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Programmable electron-beam scanning offers new opportunities to improve dose efficiency and suppress scan-induced artifacts in scanning transmission electron microscopy. Here, we systematically benchmark the impact of non-raster…

Lightweight deep learning models offer substantial reductions in computational cost and environmental impact, making them crucial for scientific applications. We present a lightweight CycleGAN for modality transfer in fluorescence…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Mohammad Soltaninezhad , Yashar Rouzbahani , Jhonatan Contreras , Rohan Chippalkatti , Daniel Kwaku Abankwa , Christian Eggeling , Thomas Bocklitz

Endoscopic optical imaging using a single multimode fiber (MMF) has emerged as a promising approach for highly compact, minimally invasive, and high-resolution imaging. Unlike conventional fiber bundles, MMF-based endomicroscopes exploit…

Label-free microscopy exploits light scattering to obtain a three-dimensional image of biological tissues. However, light propagation is affected by aberrations and multiple scattering, which drastically degrade the image quality and limit…

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

A distinct feature of pancreatic ductal adenocarcinoma (PDAC) is a prominent tumor microenvironment (TME) with remarkable cellular and spatial heterogeneity that meaningfully impacts disease biology and treatment resistance. The dynamic…

Electron ptychography has seen a recent surge of interest for phase sensitive imaging at atomic or near-atomic resolution. However, applications are so far mainly limited to radiation-hard samples because the required doses are too high for…

Computational Physics · Physics 2017-02-21 Philipp Michael Pelz , Wen Xuan Qiu , Robert Bücker , Günther Kassier , R. J. Dwayne Miller

Flexible and fast control of the phase and amplitude of coherent light, enabled by digital micromirror devices (DMDs) and spatial light modulators (SLMs), has been a driving force for recent advances in optical tweezers, nonlinear…

Optics · Physics 2021-07-07 Ruslan Röhrich , Femius Koenderink , Stefan Witte , Lars Loetgering

The popular VQ-VAE models reconstruct images through learning a discrete codebook but suffer from a significant issue in the rapid quality degradation of image reconstruction as the compression rate rises. One major reason is that a higher…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Xinmiao Lin , Yikang Li , Jenhao Hsiao , Chiuman Ho , Yu Kong

Lightsheet microscopy is a powerful 3-D imaging technique that addresses limitations of traditional optical and confocal microscopy but suffers from a low penetration depth and reduced image quality at greater depths. Multiview lightsheet…

Image and Video Processing · Electrical Eng. & Systems 2025-03-21 Marek Wodzinski , Henning Müller

Purpose: To achieve automatic hyperparameter estimation for the joint recovery of quantitative MR images, we propose a Bayesian formulation of the reconstruction problem that incorporates the signal model. Additionally, we investigate the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Shuai Huang , James J. Lah , Jason W. Allen , Deqiang Qiu

Accurate single photoelectron (SPE) characterization of photosensors is essential for controlling systematic uncertainties in low-light neutrino and dark matter detectors. We present a compact laboratory setup for the characterization of…

Instrumentation and Detectors · Physics 2026-03-24 Matthias Raphael Stock , Hans Th. J. Steiger , Ulrike Fahrendholz , Luca Schweizer , Lothar Oberauer

High-quality panoramic images with a Field of View (FoV) of 360{\deg} are essential for contemporary panoramic computer vision tasks. However, conventional imaging systems come with sophisticated lens designs and heavy optical components.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Qi Jiang , Shaohua Gao , Yao Gao , Kailun Yang , Zhonghua Yi , Hao Shi , Lei Sun , Kaiwei Wang

Fourier Ptychographic Microscopy (FPM) is a recent technique to overcome the diffraction limit of a low numerical aperture (NA) objective lens by algorithmic post-processing of several lower resolved images. It can increase the…

Semi-supervised learning has been employed to alleviate the need for extensive labeled data for histopathology image segmentation, but existing methods struggle with noisy pseudo-labels due to ambiguous gland boundaries and morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Thien Nguyen , Daisuke Kihara , Tianyang Wang , Xingjian Li , Min Xu

X-ray imaging is a fundamental tool of routine clinical diagnosis. Fluoroscopic imaging can further acquire X-ray images at video frame rates, thus enabling non-invasive in-vivo motion studies of joints, gastrointestinal tract, etc. For…

Image and Video Processing · Electrical Eng. & Systems 2018-10-22 Jacky C. K. Chow , Derek Lichti , Kathleen Ang , Gregor Kuntze , Gulshan Sharma , Janet Ronsky

Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…

Quantitative Methods · Quantitative Biology 2025-11-03 Surajit Das , Pavel Zun

Photogalvanic effect (PGE) occurring in noncentrosymmetric materials enables the generation of the open-circuit voltage that is much larger than the bandgap, making it rather attractive in solar cells. However, the magnitude of the PGE…

Applied Physics · Physics 2020-08-11 Juan Zhao , Yibin Hu , Yiqun Xie , Lei Zhang , Yin Wang

Diffusion Transformer models can generate images with remarkable fidelity and detail, yet training them at ultra-high resolutions remains extremely costly due to the self-attention mechanism's quadratic scaling with the number of image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Noam Issachar , Guy Yariv , Sagie Benaim , Yossi Adi , Dani Lischinski , Raanan Fattal

We introduce a new multi-dimensional nonlinear embedding -- Piecewise Flat Embedding (PFE) -- for image segmentation. Based on the theory of sparse signal recovery, piecewise flat embedding with diverse channels attempts to recover a…

Computer Vision and Pattern Recognition · Computer Science 2018-08-13 Chaowei Fang , Zicheng Liao , Yizhou Yu
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