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Deformable image registration (DIR), aiming to find spatial correspondence between images, is one of the most critical problems in the domain of medical image analysis. In this paper, we present a novel, generic, and accurate diffeomorphic…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Yifan Wu , Tom Z. Jiahao , Jiancong Wang , Paul A. Yushkevich , M. Ani Hsieh , James C. Gee

Standard Patlak plot is widely used to describe FDG kinetics for dynamic PET imaging. Whole-body Patlak parametric imaging remains constrained due to the need for a full-time input function. Here, we demonstrate the Relative Patlak (RP)…

Medical Physics · Physics 2024-07-29 Siqi Li , Yasser G. Abdelhafez , Lorenzo Nardo , Simon R. Cherry , Ramsey D. Badawi , Guobao Wang

An important topic in medical research is the process of improving the images obtained from medical devices. As a consequence, there is also a need to improve medical image resolution and analysis. Another issue in this field is the large…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Elena-Simona Apostol , Ciprian-Octavian Truică

We propose a novel approach to image segmentation based on combining implicit spline representations with deep convolutional neural networks. This is done by predicting the control points of a bivariate spline function whose zero-set…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Oliver J. D. Barrowclough , Georg Muntingh , Varatharajan Nainamalai , Ivar Stangeby

Photoacoustic tomography (PAT) offers optical contrast, whereas magnetic resonance imaging (MRI) excels in imaging soft tissue and organ anatomy. The fusion of PAT with MRI holds promising application prospects due to their complementary…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yutian Zhong , Jinchuan He , Zhichao Liang , Shuangyang Zhang , Qianjin Feng , Lijun Lu , Li Qi

The inversion of linear systems is a fundamental step in many inverse problems. Computational challenges exist when trying to invert large linear systems, where limited computing resources mean that only part of the system can be kept in…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-09-05 Yushan Gao , Thomas Blumensath

Modern deep learning reconstruction algorithms generate impressively realistic scans from sparse inputs, but can often produce significant inaccuracies. This makes it difficult to provide statistically guaranteed claims about the true state…

Machine Learning · Computer Science 2025-09-29 Matt Y Cheung , Tucker J Netherton , Laurence E Court , Ashok Veeraraghavan , Guha Balakrishnan

We propose a software platform that integrates methods and tools for multi-objective parameter auto- tuning in tissue image segmentation workflows. The goal of our work is to provide an approach for improving the accuracy of nucleus/cell…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-09 Luis F. R. Taveira , Tahsin Kurc , Alba C. M. A. Melo , Jun Kong , Erich Bremer , Joel H. Saltz , George Teodoro

We introduce a method for fast estimation of data-adapted, spatio-temporally dependent regularization parameter-maps for variational image reconstruction, focusing on total variation (TV)-minimization. Our approach is inspired by recent…

Image-guided surgery collocates patient-specific data with the physical environment to facilitate surgical decision making in real-time. Unfortunately, these guidance systems commonly become compromised by intraoperative soft-tissue…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Morgan Ringel , Jon Heiselman , Winona Richey , Ingrid Meszoely , William Jarnagin , Michael Miga

In this work, we apply a kinetic version of a bounded confidence consensus model to biomedical segmentation problems. In the presented approach, time-dependent information on the microscopic state of each particle/pixel includes its space…

Image and Video Processing · Electrical Eng. & Systems 2024-06-17 Raffaella Fiamma Cabini , Anna Pichiecchio , Alessandro Lascialfari , Silvia Figini , Mattia Zanella

The reconstruction of dynamic positron emission tomography (PET) images from noisy projection data is a significant but challenging problem. In this paper, we introduce an unsupervised learning approach, Non-negative Implicit Neural…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Chaozhi Zhang , Wenxiang Ding , Roy Y. He , Xiaoqun Zhang , Qiaoqiao Ding

Anatomically guided PET reconstruction using MRI information has been shown to have the potential to improve PET image quality. However, these improvements are limited to PET scans with paired MRI information. In this work we employed a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Weijie Gan , Huidong Xie , Carl von Gall , Günther Platsch , Michael T. Jurkiewicz , Andrea Andrade , Udunna C. Anazodo , Ulugbek S. Kamilov , Hongyu An , Jorge Cabello

Atomic resolution STEM images often suffer from noise due to low electron doses and instrument imperfections, hence it is challenging to obtain critical structural details required for material analysis. To address the problem, we propose a…

Materials Science · Physics 2024-12-18 Z. Awan , J. Shabeer , U. Saleem , S. Mehmood , T. Qadeer

Precision medicine seeks to discover an optimal personalized treatment plan and thereby provide informed and principled decision support, based on the characteristics of individual patients. With recent advancements in medical imaging, it…

Methodology · Statistics 2023-04-26 Xinyi Li , Michael R. Kosorok

Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain imaging and neuroscience discovery, making the methods attractive for porting to a…

Neural and Evolutionary Computing · Computer Science 2014-02-20 Sergey M. Plis , Devon R. Hjelm , Ruslan Salakhutdinov , Vince D. Calhoun

Image stacks provide invaluable 3D information in various biological and pathological imaging applications. Fourier ptychographic microscopy (FPM) enables reconstructing high-resolution, wide field-of-view image stacks without z-stack…

Simulation of atomic resolution image formation in scanning transmission electron microscopy can require significant computation times using traditional methods. A recently developed method, termed plane-wave reciprocal-space interpolated…

Computational Physics · Physics 2017-07-07 Alan Pryor , Colin Ophus , Jianwei Miao

This work aims efficiently estimating the posterior distribution of kinetic parameters for dynamic positron emission tomography (PET) imaging given a measurement of time of activity curve. Considering the inherent information loss from…

Medical Physics · Physics 2023-10-25 Xiaofeng Liu , Thibault Marin , Tiss Amal , Jonghye Woo , Georges El Fakhri , Jinsong Ouyang

Patlak model is widely used in 18F-FDG dynamic positron emission tomography (PET) imaging, where the estimated parametric images reveal important biochemical and physiology information. Because of better noise modeling and more information…

Medical Physics · Physics 2020-09-15 Nuobei Xie , Kuang Gong , Ning Guo , Zhixing Qin , Jianan Cui , Zhifang Wu , Huafeng Liu , Quanzheng Li