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This paper discusses the fundamental principles of causal inference - the area of statistics that estimates the effect of specific occurrences, treatments, interventions, and exposures on a given outcome from experimental and observational…

Methodology · Statistics 2021-12-03 Francesca Dominici , Falco J. Bargagli-Stoffi , Fabrizia Mealli

Predicting the effect of interventions with many possible variations, e.g., therapeutic content that affects mental health outcomes or an earnings call transcript that drives movement in share price, is useful across several domains.…

Machine Learning · Computer Science 2026-05-27 Nikita Dhawan , Arnav Paruthi , Andrew Kim , Lovedeep Gondara , Jekaterina Novikova , Chris J. Maddison

A class of causal effect functionals requires integration over conditional densities of continuous variables, as in mediation effects and nonparametric identification in causal graphical models. Estimating such densities and evaluating the…

Methodology · Statistics 2026-02-26 Xiaxian Ou , Razieh Nabi

Recent developments enable the quantification of causal control given a structural causal model (SCM). This has been accomplished by introducing quantities which encode changes in the entropy of one variable when intervening on another.…

Machine Learning · Computer Science 2024-02-20 Francisco N. F. Q. Simoes , Mehdi Dastani , Thijs van Ommen

Causal structure learning with data from multiple contexts carries both opportunities and challenges. Opportunities arise from considering shared and context-specific causal graphs enabling to generalize and transfer causal knowledge across…

Machine Learning · Computer Science 2024-10-29 Martin Rabel , Wiebke Günther , Jakob Runge , Andreas Gerhardus

Causal inference requires evaluating models on balanced distributions between treatment and control groups, while training data often exhibits imbalance due to historical decision-making policies. Most conventional statistical methods…

Machine Learning · Statistics 2025-11-21 Akira Tanimoto

Classical machine learning techniques often struggle with overfitting and unreliable predictions when exposed to novel conditions. Introducing causality into the modelling process offers a promising way to mitigate these challenges by…

Computational Engineering, Finance, and Science · Computer Science 2025-05-28 David Zapata Gonzalez , Marcel Meyer , Oliver Mueller

This paper proposes an approach facilitating co-design of causal graphs between subject matter experts and statistical modellers. Modern causal analysis starting with formulation of causal graphs provides benefits for robust analysis and…

Methodology · Statistics 2025-05-02 Eli Y. Kling

Causal discovery, the task of inferring causal structure from data, has the potential to uncover mechanistic insights from biological experiments, especially those involving perturbations. However, causal discovery algorithms over larger…

Machine Learning · Computer Science 2025-04-01 Menghua Wu , Yujia Bao , Regina Barzilay , Tommi Jaakkola

Causal discovery aims to extract qualitative causal knowledge in the form of causal graphs from data. Because causal ground truth is rarely known in the real world, simulated data plays a vital role in evaluating the performance of the…

Machine Learning · Computer Science 2025-12-17 Rebecca J. Herman , Jonas Wahl , Urmi Ninad , Jakob Runge

Recurrent events, including cardiovascular events, are commonly observed in biomedical studies. Researchers must understand the effects of various treatments on recurrent events and investigate the underlying mediation mechanisms by which…

Methodology · Statistics 2025-07-08 Yan-Lin Chen , Yan-Hong Chen , Pei-Fang Su , Huang-Tz Ou , An-Shun Tai

Clinical decisions to treat and diagnose patients are affected by implicit biases formed by racism, ableism, sexism, and other stereotypes. These biases reflect broader systemic discrimination in healthcare and risk marginalizing already…

Machine Learning · Computer Science 2025-01-29 Kara Liu , Russ Altman , Vasilis Syrgkanis

Causal inference is a central goal across many scientific disciplines. Over the past several decades, three major frameworks have emerged to formalize causal questions and guide their analysis: the potential outcomes framework, structural…

Statistics Theory · Mathematics 2026-02-12 Linbo Wang , Thomas Richardson , James Robins

Though the topic of causal inference is typically considered in the context of classical statistical models, recent years have seen great interest in extending causal inference techniques to quantum and generalized theories. Causal…

Logic in Computer Science · Computer Science 2023-11-16 Isaac Friend , Aleks Kissinger

Disparities in health or well-being experienced by minority groups can be difficult to study using the traditional exposure-outcome paradigm in causal inference, since potential outcomes in variables such as race or sexual minority status…

Methodology · Statistics 2025-01-22 Andy A. Shen , Elina Visoki , Ran Barzilay , Samuel D. Pimentel

The COVID-19 pandemic has spurred a large amount of observational studies reporting linkages between the risk of developing severe COVID-19 or dying from it, and sex and gender. By reviewing a large body of related literature and conducting…

Causal discovery has been widely studied, yet many existing methods rely on strong assumptions or fall into two extremes: either depending on costly interventional signals or partial ground truth as strong priors, or adopting purely data…

Machine Learning · Computer Science 2026-03-24 Wenbo Xu , Yue He , Yunhai Wang , Xingxuan Zhang , Kun Kuang , Yueguo Chen , Peng Cui

A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for…

Discrimination discovery from data is an important task aiming at identifying patterns of illegal and unethical discriminatory activities against protected-by-law groups, e.g., ethnic minorities. While any legally-valid proof of…

Databases · Computer Science 2017-03-10 Francesco Bonchi , Sara Hajian , Bud Mishra , Daniele Ramazzotti

Causality is a central concept in a wide range of research areas, yet there is still no universally agreed axiomatisation of causality. We view causality both as an extension of probability theory and as a study of \textit{what happens when…

Artificial Intelligence · Computer Science 2024-06-07 Junhyung Park , Simon Buchholz , Bernhard Schölkopf , Krikamol Muandet