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Embedding projections are popular for visualizing large datasets and models. However, people often encounter "friction" when using embedding visualization tools: (1) barriers to adoption, e.g., tedious data wrangling and loading,…

Human-Computer Interaction · Computer Science 2025-07-09 Donghao Ren , Fred Hohman , Halden Lin , Dominik Moritz

Large language models (LLMs) and vision-language models (VLMs) have the potential to transform biological research by enabling autonomous experimentation. Yet, their application remains constrained by rigid protocol design, limited…

Robotics · Computer Science 2025-07-03 Yibo Qiu , Zan Huang , Zhiyu Wang , Handi Liu , Yiling Qiao , Yifeng Hu , Shu'ang Sun , Hangke Peng , Ronald X Xu , Mingzhai Sun

Multiple instance learning (MIL) is a promising approach for weakly supervised classification in pathology using whole slide images (WSIs). However, conventional MIL methods such as Attention-Based Deep Multiple Instance Learning (ABMIL)…

Image and Video Processing · Electrical Eng. & Systems 2025-04-28 Hassan Keshvarikhojasteh , Mihail Tifrea , Sibylle Hess , Josien P. W. Pluim , Mitko Veta

There are many ways to represent a molecule as input to a machine learning model and each is associated with loss and retention of certain kinds of information. In the interest of preserving three-dimensional spatial information, including…

Machine Learning · Computer Science 2019-12-11 Jocelyn Sunseri , David Ryan Koes

The Collective Variables Dashboard is a software tool for real-time, seamless exploration of molecular structures and trajectories in a customizable space of collective variables. The Dashboard arises from the integration of the Collective…

Computational Physics · Physics 2022-02-21 Jérôme Hénin , Laura J. S. Lopes , Giacomo Fiorin

Computational experiments using spatial stochastic simulations have led to important new biological insights, but they require specialized tools, a complex software stack, as well as large and scalable compute and data analysis resources…

Computational Engineering, Finance, and Science · Computer Science 2015-08-17 Brian Drawert , Michael Trogdon , Salman Toor , Linda Petzold , Andreas Hellander

The molecular simulations solve the equation of motion of molecular systems, making 3D shapes of molecules four-dimensional by adding the time coordinate. These methods have a great potential in drug discovery because they can realistically…

Biomolecules · Quantitative Biology 2023-01-19 Dalibor Trapl , Vojtěch Spiwok

Classical topological concepts are applied to understand high performance computing simulations of molecules writhing in three dimensional space. These simulations produce peta-bytes of floating point data, to describe 3 dimensional changes…

Geometric Topology · Mathematics 2013-04-23 J. Li , T. J. Peters , K. E. Jordan

Visual embedding models excel at zero-shot tasks like visual retrieval and classification. However, these models cannot be used for tasks that contain ambiguity or require user instruction. These tasks necessitate an embedding model which…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Benjamin Schneider , Florian Kerschbaum , Wenhu Chen

Quantum computing has the potential to reduce the computational cost required for quantum dynamics simulations. However, existing quantum algorithms for coupled electron-nuclear dynamics simulation either require fault-tolerant devices, or…

Quantum Physics · Physics 2026-03-03 Jong-Kwon Ha , Ryan J. MacDonell

This paper presents a software platform, named BiNS2, able to simulate diffusion-based molecular communications with drift inside blood vessels. The contribution of the paper is twofold. First a detailed description of the simulator is…

Computational Engineering, Finance, and Science · Computer Science 2013-08-16 Luca Felicetti , Mauro Femminella , Gianluca Reali

GROMACS is a widely used package for biomolecular simulation, and over the last two decades it has evolved from small-scale efficiency to advanced heterogeneous acceleration and multi-level parallelism targeting some of the largest…

Computational Engineering, Finance, and Science · Computer Science 2015-06-03 Páll Szilárd , Mark James Abraham , Carsten Kutzner , Berk Hess , Erik Lindahl

Quantum effects due to the spatial delocalization of light atoms are treated in molecular simulation via the path integral technique. Among several methods, Path Integral (PI) Molecular Dynamics (MD) is nowadays a powerful tool to…

Chemical Physics · Physics 2015-09-30 Animesh Agarwal , Luigi Delle Site

MiMiC is a framework for performing multiscale simulations in which loosely coupled external programs describe individual subsystems at different resolutions and levels of theory. To make it highly efficient and flexible, we adopt an…

PyMembrane is a software package for simulating liquid and elastic membranes using a discretisation of the continuum description based on unstructured triangulated two-dimensional meshes embedded in three-dimensional space. The package is…

Soft Condensed Matter · Physics 2023-08-25 D. A. Matoz-Fernandez , Siyu Li , Monica Olvera de la Cruz , Rastko Sknepnek

We present a web-based software tool, the Virtual Quantum Optics Laboratory (VQOL), that may be used for designing and executing realistic simulations of quantum optics experiments. A graphical user interface allows one to rapidly build and…

Quantum Physics · Physics 2022-10-20 Brian R. La Cour , Maria Maynard , Parth Shroff , Gabriel Ko , Evan Ellis

Dimensionality reduction methods have found vast application as visualization tools in diverse areas of science. Although many different methods exist, their performance is often insufficient for providing quick insight into many…

Explicit simulations of fluid mixtures of highly size-dispersed particles are constrained by numerical challenges associated with identifying pair-interaction neighbors. Recent algorithmic developments have ameliorated these difficulties to…

Soft Condensed Matter · Physics 2022-12-07 Joseph M. Monti , Gary S. Grest

This work introduces a novel Augmented Reality (AR) approach to visualize material data alongside real objects in order to facilitate detailed material analyses based on spatial non-destructive testing (NDT) data as generated in X-ray…

Human-Computer Interaction · Computer Science 2024-04-22 Alexander Gall , Anja Heim , Patrick Weinberger , Bernhard Fröhler , Johann Kastner , Christoph Heinzl

Acupuncture is a widely adopted medical practice that involves inserting thin needles into specific points on the body to alleviate pain and treat various health conditions. Current learning practices heavily rely on 2D atlases and practice…

Human-Computer Interaction · Computer Science 2024-07-04 Menghe Zhang , Chen Chen , Matin Yarmand , Anish Rajeshkumar , Nadir Weibel