to their topological genus. McGenus can treat sequences of up to 1000 bases and…

Biomolecules · Quantitative Biology 2013-02-18 M. Bon , C. Micheletti , H. Orland

Advanced structure prediction methods developed over the past decades include an unorthodox strategy of allowing atoms to displace into extra dimensions. A recently implemented global optimization of structures from hyperspace (GOSH) has…

Materials Science · Physics 2025-07-21 Daviti Gochitashvili , Maxwell Meyers , Cindy Wang , Aleksey N. Kolmogorov

Recent advances in deep learning have enabled the generation of realistic data by training generative models on large datasets of text, images, and audio. While these models have demonstrated exceptional performance in generating novel and…

Materials Science · Physics 2024-06-17 Izumi Takahara , Kiyou Shibata , Teruyasu Mizoguchi

The discovery of functional molecules is an expensive and time-consuming process, exemplified by the rising costs of small molecule therapeutic discovery. One class of techniques of growing interest for early-stage drug discovery is de novo…

Quantitative Methods · Quantitative Biology 2020-02-18 Wenhao Gao , Connor W. Coley

The recently developed evolutionary algorithm USPEX proved to be a tool that enables accurate and reliable prediction of structures for a given chemical composition. Here we extend this method to predict the crystal structure of polymers by…

Materials Science · Physics 2019-01-03 Qiang Zhu , Vinit Sharma , Artem R Oganov , Rampi Ramprasad

De novo crystal generation seeks to discover materials that are not merely realistic, but also stable and novel. However, most existing generative models are trained to maximize the likelihood of observed crystals, which encourages samples…

A key problem in computational material science deals with understanding the effect of material distribution (i.e., microstructure) on material performance. The challenge is to synthesize microstructures, given a finite number of…

Structural defects are ubiquitous in condensed matter, and not always a nuisance. For example, they underlie phenomena such as Anderson localization and hyperuniformity, and they are now being exploited to engineer novel materials. Here, we…

The rational design of molecules with desired properties is a long-standing challenge in chemistry. Generative neural networks have emerged as a powerful approach to sample novel molecules from a learned distribution. Here, we propose a…

Generative AI (GenAI) has demonstrated remarkable capabilities in code generation, and its integration into complex product modeling and simulation code generation can significantly enhance the efficiency of the system design phase in…

Software Engineering · Computer Science 2025-03-11 Lin Zhang , Yuteng Zhang , Dusit Niyato , Lei Ren , Pengfei Gu , Zhen Chen , Yuanjun Laili , Wentong Cai , Agostino Bruzzone

Machine learning potentials (MLPs) have become indispensable for conducting accurate large-scale atomistic simulations and for the efficient prediction of crystal structures. Polynomial MLPs, defined by polynomial rotational invariants,…

Materials Science · Physics 2024-08-05 Atsuto Seko
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