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Information from neuroimaging examinations is increasingly used to support diagnoses of dementia, e.g., Alzheimer's disease. While current clinical practice is mainly based on visual inspection and feature engineering, Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Lisa Anita De Santi , Jörg Schlötterer , Michael Scheschenja , Joel Wessendorf , Meike Nauta , Vincenzo Positano , Christin Seifert

Application and use of deep learning algorithms for different healthcare applications is gaining interest at a steady pace. However, use of such algorithms can prove to be challenging as they require large amounts of training data that…

Machine Learning · Computer Science 2020-05-08 Anirudh Som , Narayanan Krishnamurthi , Matthew Buman , Pavan Turaga

Deep learning (DL) models have received particular attention in medical imaging due to their promising pattern recognition capabilities. However, Deep Neural Networks (DNNs) require a huge amount of data, and because of the lack of…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Donya Khaledyan , AmirReza Tajally , Ali Sarkhosh , Afshar Shamsi , Hamzeh Asgharnezhad , Abbas Khosravi , Saeid Nahavandi

Parkinson's disease (PD) is a progressive neurological disorder that impairs movement control, leading to symptoms such as tremors, stiffness, and bradykinesia. Many researchers analyzing handwriting data for PD detection typically rely on…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Jungpil Shin , Abu Saleh Musa Miah , Koki Hirooka , Md. Al Mehedi Hasan , Md. Maniruzzaman

Accurate assessment of Parkinsonian tremor is vital for monitoring disease progression and evaluating treatment efficacy. We introduce a pixel-based deep learning model designed to analyse postural tremor in Parkinson's disease (PD) from…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Felipe Duque-Quiceno , Grzegorz Sarapata , Yuriy Dushin , Miles Allen , Jonathan O'Keeffe

Parkinson's Disease (PD) affects over 10 million people globally, with speech impairments often preceding motor symptoms by years, making speech a valuable modality for early, non-invasive detection. While recent deep-learning models…

Sound · Computer Science 2025-08-29 Terry Yi Zhong , Cristian Tejedor-Garcia , Martha Larson , Bastiaan R. Bloem

Background. Clinical parameters measured from gated single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) have value in predicting cardiac resynchronization therapy (CRT) patient outcomes, but still show…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Kristoffer Larsena , Zhuo He , Chen Zhao , Xinwei Zhang , Quiying Sha , Claudio T Mesquitad , Diana Paeze , Ernest V. Garciaf , Jiangang Zou , Amalia Peix , Weihua Zhou

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

Disease progression models are instrumental in predicting individual-level health trajectories and understanding disease dynamics. Existing models are capable of providing either accurate predictions of patients prognoses or clinically…

Machine Learning · Computer Science 2018-10-25 Ahmed M. Alaa , Mihaela van der Schaar

Computed Tomography (CT) is commonly used to image acute ischemic stroke (AIS) patients, but its interpretation by radiologists is time-consuming and subject to inter-observer variability. Deep learning (DL) techniques can provide automated…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Alessandro Fontanella , Wenwen Li , Grant Mair , Antreas Antoniou , Eleanor Platt , Paul Armitage , Emanuele Trucco , Joanna Wardlaw , Amos Storkey

Changes in speech and language are among the first signs of Parkinson's disease (PD). Thus, clinicians have tried to identify individuals with PD from their voices for years. Doctors can leverage AI-based speech assessments to spot PD…

Sound · Computer Science 2023-12-06 Mahboobeh Parsapoor

As AI-based medical devices are becoming more common in imaging fields like radiology and histology, interpretability of the underlying predictive models is crucial to expand their use in clinical practice. Existing heatmap-based…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Kathryn Schutte , Olivier Moindrot , Paul Hérent , Jean-Baptiste Schiratti , Simon Jégou

In this paper, we propose a novel interpretation method tailored to histological Whole Slide Image (WSI) processing. A Deep Neural Network (DNN), inspired by Bag-of-Features models is equipped with a Multiple Instance Learning (MIL) branch…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Magdalini Paschali , Muhammad Ferjad Naeem , Walter Simson , Katja Steiger , Martin Mollenhauer , Nassir Navab

Parkinson's disease (PD) is a common and complex neurodegenerative disorder with 5 stages in the Hoehn and Yahr scaling. Given the heterogeneity of PD, it is challenging to classify early stages 1 and 2 and detect brain function…

Neurons and Cognition · Quantitative Biology 2022-07-22 Xueqi Guo , Sule Tinaz , Nicha C. Dvornek

In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical…

Computational Engineering, Finance, and Science · Computer Science 2013-12-10 Peyman Mohammadi , Abdolreza Hatamlou , Mohammad Masdari

PPINtonus is a system for the early detection of Parkinson's Disease (PD) utilizing deep-learning tonal analysis, providing a cost-effective and accessible alternative to traditional neurological examinations. Partnering with the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-06 Varun Reddy

Deep learning (DL) has gained popularity in recent years as an effective tool for classifying the current health and predicting the future of industrial equipment. However, most DL models have black-box components with an underlying…

Machine Learning · Computer Science 2023-08-22 Hao Lu , Austin M. Bray , Chao Hu , Andrew T. Zimmerman , Hongyi Xu

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

While deep neural networks (DNN) have become an effective computational tool, the prediction results are often criticized by the lack of interpretability, which is essential in many real-world applications such as health informatics.…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Mengnan Du , Ninghao Liu , Qingquan Song , Xia Hu

In this work, we use a deep learning framework for simultaneous classification and regression of Parkinson disease diagnosis based on MR-Images and personal information (i.e. age, gender). We intend to facilitate and increase the confidence…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Soheil Esmaeilzadeh , Yao Yang , Ehsan Adeli
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