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Electrocardiogram (ECG) data collection during emergency situations is challenging, making ECG data generation an efficient solution for dealing with highly imbalanced ECG training datasets. In this paper, we propose a novel approach for…

Signal Processing · Electrical Eng. & Systems 2023-06-06 Nour Neifar , Achraf Ben-Hamadou , Afef Mdhaffar , Mohamed Jmaiel , Bernd Freisleben

Recently, Generative Adversarial Networks (GANs) have emerged as a popular alternative for modeling complex high dimensional distributions. Most of the existing works implicitly assume that the clean samples from the target distribution are…

Machine Learning · Statistics 2019-02-14 Mohammadreza Soltani , Swayambhoo Jain , Abhinav Sambasivan

Next-generation sequencing technologies provide a revolutionary tool for generating gene expression data. Starting with a fixed RNA sample, they construct a library of millions of differentially abundant short sequence tags or "reads",…

Quantitative Methods · Quantitative Biology 2014-05-13 Dimitrios V. Vavoulis , Julian Gough

With the advance of high-throughput sequencing technologies, it has become feasible to investigate the influence of the entire spectrum of sequencing variations on complex human diseases. Although association studies utilizing the new…

Methodology · Statistics 2025-08-19 Ming Li , Zihuai He , Min Zhang , Xiaowei Zhan , Changshuai Wei , Robert C Elston , Qing Lu

Large-scale statistical analysis of data sets associated with genome sequences plays an important role in modern biology. A key component of such statistical analyses is the computation of $p$-values and confidence bounds for statistics…

Applications · Statistics 2011-01-06 Peter J. Bickel , Nathan Boley , James B. Brown , Haiyan Huang , Nancy R. Zhang

The development of coalescent theory paved the way to statistical inference from population genetic data. In the genomic era, however, coalescent models are limited due to the complexity of the underlying ancestral recombination graph. The…

Populations and Evolution · Quantitative Biology 2021-06-30 Julien Y. Dutheil

Acquiring annotated data at scale with rare diseases or conditions remains a challenge. It would be extremely useful to have a method that controllably synthesizes images that can correct such underrepresentation. Assuming a proper latent…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Spyridon Thermos , Xiao Liu , Alison O'Neil , Sotirios A. Tsaftaris

Graph representation of structured data can facilitate the extraction of stereoscopic features, and it has demonstrated excellent ability when working with deep learning systems, the so-called Graph Neural Networks (GNNs). Choosing a…

Machine Learning · Computer Science 2021-01-27 Yingfang Yuan , Wenjun Wang , George M. Coghill , Wei Pang

This paper presents a new framework for analysing forensic DNA samples using probabilistic genotyping. Specifically it presents a mathematical framework for specifying and combining the steps in producing forensic casework electropherograms…

Applications · Statistics 2018-02-28 Robert George Cowell

Here we present a structural similarity index measure (SSIM) guided conditional Generative Adversarial Network (cGAN) that generatively performs image-to-image (i2i) synthesis to generate photo-accurate protein channels in multiplexed…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Jillur Rahman Saurav , Mohammad Sadegh Nasr , Paul Koomey , Michael Robben , Manfred Huber , Jon Weidanz , Bríd Ryan , Eytan Ruppin , Peng Jiang , Jacob M. Luber

We propose a new architecture and training methodology for generative adversarial networks. Current approaches attempt to learn the transformation from a noise sample to a generated data sample in one shot. Our proposed generator…

Machine Learning · Computer Science 2018-11-26 Safwan Hossain , Kiarash Jamali , Yuchen Li , Frank Rudzicz

With the advance in genome sequencing technology, the lengths of deoxyribonucleic acid (DNA) sequencing results are rapidly increasing at lower prices than ever. However, the longer lengths come at the cost of a heavy computational burden…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-12 Seongyeon Park , Junguk Hong , Jaeyong Song , Hajin Kim , Youngsok Kim , Jinho Lee

Graph-structured data is ubiquitous in scientific domains, where models often face imbalanced learning settings. In imbalanced regression, domain preferences focus on specific target value ranges that represent the most scientifically…

Machine Learning · Computer Science 2025-07-15 Brenda Nogueira , Gabe Gomes , Meng Jiang , Nitesh V. Chawla , Nuno Moniz

Many applications in different domains produce large amount of time series data. Making accurate forecasting is critical for many decision makers. Various time series forecasting methods exist which use linear and nonlinear models…

Machine Learning · Computer Science 2019-07-19 Ümit Çavuş Büyükşahin , Şeyda Ertekin

Gene transcription is a highly stochastic and dynamic process. As a result, the mRNA copy number of a given gene is heterogeneous both between cells and across time. We present a framework to model gene transcription in populations of cells…

Quantitative Methods · Quantitative Biology 2017-01-10 Justine Dattani , Mauricio Barahona

Generating large-scale samples of stationary random fields is of great importance in the fields such as geomaterial modeling and uncertainty quantification. Traditional methodologies based on covariance matrix decomposition have the…

Methodology · Statistics 2022-08-23 Bin Zhu , Jiahao Liu , Zhengshou Lai , Tao Qian

Historical map collections are highly diverse in style, scale, and geographic focus, often consisting of many single-sheet documents. Yet most work in map recognition focuses on specialist models tailored to homogeneous map series. In…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Remi Petitpierre

We propose a novel approach to improve the reproducibility of neuroimaging results by converting statistic maps across different functional MRI pipelines. We make the assumption that pipelines used to compute fMRI statistic maps can be…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Elodie Germani , Camille Maumet , Elisa Fromont

Having a precise knowledge of the dispersal ability of a population in a heterogeneous environment is of critical importance in agroecology and conservation biology as it can provide management tools to limit the effects of pests or to…

Populations and Evolution · Quantitative Biology 2015-03-19 L. Roques , E. Walker , P. Franck , S. Soubeyrand , E. K. Klein

Reconstructing components of a genomic mixture from data obtained by means of DNA sequencing is a challenging problem encountered in a variety of applications including single individual haplotyping and studies of viral communities.…

Genomics · Quantitative Biology 2019-11-14 Ziqi Ke , Haris Vikalo