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Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Knowledge graphs, on top of entities and their relationships, contain other important elements: literals. Literals encode interesting properties (e.g. the height) of entities that are not captured by links between entities alone. Most of…

Artificial Intelligence · Computer Science 2019-07-19 Agustinus Kristiadi , Mohammad Asif Khan , Denis Lukovnikov , Jens Lehmann , Asja Fischer

Gene expression datasets offer insights into gene regulation mechanisms, biochemical pathways, and cellular functions. Additionally, comparing gene expression profiles between disease and control patients can deepen the understanding of…

Machine Learning · Computer Science 2025-03-27 Rita T. Sousa , Heiko Paulheim

Ultrasound robots are increasingly used in medical diagnostics and early disease screening. However, current ultrasound robots lack the intelligence to understand human intentions and instructions, hindering autonomous ultrasound scanning.…

Robotics · Computer Science 2024-06-20 Huan Xu , Jinlin Wu , Guanglin Cao , Zhen Lei , Zhen Chen , Hongbin Liu

Electronic medical records contain multi-format electronic medical data that consist of an abundance of medical knowledge. Facing with patient's symptoms, experienced caregivers make right medical decisions based on their professional…

Databases · Computer Science 2017-07-25 Meng Wang , Jiaheng Zhang , Jun Liu , Wei Hu , Sen Wang , Xue Li , Wenqiang Liu

Functioning is gaining recognition as an important indicator of global health, but remains under-studied in medical natural language processing research. We present the first analysis of automatically extracting descriptions of patient…

Computation and Language · Computer Science 2018-06-08 Denis Newman-Griffis , Ayah Zirikly

Word embeddings have been widely used in biomedical Natural Language Processing (NLP) applications as they provide vector representations of words capturing the semantic properties of words and the linguistic relationship between words.…

Information Retrieval · Computer Science 2018-07-20 Yanshan Wang , Sijia Liu , Naveed Afzal , Majid Rastegar-Mojarad , Liwei Wang , Feichen Shen , Paul Kingsbury , Hongfang Liu

Clinical text is rich in information, with mentions of treatment, medication and anatomy among many other clinical terms. Multiple terms can refer to the same core concepts which can be referred as a clinical entity. Ontologies like the…

Computation and Language · Computer Science 2024-05-28 Akshit Achara , Sanand Sasidharan , Gagan N

Recent studies on knowledge graph embedding focus on mapping entities and relations into low-dimensional vector spaces. While most existing models primarily exploit structural information, knowledge graphs also contain rich contextual and…

Computation and Language · Computer Science 2025-09-03 Qisong Li , Ji Lin , Sijia Wei , Neng Liu

Biomedical word embeddings are usually pre-trained on free text corpora with neural methods that capture local and global distributional properties. They are leveraged in downstream tasks using various neural architectures that are designed…

Computation and Language · Computer Science 2021-07-26 Jiho Noh , Ramakanth Kavuluru

The large-scale development of large language models (LLMs) in medical contexts, such as diagnostic assistance and treatment recommendations, necessitates that these models possess accurate medical knowledge and deliver traceable…

Artificial Intelligence · Computer Science 2025-08-12 Qiyuan Li , Haijiang Liu , Caicai Guo , Chao Gao , Deyu Chen , Meng Wang , Feng Gao , Frank van Harmelen , Jinguang Gu

Motivation: Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. In the past years, feature learning methods that are…

Quantitative Methods · Quantitative Biology 2017-05-01 Mona Alshahrani , Mohammed Asif Khan , Omar Maddouri , Akira R Kinjo , Núria Queralt-Rosinach , Robert Hoehndorf

Learning the underlying patterns in data goes beyond instance-based generalization to external knowledge represented in structured graphs or networks. Deep learning that primarily constitutes neural computing stream in AI has shown…

Artificial Intelligence · Computer Science 2023-09-04 Ugur Kursuncu , Manas Gaur , Amit Sheth

Graph Neural Networks (GNNs) have been widely used in diverse brain network analysis tasks based on preprocessed functional magnetic resonance imaging (fMRI) data. However, their performances are constrained due to high feature sparsity and…

Machine Learning · Computer Science 2026-04-13 Rui Dong , Zitong Wang , Jiaxing Li , Weihuang Zheng , Youyong Kong

In recent years, Deep Learning (DL) models are becoming important due to their demonstrated success at overcoming complex learning problems. DL models have been applied effectively for different Natural Language Processing (NLP) tasks such…

Computation and Language · Computer Science 2019-11-06 Hamada A. Nayel , Shashrekha H. L

Proteins perform much of the work in living organisms, and consequently the development of efficient computational methods for protein representation is essential for advancing large-scale biological research. Most current approaches…

Quantitative Methods · Quantitative Biology 2023-06-09 Francesco Ceccarelli , Lorenzo Giusti , Sean B. Holden , Pietro Liò

Large semantic knowledge bases are grounded in factual knowledge. However, recent approaches to dense text representations (i.e. embeddings) do not efficiently exploit these resources. Dense and robust representations of documents are…

Artificial Intelligence · Computer Science 2024-10-01 Boshko Koloski , Senja Pollak , Roberto Navigli , Blaž Škrlj

In this paper, we investigate a new approach to Population, Intervention and Outcome (PIO) element detection, a common task in Evidence Based Medicine (EBM). The purpose of this study is two-fold: to build a training dataset for PIO element…

Computation and Language · Computer Science 2019-06-27 Hichem Mezaoui , Aleksandr Gontcharov , Isuru Gunasekara

While Language Models (LMs) are the workhorses of NLP, their interplay with structured knowledge graphs (KGs) is still actively researched. Current methods for encoding such graphs typically either (i) linearize them for embedding with LMs…

Computation and Language · Computer Science 2024-06-04 Moritz Plenz , Anette Frank

A fundamental advantage of neural models for NLP is their ability to learn representations from scratch. However, in practice this often means ignoring existing external linguistic resources, e.g., WordNet or domain specific ontologies such…

Computation and Language · Computer Science 2017-04-26 Ye Zhang , Matthew Lease , Byron C. Wallace
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