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With the rapid development of diffusion models and flow-based generative models, there has been a surge of interests in solving noisy linear inverse problems, e.g., super-resolution, deblurring, denoising, colorization, etc, with generative…

Machine Learning · Computer Science 2024-10-22 Xiangming Meng , Yoshiyuki Kabashima

In this work, an inverse problem on the determination of multiple coefficients arising from the time-domain diffuse optical tomography with fluorescence (DOT-FDOT) is investigated. We simultaneously recover the distribution of background…

Numerical Analysis · Mathematics 2023-11-23 Zhiyuan Li , Chunlong Sun

Two-dimensional (2D) fluorescence-excitation (2D-FLEX) spectroscopy is a recently proposed nonlinear femtosecond technique for the detection of photoinduced dynamics. The method records a time-resolved fluorescence signal in its excitation-…

Chemical Physics · Physics 2024-06-24 Sebastian V. Pios , Maxim F. Gelin , Luis Vasquez , Jürgen Hauer , Lipeng Chen

Single-molecule localization microscopy (SMLM) allows reconstructing biology-relevant structures beyond the diffraction limit by detecting and localizing individual fluorophores -- fluorescent molecules stained onto the observed specimen --…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Romain Seailles , Jean-Baptiste Masson , Jean Ponce , Julien Mairal

In this paper, the problem of compressive imaging is addressed using natural randomization by means of a multiply scattering medium. To utilize the medium in this way, its corresponding transmission matrix must be estimated. To calibrate…

Computer Vision and Pattern Recognition · Computer Science 2016-08-26 Boshra Rajaei , Eric W. Tramel , Sylvain Gigan , Florent Krzakala , Laurent Daudet

We consider a general setting for dynamic tensor field tomography in an inhomogeneous refracting and absorbing medium as inverse source problem for the associated transport equation. Following Fermat's principle the Riemannian metric in the…

Analysis of PDEs · Mathematics 2021-11-11 Lukas Vierus , Thomas Schuster

Super-resolution microscopy is rapidly gaining importance as an analytical tool in the life sciences. A compelling feature is the ability to label biological units of interest with fluorescent markers in living cells and to observe them…

Diffusion models have achieved remarkable success in imaging inverse problems owing to their powerful generative capabilities. However, existing approaches typically rely on models trained for specific degradation types, limiting their…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Zhen Wang , Hongyi Liu , Zhihui Wei

We propose a new compressive imaging method for reconstructing 2D or 3D objects from their scattered wave-field measurements. Our method relies on a novel, nonlinear measurement model that can account for the multiple scattering phenomenon,…

Computer Vision and Pattern Recognition · Computer Science 2016-10-07 Hsiou-Yuan Liu , Ulugbek S. Kamilov , Dehong Liu , Hassan Mansour , Petros T. Boufounos

Ultrasound modulated bioluminescence tomography (UMBLT) is an imaging method which can be formulated as a hybrid inverse source problem. In the regime where light propagation is modeled by a radiative transfer equation, previous approaches…

Analysis of PDEs · Mathematics 2020-08-14 Francis Chung , Tianyu Yang , Yang Yang

In this paper, we propose a novel projector-camera system for practical and low-cost acquisition of a dense object 3D model with the spectral reflectance property. In our system, we use a standard RGB camera and leverage an off-the-shelf…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Chunyu Li , Yusuke Monno , Hironori Hidaka , Masatoshi Okutomi

Phase retrieval is a nonlinear inverse problem that arises in a wide range of imaging modalities, from electron microscopy to Fourier ptychography. In particular, the reconstruction is facilitated when the sensing matrix is i.i.d. random,…

Deblurring is a fundamental inverse problem in bioimaging. It requires modelling the point spread function (PSF), which captures the optical distortions entailed by the image formation process. The PSF limits the spatial resolution…

Image and Video Processing · Electrical Eng. & Systems 2019-03-04 Denis K. Samuylov , Prateek Purwar , Gábor Székely , Grégory Paul

In this paper, motivated by diffraction of traveling light waves, a simple mathematical model is proposed, both for the multivariate super-resolution problem and the problem of blind-source separation of real-valued exponential sums. This…

Numerical Analysis · Mathematics 2017-08-01 Charles K. Chui , Hrushikesh N. Mhaskar

A unified method for three-dimensional reconstruction of objects from transmission images collected at multiple illumination directions is described. The method may be applicable to experimental conditions relevant to absorption-based,…

Medical Physics · Physics 2022-12-07 Timur E. Gureyev , Hamish G. Brown , Harry M. Quiney , Leslie J. Allen

The paper studies an imaging problem in the diffusive ultrasound-modulated bioluminescence tomography with partial boundary measurement in an anisotropic medium. Assuming plane-wave modulation, we transform the imaging problem to an inverse…

Analysis of PDEs · Mathematics 2024-04-05 Tianyu Yang , Yang Yang

Molecule-surface interaction is key to many physical and chemical processes at interfaces. Here, we show that the dynamics of single molecules on a surface under ultrahigh vacuum can be resolved using fluorescence imaging. By adapting…

Chemical Physics · Physics 2021-10-19 Tianyu Fang , Florian Elsen , Nick Vogeley , Daqing Wang

Imaging inverse problems can be solved in an unsupervised manner using pre-trained diffusion models, but doing so requires approximating the gradient of the measurement-conditional score function in the diffusion reverse process. We show…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Matt C. Bendel , Saurav K. Shastri , Rizwan Ahmad , Philip Schniter

Light-sheet fluorescence microscopy (LSFM) is used to capture volume images of biological specimens. It offers high contrast deep inside densely fluorescence labelled samples, fast acquisition speed and minimal harmful effects on the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-05 Niklas Rottmayer , Claudia Redenbach , Florian Fahrbach

We show that structural information can be extracted from single molecule localization microscopy (SMLM) data. More precisely, we reinterpret SMLM data as the measures of a phaseless optical diffraction tomography system for which the…

Signal Processing · Electrical Eng. & Systems 2023-07-19 Thanh-An Pham , Emmanuel Soubies , Ferréol Soulez , Michael Unser