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Related papers: Unfolding as Quantum Annealing

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The presence of a bias field, encoding some information about the target state, can enhance the performance of quantum optimization methods. Here we investigate the effect of such a bias field on the outcome of quantum annealing sampling,…

Quantum Physics · Physics 2022-10-19 Tobias Graß

RNAs self-interact through hydrogen-bond base-pairing between nucleotides and fold into specific, stable structures that substantially govern their biochemical behaviour. Experimental characterization of these structures remains difficult,…

Quantum Physics · Physics 2023-05-02 Tristan Zaborniak , Juan Giraldo , Hausi Müller , Hosna Jabbari , Ulrike Stege

Quantum annealing aims at solving optimization problems of practical relevance using quantum-computing hardware. Problems of interest are typically formulated in terms of quadratic unconstrained binary optimization (QUBO) Hamiltonians.…

We present a quantum annealing-based solution method for topology optimization (TO). In particular, we consider TO in a more general setting, i.e., applied to structures of continuum domains where designs are represented as distributed…

Numerical Analysis · Mathematics 2023-01-30 Zisheng Ye , Xiaoping Qian , Wenxiao Pan

The D-Wave quantum annealers make it possible to obtain high quality solutions of NP-hard problems by mapping a problem in a QUBO (quadratic unconstrained binary optimization) or Ising form to the physical qubit connectivity structure on…

Quantum Physics · Physics 2022-12-29 Elijah Pelofske , Georg Hahn , Hristo Djidjev

Critical decision-making issues in science, engineering, and industry are based on combinatorial optimization; however, its application is inherently limited by the NP-hard nature of the problem. A specialized paradigm of analogue quantum…

Quantum Physics · Physics 2026-02-04 Rudraksh Sharma , Ravi Katukam , Arjun Nagulapally

In this paper, we review some features of quantum annealing and related topics from viewpoints of statistical physics, condensed matter physics, and computational physics. We can obtain a better solution of optimization problems in many…

Disordered Systems and Neural Networks · Physics 2017-08-23 Shu Tanaka , Ryo Tamura

We investigate the use of quantum computing algorithms on real quantum hardware to tackle the computationally intensive task of feature selection for light-weight medical image datasets. Feature selection is often formulated as a k of n…

Quantum Physics · Physics 2025-02-27 Merlin A. Nau , Luca A. Nutricati , Bruno Camino , Paul A. Warburton , Andreas K. Maier

Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

Diagnosing the minimal set of faults capable of explaining a set of given observations, e.g., from sensor readouts, is a hard combinatorial optimization problem usually tackled with artificial intelligence techniques. We present the mapping…

Systems of linear equations are employed almost universally across a wide range of disciplines, from physics and engineering to biology, chemistry and statistics. Traditional solution methods such as Gaussian elimination become very time…

Quantum Physics · Physics 2019-01-23 Michael L Rogers , Robert L Singleton

Quantum annealers, such as the device built by D-Wave Systems, Inc., offer a way to compute solutions of NP-hard problems that can be expressed in Ising or QUBO (quadratic unconstrained binary optimization) form. Although such solutions are…

Quantum Physics · Physics 2022-10-27 Aaron Barbosa , Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

Molecular Docking (MD) is an important step of the drug discovery process which aims at calculating the preferred position and shape of one molecule to a second when they are bound to each other. During such analysis, 3D representations of…

Quantum Physics · Physics 2021-07-30 Kevin Mato , Riccardo Mengoni , Daniele Ottaviani , Gianluca Palermo

This paper presents a new method to reduce the optimization of a pseudo-Boolean function to QUBO problem which can be solved by quantum annealer. The new method has two aspects, one is coefficient optimization and the other is variable…

Cryptography and Security · Computer Science 2022-11-21 Anpeng Zhang , Xiutao Feng

Quantum annealing has emerged as a powerful platform for simulating and optimizing classical and quantum Ising models. Quantum annealers, like other quantum and/or analog computing devices, are susceptible to nonidealities including…

Quantum Physics · Physics 2024-10-15 Kevin Chern , Kelly Boothby , Jack Raymond , Pau Farré , Andrew D. King

Recent studies on quantum computing algorithms focus on excavating features of quantum computers which have potential for contributing to computational model enhancements. Among various approaches, quantum annealing methods effectively…

Quantum Physics · Physics 2021-11-02 Sun Woo Park , Hyunju Lee , Byung Chun Kim , Youngho Woo , Kyungtaek Jun

Quadratic unconstrained binary optimization (QUBO) has become the standard format for optimization using quantum computers, i.e., for both the quantum approximate optimization algorithm (QAOA) and quantum annealing (QA). We present a…

Quantum Physics · Physics 2022-04-26 Thomas Gabor , Marian Lingsch Rosenfeld , Sebastian Feld , Claudia Linnhoff-Popien

Quantum computing is developing fast. Real world applications are within reach in the coming years. One of the most promising areas is combinatorial optimisation, where the Quadratic Unconstrained Binary Optimisation (QUBO) problem…

Quantum Physics · Physics 2020-07-06 Frank Phillipson , Irina Chiscop

In this paper, we propose a quantum algorithm that supports a real-valued higher-order unconstrained binary optimization (HUBO) problem. This algorithm is based on the Grover adaptive search that originally supported HUBO with integer…

Signal Processing · Electrical Eng. & Systems 2023-02-17 Masaya Norimoto , Ryuhei Mori , Naoki Ishikawa

The quadratic unconstrained binary optimization (QUBO) problem arises in diverse optimization applications ranging from Ising spin problems to classical problems in graph theory and binary discrete optimization. The use of preprocessing to…

Artificial Intelligence · Computer Science 2017-05-29 Fred Glover , Mark Lewis , Gary Kochenberger