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Graphical model selection is a seemingly impossible task when many pairs of variables are never jointly observed; this requires inference of conditional dependencies with no observations of corresponding marginal dependencies. This…

Statistics Theory · Mathematics 2023-02-16 Giuseppe Vinci , Gautam Dasarathy , Genevera I. Allen

In this paper, we consider the problem of estimating multiple graphical models simultaneously using the fused lasso penalty, which encourages adjacent graphs to share similar structures. A motivating example is the analysis of brain…

Machine Learning · Computer Science 2014-01-03 Sen Yang , Zhaosong Lu , Xiaotong Shen , Peter Wonka , Jieping Ye

Graph sampling via crawling has become increasingly popular and important in the study of measuring various characteristics of large scale complex networks. While powerful, it is known to be challenging when the graph is loosely connected…

Social and Information Networks · Computer Science 2014-05-21 Junzhou Zhao , John C. S. Lui , Don Towsley , Pinghui Wang , Xiaohong Guan

Identifying unusual brain activity is a crucial task in neuroscience research, as it aids in the early detection of brain disorders. It is common to represent brain networks as graphs, and researchers have developed various graph-based…

Machine Learning · Computer Science 2024-10-04 Sadaf Sadeghian , Xiaoxiao Li , Margo Seltzer

We consider a two-sample hypothesis testing problem, where the distributions are defined on the space of undirected graphs, and one has access to only one observation from each model. A motivating example for this problem is comparing the…

Brain networks has attracted the interests of many neuroscientists. From functional MRI (fMRI) data, statistical tools have been developed to recover brain networks. However, the dimensionality of whole-brain fMRI, usually in hundreds of…

Methodology · Statistics 2014-04-08 Xi Luo

While many multiple graph inference methodologies operate under the implicit assumption that an explicit vertex correspondence is known across the vertex sets of the graphs, in practice these correspondences may only be partially or…

Machine Learning · Statistics 2017-09-29 Vince Lyzinski

Performing statistical analyses on collections of graphs is of import to many disciplines, but principled, scalable methods for multi-sample graph inference are few. Here we describe an "omnibus" embedding in which multiple graphs on the…

Methodology · Statistics 2019-06-27 Keith Levin , Avanti Athreya , Minh Tang , Vince Lyzinski , Youngser Park , Carey E. Priebe

Two-sample tests for multivariate data and especially for non-Euclidean data are not well explored. This paper presents a novel test statistic based on a similarity graph constructed on the pooled observations from the two samples. It can…

Methodology · Statistics 2024-08-12 Hao Chen , Jerome H. Friedman

Networks represent relationships between entities in many complex systems, spanning from online social interactions to biological cell development and brain connectivity. In many cases, relationships between entities are unambiguously…

Social and Information Networks · Computer Science 2018-01-23 Ivan Brugere , Brian Gallagher , Tanya Y. Berger-Wolf

In applications of graphical models, we typically have more information than just the samples themselves. A prime example is the estimation of brain connectivity networks based on fMRI data, where in addition to the samples themselves, the…

Machine Learning · Statistics 2017-04-21 Yunqi Bu , Johannes Lederer

Data produced by resting-state functional Magnetic Resonance Imaging are widely used to infer brain functional connectivity networks. Such networks correlate neural signals to connect brain regions, which consist in groups of dependent…

Methodology · Statistics 2023-12-05 Hanâ Lbath , Alexander Petersen , Sophie Achard

Measuring functional connectivity from fMRI is important in understanding processing in cortical networks. However, because brain's connection pattern is complex, currently used methods are prone to produce false connections. We introduce…

Neurons and Cognition · Quantitative Biology 2020-06-23 Tiger w. Lin , Giri P. Krishnan , Maxim Bazhenov , Terrence J. Sejnowski

Gene interaction graphs aim to capture various relationships between genes and can represent decades of biology research. When trying to make predictions from genomic data, those graphs could be used to overcome the curse of dimensionality…

The correlation matrix of massive biomedical data (e.g. gene expression or neuroimaging data) often exhibits a complex and organized, yet latent graph topological structure. We propose a two step procedure that first detects the latent…

Applications · Statistics 2017-08-09 Shuo Chen , Jian Kang , Yishi Xing , Yunpeng Zhao , Don Milton

Recent research in neuroimaging has focused on assessing associations between genetic variants that are measured on a genomewide scale and brain imaging phenotypes. A large number of works in the area apply massively univariate analyses on…

Network analysis of human brain connectivity is critically important for understanding brain function and disease states. Embedding a brain network as a whole graph instance into a meaningful low-dimensional representation can be used to…

Machine Learning · Computer Science 2018-07-26 Ye Liu , Lifang He , Bokai Cao , Philip S. Yu , Ann B. Ragin , Alex D. Leow

Given a pair of graphs with the same number of vertices, the inexact graph matching problem consists in finding a correspondence between the vertices of these graphs that minimizes the total number of induced edge disagreements. We study…

Machine Learning · Statistics 2020-07-06 Jesús Arroyo , Daniel L. Sussman , Carey E. Priebe , Vince Lyzinski

Feature extraction and dimension reduction for networks is critical in a wide variety of domains. Efficiently and accurately learning features for multiple graphs has important applications in statistical inference on graphs. We propose a…

Applications · Statistics 2021-06-23 Shangsi Wang , Jesús Arroyo , Joshua T. Vogelstein , Carey E. Priebe

Gaussian Graphical Models provide a convenient framework for representing dependencies between variables. Recently, this tool has received a high interest for the discovery of biological networks. The literature focuses on the case where a…

Methodology · Statistics 2010-05-13 Julien Chiquet , Yves Grandvalet , Christophe Ambroise