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A source of high-energy photons, ions, and positrons can be attained with the interaction of ultra-intense femtosecond laser pulses with advanced nanostructured targets. We present and characterise a numerical model that mimics the foam…
Positron Emission Tomography (PET) is a widely-used imaging modality for medical research and clinical diagnosis. Here we demonstrate, through detailed experiments and simulations, an exploration of the benefits of exploiting the quantum…
Dynamic positron emission tomography (dPET) image reconstruction is extremely challenging due to the limited counts received in individual frame. In this paper, we propose a spatial-temporal convolutional primal dual network (STPDnet) for…
Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applications. The interpretation of FDG-PET data requires…
In computed tomography (CT), reducing the number of projection views is an effective strategy to lower radiation exposure and/or improve temporal resolution. However, this often results in severe aliasing artifacts and loss of structural…
In this work, we developed a novel text-guided image synthesis technique which could generate realistic tau PET images from textual descriptions and the subject's MR image. The generated tau PET images have the potential to be used in…
Standard dual-energy computed tomography (CT) uses two different X-ray energies to obtain energy-dependent tissue attenuation information to allow quantitative material decomposition. The combined use of dual-energy CT and positron emission…
The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…
We continue studies of the uncertainty quantification problem in emission tomographies such as PET or SPECT when additional multimodal data (e.g., anatomical MRI images) are available. To solve the aforementioned problem we adapt the…
Attenuation and scatter correction (AC) is crucial for quantitative Positron Emission Tomography (PET) imaging. Recently, direct application of AC in the image domain using deep learning approaches has been proposed for the hybrid PET/MR…
To correct for respiratory motion in PET imaging, an interpretable and unsupervised deep learning technique, FlowNet-PET, was constructed. The network was trained to predict the optical flow between two PET frames from different breathing…
Deep learning has significantly advanced PET image re-construction, achieving remarkable improvements in image quality through direct training on sinogram or image data. Traditional methods often utilize masks for inpainting tasks, but…
Low-dose PET offers a valuable means of minimizing radiation exposure in PET imaging. However, the prevalent practice of employing additional CT scans for generating attenuation maps (u-map) for PET attenuation correction significantly…
The present paper proposes a novel computational method for parametric imaging of nuclear medicine data. The mathematical procedure is general enough to work for compartmental models of diverse complexity and is effective in the…
Strong semantic representations improve the convergence and generation quality of diffusion and flow models. Existing approaches largely rely on external models, which require separate training, operate on misaligned objectives, and exhibit…
Computational fluid dynamics (CFD) provides high-fidelity simulations of fluid flows but remains computationally expensive for many-query applications. In recent years deep learning (DL) has been used to construct data-driven fluid-dynamic…
Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…
Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of a wide range of neurological diseases. Positron emission tomography (PET) with radiolabeled water (15O-water) is considered the…
The distribution of produced isotopes during proton therapy can be imaged with Positron Emission Tomography (PET) to verify dose delivery. However, biological washout, driven by tissue-dependent processes such as perfusion and cellular…
Diagnosing pre-existing heart diseases early in life is important as it helps prevent complications such as pulmonary hypertension, heart rhythm problems, blood clots, heart failure and sudden cardiac arrest. To identify such diseases,…