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By the ALARA (As Low As Reasonably Achievable) principle, ultra-low-dose CT reconstruction is a holy grail to minimize cancer risks and genetic damages, especially for children. With the development of medical CT technologies, the iterative…

Image and Video Processing · Electrical Eng. & Systems 2021-06-21 Weiwen Wu , Chuang Niu , Shadi Ebrahimian , Hengyong Yu , Mannu Kalra , Ge Wang

Low-dose CT (LDCT) imaging is widely used to reduce radiation exposure to mitigate high exposure side effects, but often suffers from noise and artifacts that affect diagnostic accuracy. To tackle this issue, deep learning models have been…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Taifour Yousra , Beghdadi Azeddine , Marie Luong , Zuheng Ming

X-ray photon-counting computed tomography (PCCT) for extremity allows multi-energy high-resolution (HR) imaging but its radiation dose can be further improved. Despite the great potential of deep learning techniques, their application in HR…

The field of medical image reconstruction has seen roughly four types of methods. The first type tended to be analytical methods, such as filtered back-projection (FBP) for X-ray computed tomography (CT) and the inverse Fourier transform…

Image and Video Processing · Electrical Eng. & Systems 2019-08-19 Saiprasad Ravishankar , Jong Chul Ye , Jeffrey A. Fessler

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

The unrolling method has been investigated for learning variational models in X-ray computed tomography. However, it has been observed that directly unrolling the regularization model through gradient descent does not produce satisfactory…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Yijie Yang , Qifeng Gao , Yuping Duan

X-ray imaging dose from serial cone-beam CT (CBCT) scans raises a clinical concern in most image guided radiation therapy procedures. It is the goal of this paper to develop a fast GPU-based algorithm to reconstruct high quality CBCT images…

Medical Physics · Physics 2015-05-19 Xun Jia , Bin Dong , Yifei Lou , Steve B. Jiang

Limited angle problem is a challenging issue in x-ray computed tomography (CT) field. Iterative reconstruction methods that utilize the additional prior can suppress artifacts and improve image quality, but unfortunately require increased…

Medical Physics · Physics 2016-10-04 Hanming Zhang , Liang Li , Kai Qiao , Linyuan Wang , Bin Yan , Lei Li , Guoen Hu

PURPOSE: We develop a practical, iterative algorithm for image-reconstruction in under-sampled tomographic systems, such as digital breast tomosynthesis (DBT). METHOD: The algorithm controls image regularity by minimizing the image total…

Denoising of clinical CT images is an active area for deep learning research. Current clinically approved methods use iterative reconstruction methods to reduce the noise in CT images. Iterative reconstruction techniques require multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Mayank Patwari , Ralf Gutjahr , Rainer Raupach , Andreas Maier

Recently, generative diffusion priors have made huge strides as inverse problem solvers, including the ability to be adapted for inference on out-of-distribution data. Concurrently, implicit neural representations (INRs) have emerged as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Maliha Hossain , Haley Duba-Sullivan , Amirkoushyar Ziabari

Deep learning (DL) reconstruction particularly of MRI has led to improvements in image fidelity and reduction of acquisition time. In neuroimaging, DL methods can reconstruct high-quality images from undersampled data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Yuning Du , Yuyang Xue , Rohan Dharmakumar , Sotirios A. Tsaftaris

Limited-view computed tomography (CT) presents significant potential for reducing radiation exposure and expediting the scanning process. While deep learning (DL) methods have exhibited promising results in mitigating streaking artifacts…

Medical Physics · Physics 2025-02-18 Changyu Chen , Li Zhang , Yuxiang Xing , Zhiqiang Chen

Deep learning (DL) has recently emerged to address the heavy storage and computation requirements of the baseline dictionary-matching (DM) for Magnetic Resonance Fingerprinting (MRF) reconstruction. Fed with non-iterated back-projected…

Computer Vision and Pattern Recognition · Computer Science 2019-02-28 Mohammad Golbabaee , Carolin M. Pirkl , Marion I. Menzel , Guido Buonincontri , Pedro A. Gómez

Model based iterative reconstruction (MBIR) algorithms for low-dose X-ray CT are computationally complex because of the repeated use of the forward and backward projection. Inspired by this success of deep learning in computer vision…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Eunhee Kang , junhong Min , Jong Chul Ye

Medical imaging is nowadays a pillar in diagnostics and therapeutic follow-up. Current research tries to integrate established - but ionizing - tomographic techniques with technologies offering reduced radiation exposure. Diffuse Optical…

Numerical Analysis · Mathematics 2024-02-15 Alessandro Benfenati , Paola Causin , Martina Quinteri

In this work, we propose a new paradigm of iterative model-based reconstruction algorithms for providing real-time solution for zooming-in and refining a region of interest in medical and clinical tomographic images. This algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 Junqi Tang , Guixian Xu , Jinglai Li

Deep learning has been successfully applied to low-dose CT (LDCT) image denoising for reducing potential radiation risk. However, the widely reported supervised LDCT denoising networks require a training set of paired images, which is…

Machine Learning · Computer Science 2023-02-09 Yuhui Ruan , Qiao Yuan , Chuang Niu , Chen Li , Yudong Yao , Ge Wang , Yueyang Teng

Repeated computed tomography (CT) scans are required in some clinical applications such as image-guided radiotherapy and follow-up observations over a time period. To optimize the radiation dose utility, a normal-dose (or full-dose) CT scan…

Medical Physics · Physics 2017-02-23 Hao Zhang , Jianhua Ma , William Moore , Zhengrong Liang

Diffusion models (DMs) have exhibited remarkable efficacy in various image restoration tasks. However, existing approaches typically operate within the high-dimensional pixel space, resulting in high computational overhead. While methods…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Yang Zheng , Wen Li , Zhaoqiang Liu
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