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Accurate histopathological diagnosis often requires multiple differently stained tissue sections, a process that is time-consuming, labor-intensive, and environmentally taxing due to the use of multiple chemical stains. Recently, virtual…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Jiabo MA , Wenqiang Li , Jinbang Li , Ziyi Liu , Linshan Wu , Fengtao Zhou , Li Liang , Ronald Cheong Kin Chan , Terence T. W. Wong , Hao Chen

Accurate skin disease classification is a critical yet challenging task due to high inter-class similarity, intra-class variability, and complex lesion textures. While deep learning-based computer-aided diagnosis (CAD) systems have shown…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Enam Ahmed Taufik , Abdullah Khondoker , Antara Firoz Parsa , Seraj Al Mahmud Mostafa

Skin cancer is a widespread, global, and potentially deadly disease, which over the last three decades has afflicted more lives in the USA than all other forms of cancer combined. There have been a lot of promising recent works utilizing…

Computer Vision and Pattern Recognition · Computer Science 2018-05-15 Sara Ross-Howe , H. R. Tizhoosh

Computed medical imaging systems require a computational reconstruction procedure for image formation. In order to recover a useful estimate of the object to-be-imaged when the recorded measurements are incomplete, prior knowledge about the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-21 Varun A. Kelkar , Mark A. Anastasio

Anonymization and data sharing are crucial for privacy protection and acquisition of large datasets for medical image analysis. This is a big challenge, especially for neuroimaging. Here, the brain's unique structure allows for…

In the field of deep learning, large architectures often obtain the best performance for many tasks, but also require massive datasets. In the histological domain, tissue images are expensive to obtain and constitute sensitive medical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Andrei-Alexandru Preda , Iulian-Marius Tăiatu , Dumitru-Clementin Cercel

Multi-focus image fusion technologies compress different focus depth images into an image in which most objects are in focus. However, although existing image fusion techniques, including traditional algorithms and deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-06 Xiebo Geng , Sibo Liua , Wei Han , Xu Li , Jiabo Ma , Jingya Yu , Xiuli Liu , Sahoqun Zeng , Li Chen , Shenghua Cheng

Fluorescence microscopy is a widely used method among cell biologists for studying the localization and co-localization of fluorescent protein. For microbial cell biologists, these studies often include tedious and time-consuming manual…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Jonathan Reiner , Guy Azran , Gal Hyams

Multiplex immunofluorescence (mIF) enables simultaneous single-cell quantification of multiple biomarkers within intact tissue architecture, yet its high reagent cost, multi-round staining protocols, and need for specialized imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Junhyeok Lee , Han Jang , Heeseong Eum , Joon Jang , Kyu Sung Choi

Conditional generative adversarial networks (cGANs) have enabled high-fidelity computational staining and destaining of hematoxylin and eosin (H&E) in digital pathology whole-slide images (WSI). However, their ability to generalize to…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Aarushi Kulkarni , Alarice Lowe , Pratik Shah

Fine-grained image search is still a challenging problem due to the difficulty in capturing subtle differences regardless of pose variations of objects from fine-grained categories. In practice, a dynamic inventory with new fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2018-07-09 Kevin Lin , Fan Yang , Qiaosong Wang , Robinson Piramuthu

Histopathology relies on the analysis of microscopic tissue images to diagnose disease. A crucial part of tissue preparation is staining whereby a dye is used to make the salient tissue components more distinguishable. However, differences…

Image and Video Processing · Electrical Eng. & Systems 2022-08-03 Haseeb Nazki , Ognjen Arandjelović , InHwa Um , David Harrison

The utilisation of deep learning segmentation algorithms that learn complex organs and tissue patterns and extract essential regions of interest from the noisy background to improve the visual ability for medical image diagnosis has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-03 Yanming Guo

Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Hana Sebia , Thomas Guyet , Mickaël Pereira , Marco Valdebenito , Hugues Berry , Benjamin Vidal

Automatic detection and tracking of cells in microscopy images are major applications of computer vision technologies in both biomedical research and clinical practice. Though machine learning methods are increasingly common in these…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Nikomidisz Eftimiu , Michal Kozubek

The classification of forged videos has been a challenge for the past few years. Deepfake classifiers can now reliably predict whether or not video frames have been tampered with. However, their performance is tied to both the dataset used…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Matthieu Delmas , Renaud Seguier

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

We leverage deep learning techniques to jointly denoise and super-resolve biomedical images acquired with fluorescence microscopy. We develop a deep learning algorithm based on the networks and method described in the recent W2S paper to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-24 Martin Chatton

In recent years, an enormous amount of fluorescence microscopy images were collected in high-throughput lab settings. Analyzing and extracting relevant information from all images in a short time is almost impossible. Detecting tiny…

Computer Vision and Pattern Recognition · Computer Science 2021-04-08 Asmaa Haja , Lambert R. B. Schomaker

Simulating in silico cellular responses to interventions is a promising direction to accelerate high-content image-based assays, critical for advancing drug discovery and gene editing. To support this, we introduce MorphGen, a…

Quantitative Methods · Quantitative Biology 2025-10-13 Berker Demirel , Marco Fumero , Theofanis Karaletsos , Francesco Locatello