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Natural language processing techniques are being applied to increasingly diverse types of electronic health records, and can benefit from in-depth understanding of the distinguishing characteristics of medical document types. We present a…

Computation and Language · Computer Science 2019-10-02 Denis Newman-Griffis , Eric Fosler-Lussier

In this study, we investigate the potential of Large Language Models to complement biomedical knowledge graphs in the training of semantic models for the biomedical and clinical domains. Drawing on the wealth of the UMLS knowledge graph and…

Computation and Language · Computer Science 2023-11-28 François Remy , Kris Demuynck , Thomas Demeester

Natural language inference (NLI) is critical for complex decision-making in biomedical domain. One key question, for example, is whether a given biomedical mechanism is supported by experimental evidence. This can be seen as an NLI problem…

Computation and Language · Computer Science 2022-10-27 Mohaddeseh Bastan , Mihai Surdeanu , Niranjan Balasubramanian

Here we present a holistic approach for data exploration on dense knowledge graphs as a novel approach with a proof-of-concept in biomedical research. Knowledge graphs are increasingly becoming a vital factor in knowledge mining and…

Artificial Intelligence · Computer Science 2019-12-16 Jens Dörpinghaus , Alexander Apke , Vanessa Lage-Rupprecht , Andreas Stefan

The recent proliferation of publicly available graph-structured data has sparked an interest in machine learning algorithms for graph data. Since most traditional machine learning algorithms assume data to be tabular, embedding algorithms…

Machine Learning · Computer Science 2019-08-09 Sourav Mukherjee , Tim Oates , Ryan Wright

Drug repurposing is more relevant than ever due to drug development's rising costs and the need to respond to emerging diseases quickly. Knowledge graph embedding enables drug repurposing using heterogeneous data sources combined with…

Knowledge infusion is a promising method for enhancing Large Language Models for domain-specific NLP tasks rather than pre-training models over large data from scratch. These augmented LLMs typically depend on additional pre-training or…

Computation and Language · Computer Science 2024-03-05 Kinshuk Vasisht , Balaji Ganesan , Vikas Kumar , Vasudha Bhatnagar

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

The increasing depth of parametric domain knowledge in large language models (LLMs) is fueling their rapid deployment in real-world applications. Understanding model vulnerabilities in high-stakes and knowledge-intensive tasks is essential…

Computation and Language · Computer Science 2024-12-02 R. Patrick Xian , Alex J. Lee , Satvik Lolla , Vincent Wang , Qiming Cui , Russell Ro , Reza Abbasi-Asl

In this work, we consider the medical concept normalization problem, i.e., the problem of mapping a health-related entity mention in a free-form text to a concept in a controlled vocabulary, usually to the standard thesaurus in the Unified…

Computation and Language · Computer Science 2023-11-21 Zulfat Miftahutdinov , Elena Tutubalina

The clinical named entity recognition (CNER) task seeks to locate and classify clinical terminologies into predefined categories, such as diagnostic procedure, disease disorder, severity, medication, medication dosage, and sign symptom.…

Computation and Language · Computer Science 2021-06-25 Yichao Zhou , Chelsea Ju , J. Harry Caufield , Kevin Shih , Calvin Chen , Yizhou Sun , Kai-Wei Chang , Peipei Ping , Wei Wang

In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic…

Artificial Intelligence · Computer Science 2025-09-01 Saman Marandi , Yu-Shu Hu , Mohammad Modarres

Knowledge graphs are freely aggregated, published, and edited in the Web of data, and thus may overlap. Hence, a key task resides in aligning (or matching) their content. This task encompasses the identification, within an aggregated…

Machine Learning · Computer Science 2021-10-22 Pierre Monnin , Chedy Raïssi , Amedeo Napoli , Adrien Coulet

The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

Computation and Language · Computer Science 2023-07-04 Qinyong Wang , Zhenxiang Gao , Rong Xu

The automatic construction of knowledge graphs (KGs) is an important research area in medicine, with far-reaching applications spanning drug discovery and clinical trial design. These applications hinge on the accurate identification of…

Computation and Language · Computer Science 2025-01-30 Vahan Arsenyan , Spartak Bughdaryan , Fadi Shaya , Kent Small , Davit Shahnazaryan

Deep learning (DL) based language models achieve high performance on various benchmarks for Natural Language Inference (NLI). And at this time, symbolic approaches to NLI are receiving less attention. Both approaches (symbolic and DL) have…

Computation and Language · Computer Science 2021-06-11 Zeming Chen , Qiyue Gao , Lawrence S. Moss

This paper proposes a large language model (LLM) approach that integrates graph-structured information for knowledge reasoning in tobacco pest and disease control. Built upon the GraphRAG framework, the proposed method enhances knowledge…

Computation and Language · Computer Science 2025-12-29 Siyu Li , Chenwei Song , Wan Zhou , Xinyi Liu

Disease name recognition and normalization, which is generally called biomedical entity linking, is a fundamental process in biomedical text mining. Recently, neural joint learning of both tasks has been proposed to utilize the mutual…

Computation and Language · Computer Science 2021-04-22 Shogo Ujiie , Hayate Iso , Shuntaro Yada , Shoko Wakamiya , Eiji Aramaki

Neuroscience research publications encompass a vast wealth of knowledge. Accurately retrieving existing information and discovering new insights from this extensive literature is essential for advancing the field. However, when knowledge is…

Computation and Language · Computer Science 2025-10-28 Pralaypati Ta , Sriram Venkatesaperumal , Keerthi Ram , Mohanasankar Sivaprakasam

The integration of multi-omic data is pivotal for understanding complex diseases, but its high dimensionality and noise present significant challenges. Graph Neural Networks (GNNs) offer a robust framework for analyzing large-scale…

Quantitative Methods · Quantitative Biology 2024-12-23 Heming Zhang , Di Huang , Yixin Chen , Fuhai Li