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The short-time dynamics of bacterial chromosomal loci is a mixture of subdiffusive and active motion, in the form of rapid relocations with near-ballistic dynamics. While previous work has shown that such rapid motions are ubiquitous, we…

Soft Condensed Matter · Physics 2017-10-11 Marco Gherardi , Ludovico Calabrese , Mikhail Tamm , Marco Cosentino Lagomarsino

Culturing cells confined in microscale geometries has been reported in many studies this last decade, in particular following the development of microfluidic-based applications and lab-on-a-chip devices. Such studies usually examine growth…

We present a new reaction-diffusion model for chiral branching growth of colonies of the bacteria Paenibacillus dendritiformis. In our model the bacteria are represented by a density field with non-linear diffusion and a complex scalar…

Condensed Matter · Physics 2007-05-23 Inon Cohen , Eshel Ben-Jacob

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michele Bezzi , Andrea Ciliberto

Hybrid modeling provides an effective solution to cope with multiple time scales dynamics in systems biology. Among the applications of this method, one of the most important is the cell cycle regulation. The machinery of the cell cycle,…

Computational Engineering, Finance, and Science · Computer Science 2013-09-05 Vincent Noël , Sergey Vakulenko , Ovidiu Radulescu

Lymphocyte populations, stimulated in vitro or in vivo, grow as cells divide. Stochastic models are appropriate because some cells undergo multiple rounds of division, some die, and others of the same type in the same conditions do not…

Cell Behavior · Quantitative Biology 2021-12-02 Giulia Belluccini , Martín López-García , Grant Lythe , Carmen Molina-París

Hybrid models of chemotaxis combine agent-based models of cells with partial differential equation models of extracellular chemical signals. In this paper, travelling wave properties of hybrid models of bacterial chemotaxis are…

Biological Physics · Physics 2013-02-13 Benjamin Franz , Chuan Xue , Kevin J. Painter , Radek Erban

Living cells maintain size homeostasis by actively compensating for size fluctuations. Here, we present two stochastic maps that unify phenomenological models by integrating fluctuating single-cell growth rates and size-dependent noise…

Populations and Evolution · Quantitative Biology 2026-01-09 Arthur Genthon , Philipp Thomas

Uncovering the quantitative laws that govern the growth and division of single cells remains a major challenge. Using a unique combination of technologies that yields unprecedented statistical precision, we find that the sizes of individual…

Bacteria living on surfaces use different types of motility mechanisms to move on the surface in search of food or to form micro-colonies. Twitching is one such form of motility employed by bacteria such as N. gonorrhoeae, in which the…

Biological Physics · Physics 2020-04-29 Konark Bisht , Rahul Marathe

Microbial growth and division are fundamental processes relevant to many areas of life science. Of particular interest are homeostasis mechanisms, which buffer growth and division from accumulating fluctuations over multiple cycles. These…

Cell Behavior · Quantitative Biology 2022-10-12 Lee Susman , Maryam Kohram , Harsh Vashistha , Jeffrey T. Nechleba , Hanna Salman , Naama Brenner

We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description -molecular,…

Molecular Networks · Quantitative Biology 2007-05-23 J. M. G. Vilar , C. C. Guet , S. Leibler

While analyzing mobile systems we often approximate the actual coverage surface and assume an ideal cell shape. In a multi-cellular network, because of its tessellating nature, a hexagon is more preferred than a circular geometry. Despite…

Information Theory · Computer Science 2013-06-04 Mouhamed Abdulla , Yousef R. Shayan

Intracellular protein patterns govern essential cellular functions by dynamically redistributing proteins between membrane-bound and cytosolic states, conserving their total numbers. This review presents a theoretical framework for…

Biological Physics · Physics 2025-12-16 Erwin Frey , Henrik Weyer

In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via…

Condensed Matter · Physics 2007-05-23 Eshel Ben-Jacob , Inon Cohen , Ido Golding , Yonathan Kozlovsky

Understanding how growth induces form is a longstanding biological question. Many studies concentrated on the shapes of plant cells, fungi or bacteria. Some others have shown the importance of the mechanical properties of bacterial walls…

Biological Physics · Physics 2007-05-23 Arezki Boudaoud

The rotary motor of bacteria is a natural nano-technological marvel that enables cell locomotion by powering the rotation of semi-rigid helical flagellar filaments in fluid environments. It is well known that the motor operates essentially…

Biological Physics · Physics 2018-10-23 Debasish Das , Eric Lauga

The mechanics of crawling cells on a substrate is investigated by using a minimal model that satisfies the force-free condition. A cell is described by two subcellular elements connected by a linear actuator that changes the length of the…

Soft Condensed Matter · Physics 2018-04-18 Mitsusuke Tarama , Ryoichi Yamamoto

The building of minimal self-reproducing systems with a physical embodiment (generically called protocells) is a great challenge, with implications for both theory and applied sciences. Although the classical view of a living protocell…

Cell Behavior · Quantitative Biology 2009-09-29 Harold Fellermann , Ricard V. Solé

In this article a kinetic model for the dynamics of myxobacteria colonies on flat surfaces is investigated. The model is based on the kinetic equation for collective bacteria dynamics introduced in arXiv:2001.02711, which is based on the…

Analysis of PDEs · Mathematics 2021-09-28 Laura Kanzler , Christian Schmeiser