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Heterogeneity is an unwanted variation when analyzing aggregated datasets from multiple sources. Though different methods have been proposed for heterogeneity adjustment, no systematic theory exists to justify these methods. In this work,…

Methodology · Statistics 2016-02-18 Jianqing Fan , Han Liu , Weichen Wang , Ziwei Zhu

In this paper, we present a Generative Adversarial Network (GAN) machine learning model to interpolate irregularly distributed measurements across the spatial domain to construct a smooth radio frequency map (RFMap) and then perform…

Machine Learning · Computer Science 2021-11-25 Kuldeep S. Gill , Son Nguyen , Myo M. Thein , Alexander M. Wyglinski

Genetic variation in human populations is influenced by geographic ancestry due to spatial locality in historical mating and migration patterns. Spatial population structure in genetic datasets has been traditionally analyzed using either…

Populations and Evolution · Quantitative Biology 2016-10-26 Anand Bhaskar , Adel Javanmard , Thomas A. Courtade , David Tse

Whole and targeted sequencing of human genomes is a promising, increasingly feasible tool for discovering genetic contributions to risk of complex diseases. A key step is calling an individual's genotype from the multiple aligned short read…

Applications · Statistics 2012-06-29 Baiyu Zhou , Alice S. Whittemore

Motivation: Genomic data analyses such as Genome-Wide Association Studies (GWAS) or Hi-C studies are often faced with the problem of partitioning chromosomes into successive regions based on a similarity matrix of high-resolution,…

Statistics Theory · Mathematics 2019-02-06 Christophe Ambroise , Alia Dehman , Pierre Neuvial , Guillem Rigaill , Nathalie Vialaneix

This study presents domain-informed genetic superposition programming (DIGSP), a symbolic regression framework tailored for engineering systems governed by separable physical mechanisms. DIGSP partitions the input space into domain-specific…

Neural and Evolutionary Computing · Computer Science 2025-09-29 Mohammad Sadegh Khorshidi , Navid Yazdanjue , Hassan Gharoun , Mohammad Reza Nikoo , Fang Chen , Amir H. Gandomi

Traditional Linear Genetic Programming (LGP) algorithms are based only on the selection mechanism to guide the search. Genetic operators combine or mutate random portions of the individuals, without knowing if the result will lead to a…

Neural and Evolutionary Computing · Computer Science 2017-04-05 Léo Françoso Dal Piccol Sotto , Vinícius Veloso de Melo

Genome assembly is a prominent problem studied in bioinformatics, which computes the source string using a set of its overlapping substrings. Classically, genome assembly uses assembly graphs built using this set of substrings to compute…

Data Structures and Algorithms · Computer Science 2024-09-24 Saumya Talera , Parth Bansal , Shabnam Khan , Shahbaz Khan

Viruses represent the most abundant biological entities on Earth and play a pivotal role in microbial ecosystems, yet, as prominent human pathogens, they are closely linked to human morbidity and mortality. Accurate identification of viral…

Databases · Computer Science 2026-04-30 Wenxi Zhu , Wensheng Gan , Zhenlian Qi

Air Traffic Control (ATC) is a complex safety critical environment. A tower controller would be making many decisions in real-time to sequence aircraft. While some optimization tools exist to help the controller in some airports, even in…

Neural and Evolutionary Computing · Computer Science 2018-03-01 Jiangjun Tang , Hussein A. Abbass

We revisit human motion synthesis, a task useful in various real world applications, in this paper. Whereas a number of methods have been developed previously for this task, they are often limited in two aspects: focusing on the poses while…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Jingbo Wang , Sijie Yan , Bo Dai , Dahua LIn

An important feature of all real-world networks is that the network structure changes over time. Due to this dynamic nature, it becomes difficult to propose suitable growth models that can explain the various important characteristic…

Social and Information Networks · Computer Science 2016-02-17 Sandipan Sikdar , Niloy Ganguly , Animesh Mukherjee

While generative modeling has become prevalent across numerous research fields, its integration into the realm of image retrieval remains largely unexplored and underjustified. In this paper, we present a novel methodology, reframing image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Yidan Zhang , Ting Zhang , Dong Chen , Yujing Wang , Qi Chen , Xing Xie , Hao Sun , Weiwei Deng , Qi Zhang , Fan Yang , Mao Yang , Qingmin Liao , Jingdong Wang , Baining Guo

The Gaussian graphical model is a widely used tool for learning gene regulatory networks with high-dimensional gene expression data. Most existing methods for Gaussian graphical models assume that the data are homogeneous, i.e., all samples…

Methodology · Statistics 2018-05-08 Bochao Jia , Faming Liang

Signal decomposition and multiscale signal analysis provide many useful tools for time-frequency analysis. We proposed a random feature method for analyzing time-series data by constructing a sparse approximation to the spectrogram. The…

Signal Processing · Electrical Eng. & Systems 2023-03-17 Nicholas Richardson , Hayden Schaeffer , Giang Tran

In semi-supervised segmentation, capturing meaningful semantic structures from unlabeled data is essential. This is particularly challenging in histopathology image analysis, where objects are densely distributed. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Meilong Xu , Xiaoling Hu , Shahira Abousamra , Chen Li , Chao Chen

This paper proposes to use set features for detecting anomalies in samples that consist of unusual combinations of normal elements. Many leading methods discover anomalies by detecting an unusual part of a sample. For example,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Niv Cohen , Issar Tzachor , Yedid Hoshen

The first step in any genome assembly algorithm entails the conversion from the domain of strings and overlaps to the language of graphs and paths, typically using one of the two conventional methods: de Bruijn graphs or overlap graphs.…

Genomics · Quantitative Biology 2026-04-27 Anton Bankevich

Human and animal tissues consist of heterogeneous cell types that organize and interact in highly structured manners. Bulk and single-cell sequencing technologies remove cells from their original microenvironments, resulting in a loss of…

Quantitative Methods · Quantitative Biology 2022-02-08 Boxiang Liu , Yanjun Li , Liang Zhang

Background: With the fast development of next generation sequencing technologies, increasing numbers of genomes are being de novo sequenced and assembled. However, most are in fragmental and incomplete draft status, and thus it is often…

Genomics · Quantitative Biology 2020-02-28 Binghang Liu , Yujian Shi , Jianying Yuan , Xuesong Hu , Hao Zhang , Nan Li , Zhenyu Li , Yanxiang Chen , Desheng Mu , Wei Fan
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