Related papers: Unaligned Sequence Similarity Search Using Deep Le…
Deep neural networks (DNN) have shown remarkable success in the classification of physiological signals. In this study we propose a method for examining to what extent does a DNN's performance rely on rediscovering existing features of the…
The capability of accurate prediction of protein functions and properties is essential in the biotechnology industry, e.g. drug development and artificial protein synthesis, etc. The main challenges of protein function prediction are the…
Deep learning has produced state-of-the-art results for a variety of tasks. While such approaches for supervised learning have performed well, they assume that training and testing data are drawn from the same distribution, which may not…
The paper proposes to employ deep convolutional neural networks (CNNs) to classify noncoding RNA (ncRNA) sequences. To this end, we first propose an efficient approach to convert the RNA sequences into images characterizing their…
For challenging machine learning problems such as zero-shot learning and fine-grained categorization, embedding learning is the machinery of choice because of its ability to learn generic notions of similarity, as opposed to class-specific…
Complex nonlinear dynamics are ubiquitous in many fields. Moreover, we rarely have access to all of the relevant state variables governing the dynamics. Delay embedding allows us, in principle, to account for unobserved state variables.…
Deep neural networks (DNNs) achieve state-of-the-art results in a variety of domains. Unfortunately, DNNs are notorious for their non-interpretability, and thus limit their applicability in hypothesis-driven domains such as biology and…
Harvesting dense pixel-level annotations to train deep neural networks for semantic segmentation is extremely expensive and unwieldy at scale. While learning from synthetic data where labels are readily available sounds promising,…
Network alignment (NA) is the task of finding the correspondence of nodes between two networks based on the network structure and node attributes. Our study is motivated by the fact that, since most of existing NA methods have attempted to…
In this paper we describe a new technique for the comparison of populations of DNA strands. Comparison is vital to the study of ecological systems, at both the micro and macro scales. Existing methods make use of DNA sequencing and cloning,…
Most techniques for explainable machine learning focus on feature attribution, i.e., values are assigned to the features such that their sum equals the prediction. Example attribution is another form of explanation that assigns weights to…
The knowledge that humans hold about a problem often extends far beyond a set of training data and output labels. While the success of deep learning mostly relies on supervised training, important properties cannot be inferred efficiently…
This paper provides a new similarity detection algorithm. Given an input set of multi-dimensional data points, where each data point is assumed to be multi-dimensional, and an additional reference data point for similarity finding, the…
The statistical properties of local alignment algorithms with gaps are analyzed theoretically for uncorrelated and correlated DNA sequences. In the vicinity of the log-linear phase transition, the statistics of alignment with gaps is shown…
Hashing is at the heart of large-scale image similarity search, and recent methods have been substantially improved through deep learning techniques. Such algorithms typically learn continuous embeddings of the data. To avoid a subsequent…
Measuring similarity between IP addresses is an important task in the daily operations of any enterprise network. Applications that depend on an IP similarity measure include measuring correlation between security alerts, building baselines…
Classifying large-scale image data into object categories is an important problem that has received increasing research attention. Given the huge amount of data, non-parametric approaches such as nearest neighbor classifiers have shown…
BACKGROUND: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. This mode of protein function assignment is mostly…
Sequence comparison is a prerequisite to virtually all comparative genomic analyses. It is often realized by sequence alignment techniques, which are computationally expensive. This has led to increased research into alignment-free…
Metagenomic studies have increasingly utilized sequencing technologies in order to analyze DNA fragments found in environmental samples.One important step in this analysis is the taxonomic classification of the DNA fragments. Conventional…