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Networks have in recent years emerged as an invaluable tool for describing and quantifying complex systems in many branches of science. Recent studies suggest that networks often exhibit hierarchical organization, where vertices divide into…

Machine Learning · Statistics 2008-11-05 Aaron Clauset , Cristopher Moore , M. E. J. Newman

Cycling is a promising solution to unsustainable urban transport systems. However, prevailing bicycle network development follows a slow and piecewise process, without taking into account the structural complexity of transportation…

Physics and Society · Physics 2022-04-27 Michael Szell , Sayat Mimar , Tyler Perlman , Gourab Ghoshal , Roberta Sinatra

As a result of a hundred million years of evolution, living animals have adapted extremely well to their ecological niche. Such adaptation implies species-specific interactions with their immediate environment by processing sensory cues and…

Disordered Systems and Neural Networks · Physics 2022-04-28 Tom Birkoben , Hermann Kohlstedt

The competition for resources is a defining feature of microbial communities. In many contexts, from soils to host-associated communities, highly diverse microbes are organized into metabolic groups or guilds with similar resource…

Physics and Society · Physics 2025-05-05 Xiaowen Chen , Kyle Crocker , Seppe Kuehn , Aleksandra M. Walczak , Thierry Mora

Topology transcends boundaries that conventionally delineate physical, biological and engineering sciences. Our ability to mathematically describe topology, combined with our access to precision tracking and manipulation approaches, has…

Biological Physics · Physics 2021-01-01 Anupam Sengupta

Bacteriophages are central to microbial ecosystems for balancing bacterial populations and promoting evolution by applying strong selection pressure. Here we review some of the known aspects that modulate phage-bacteria interaction in a way…

Populations and Evolution · Quantitative Biology 2023-04-12 Namiko Mitarai , Anastasios Marantos , Kim Sneppen

Chemical reaction networks underpin biological and physical phenomena across scales, from microbial interactions to planetary atmosphere dynamics. Bacterial communities exhibit complex competitive interactions for resources, human organs…

Molecular Networks · Quantitative Biology 2026-01-08 Jorge Reyes , Jörn Dunkel

What determines whether an organism or collective will survive under particular conditions? This question is asked across the life sciences when determining adaptive fit, developing efficacious treatments for diseases, and assessing the…

Quantitative Methods · Quantitative Biology 2026-05-19 Connor McShaffrey , Randall D. Beer

Previous work has shown that species interacting in an ecosystem and actors transacting in an economic context may have notable similarities in behavior. However, the specific mechanism that may underlie similarities in nature and human…

Physics and Society · Physics 2011-10-04 Serguei Saavedra , Felix Reed-Tsochas , Brian Uzzi

An ongoing debate in ecology concerns the impacts of ecological drift and selection on community assembly. Here, we show that there is a sharp phase transition in diverse ecological communities between a selection dominated regime (the…

Populations and Evolution · Quantitative Biology 2015-06-16 Charles K. Fisher , Pankaj Mehta

Networks are widely used in the biological, physical, and social sciences as a concise mathematical representation of the topology of systems of interacting components. Understanding the structure of these networks is one of the outstanding…

Data Analysis, Statistics and Probability · Physics 2007-06-21 M. E. J. Newman , E. A. Leicht

Deciphering the control principles of metabolism and its interaction with other cellular functions is central to biomedicine and biotechnology. Yet, understanding the efficient control of metabolic fluxes remains elusive for large-scale…

Molecular Networks · Quantitative Biology 2015-09-04 Georg Basler , Zoran Nikoloski , Abdelhalim Larhlimi , Albert-László Barabási , Yang-Yu Liu

Local coexistence of species in large ecosystems is traditionally explained within the broad framework of niche theory. However, its rationale hardly justifies rich biodiversity observed in nearly homogeneous environments. Here we consider…

Populations and Evolution · Quantitative Biology 2021-11-17 Deepak Gupta , Stefano Garlaschi , Samir Suweis , Sandro Azaele , Amos Maritan

Biological systems excel at building spatial structures on scales ranging from nanometers to kilometers and exhibit temporal patterning from milliseconds to years. One approach that nature has taken to accomplish this relies on the…

Cell Behavior · Quantitative Biology 2009-11-10 Herbert Levine , Eshel Ben-Jacob

The regulation of metabolic activity by tuning enzyme expression levels is crucial to sustain cellular growth in changing environments. Metabolic networks are often studied at steady state using constraint-based models and optimization…

Molecular Networks · Quantitative Biology 2014-10-24 Steffen Waldherr , Diego A. Oyarzún , Alexander Bockmayr

Sequence differences between the strains of bacteria comprising host-associated and environmental microbiota may play a role in community assembly and influence the resilience of microbial communities to disturbances. Tools for…

A procedure to characterize chaotic dynamical systems with concepts of complex networks is pursued, in which a dynamical system is mapped onto a network. The nodes represent the regions of space visited by the system, while edges represent…

Statistical Mechanics · Physics 2011-12-20 Ernesto P. Borges , Daniel O. Cajueiro , Roberto F. S. Andrade

Food webs are networks describing who is eating whom in an ecological community. By now it is clear that many aspects of food-web structure are reproducible across diverse habitats, yet little is known about the driving force behind this…

Populations and Evolution · Quantitative Biology 2007-05-23 A. G. Rossberg , H. Matsuda , T. Amemiya , K. Itoh

Competition is a major force in structuring ecological communities. The strength of competition can be measured using the concept of a niche. A niche comprises the set of requirements of an organism in terms of habitat, environment and…

Probability · Mathematics 2007-05-23 N. Lanchier , C. Neuhauser

High-throughput sequencing techniques such as metagenomic and metatranscriptomic technologies allow cataloging of functional characteristics of microbial community members as well as their taxonomic identity. Such studies have found that a…

Populations and Evolution · Quantitative Biology 2019-06-24 Lee Worden