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This paper presents a novel DNA sequences alignment method based on inverted index. Now most large scale information retrieval system are all use inverted index as the basic data structure. But its application in DNA sequence alignment is…

Genomics · Quantitative Biology 2013-07-02 Wang Liang , Zhao KaiYong

Machine learning for data-driven diagnosis has been actively studied in medicine to provide better healthcare. Supporting analysis of a patient cohort similar to a patient under treatment is a key task for clinicians to make decisions with…

Medical Physics · Physics 2020-03-25 Rongchen Guo , Takanori Fujiwara , Yiran Li , Kelly M. Lima , Soman Sen , Nam K. Tran , Kwan-Liu Ma

The task of clustering unlabeled time series and sequences entails a particular set of challenges, namely to adequately model temporal relations and variable sequence lengths. If these challenges are not properly handled, the resulting…

Machine Learning · Statistics 2019-02-19 Daniel J. Trosten , Andreas S. Strauman , Michael Kampffmeyer , Robert Jenssen

The classification of amino acids and their sequence analysis plays a vital role in life sciences and is a challenging task. This article uses and compares state-of-the-art deep learning models like convolution neural networks (CNN), long…

Biomolecules · Quantitative Biology 2022-07-26 Sarwar Khan , Faisal Ghaffar , Imad Ali , Qazi Mazhar

Learning with few labeled data is a key challenge for visual recognition, as deep neural networks tend to overfit using a few samples only. One of the Few-shot learning methods called metric learning addresses this challenge by first…

Computer Vision and Pattern Recognition · Computer Science 2022-03-28 Li Ke , Meng Pan , Weigao Wen , Dong Li

Clustering high-dimensional datasets is hard because interpoint distances become less informative in high-dimensional spaces. We present a clustering algorithm that performs nonlinear dimensionality reduction and clustering jointly. The…

Machine Learning · Computer Science 2018-03-06 Sohil Atul Shah , Vladlen Koltun

The emerging field of DNA storage employs strands of DNA bases (A/T/C/G) as a storage medium for digital information to enable massive density and durability. The DNA storage pipeline includes: (1) encoding the raw data into sequences of…

Genomics · Quantitative Biology 2025-01-28 Hadas Abraham , Barak Gahtan , Adir Kobovich , Orian Leitersdorf , Alex M. Bronstein , Eitan Yaakobi

Sequence classification is the supervised learning task of building models that predict class labels of unseen sequences of symbols. Although accuracy is paramount, in certain scenarios interpretability is a must. Unfortunately, such…

Machine Learning · Computer Science 2020-06-26 Severin Gsponer , Luca Costabello , Chan Le Van , Sumit Pai , Christophe Gueret , Georgiana Ifrim , Freddy Lecue

The task of node classification is to infer unknown node labels, given the labels for some of the nodes along with the network structure and other node attributes. Typically, approaches for this task assume homophily, whereby neighboring…

Social and Information Networks · Computer Science 2021-09-15 Arpit Merchant , Michael Mathioudakis

Node embedding methods find latent lower-dimensional representations which are used as features in machine learning models. In the last few years, these methods have become extremely popular as a replacement for manual feature engineering.…

Social and Information Networks · Computer Science 2020-06-01 Christoph Martin , Meike Riebeling

Standard deep neural networks (DNNs) are commonly trained in an end-to-end fashion for specific tasks such as object recognition, face identification, or character recognition, among many examples. This specificity often leads to…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Raphaël Achddou , J. Matias di Martino , Guillermo Sapiro

Nearest neighbor search aims to obtain the samples in the database with the smallest distances from them to the queries, which is a basic task in a range of fields, including computer vision and data mining. Hashing is one of the most…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Xiao Luo , Haixin Wang , Daqing Wu , Chong Chen , Minghua Deng , Jianqiang Huang , Xian-Sheng Hua

Various methods have been developed to analyze the association between organisms and their genomic sequences. Among them, sequence alignment is the most frequently used for comparative analysis of biological genomes. However, the…

Quantitative Methods · Quantitative Biology 2020-10-27 Yong Joon Song , Dong Jin Ji , Hye In Seo , Gyu Bum Han , Dong Ho Cho

Unsupervised domain adaptation aiming to learn a specific task for one domain using another domain data has emerged to address the labeling issue in supervised learning, especially because it is difficult to obtain massive amounts of…

Machine Learning · Computer Science 2019-03-13 Jaeyoon Yoo , Changhwa Park , Yongjun Hong , Sungroh Yoon

Motivation: Spliced alignment refers to the alignment of messenger RNA (mRNA) or protein sequences to eukaryotic genomes. It plays a critical role in gene annotation and the study of gene functions. Accurate spliced alignment demands…

Genomics · Quantitative Biology 2025-09-23 Siying Yang , Neng Huang , Heng Li

It is argued that deep learning is efficient for data that is generated from hierarchal generative models. Examples of such generative models include wavelet scattering networks, functions of compositional structure, and deep rendering…

Machine Learning · Computer Science 2018-09-06 Elchanan Mossel

Biological sequence analysis relies on the ability to denoise the imprecise output of sequencing platforms. We consider a common setting where a short sequence is read out repeatedly using a high-throughput long-read platform to generate…

Genomics · Quantitative Biology 2023-09-06 Nathan Ng , Ji Won Park , Jae Hyeon Lee , Ryan Lewis Kelly , Stephen Ra , Kyunghyun Cho

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

Biological sequence comparison is a key step in inferring the relatedness of various organisms and the functional similarity of their components. Thanks to the Next Generation Sequencing efforts, an abundance of sequence data is now…

Machine Learning · Computer Science 2016-09-13 Dhananjay Kimothi , Akshay Soni , Pravesh Biyani , James M. Hogan

Network Embeddings (NEs) map the nodes of a given network into $d$-dimensional Euclidean space $\mathbb{R}^d$. Ideally, this mapping is such that `similar' nodes are mapped onto nearby points, such that the NE can be used for purposes such…

Machine Learning · Statistics 2018-10-17 Bo Kang , Jefrey Lijffijt , Tijl De Bie