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Accurate and reliable predictions of infectious disease dynamics can be valuable to public health organizations that plan interventions to decrease or prevent disease transmission. A great variety of models have been developed for this…

Machine Learning · Statistics 2018-07-04 Evan L. Ray , Nicholas G. Reich

Seasonal influenza forecasting is critical for public health and individual decision making. We investigate whether the inclusion of data about influenza activity in neighboring states can improve point predictions and distribution…

Applications · Statistics 2024-08-26 Gabrielle Thivierge , Aaron Rumack , F. William Townes

The annual influenza outbreak leads to significant public health and economic burdens making it desirable to have prompt and accurate probabilistic forecasts of the disease spread. The United States Centers for Disease Control and…

Applications · Statistics 2025-08-29 Spencer Wadsworth , Jarad Niemi

Seasonal influenza causes on average 425,000 hospitalizations and 32,000 deaths per year in the United States. Forecasts of influenza-like illness (ILI) -- a surrogate for the proportion of patients infected with influenza -- support public…

Applications · Statistics 2024-01-02 Ningxi Wei , Xinze Zhou , Wei-Min Huang , Thomas McAndrew

The characteristics of influenza seasons varies substantially from year to year, posing challenges for public health preparation and response. Influenza forecasting is used to inform seasonal outbreak response, which can in turn potentially…

Applications · Statistics 2022-03-16 Nutcha Wattanachit , Evan L. Ray , Thomas C. McAndrew , Nicholas G. Reich

Infectious diseases are one of the leading causes of morbidity and mortality around the world; thus, forecasting their impact is crucial for planning an effective response strategy. According to the Centers for Disease Control and…

Populations and Evolution · Quantitative Biology 2015-05-18 Kyle S. Hickmann , Geoffrey Fairchild , Reid Priedhorsky , Nicholas Generous , James M. Hyman , Alina Deshpande , Sara Y. Del Valle

Seasonal influenza epidemics cause consistent, considerable, widespread loss annually in terms of economic burden, morbidity, and mortality. With access to accurate and reliable forecasts of a current or upcoming influenza epidemic's…

Populations and Evolution · Quantitative Biology 2016-02-17 Logan C. Brooks , David C. Farrow , Sangwon Hyun , Ryan J. Tibshirani , Roni Rosenfeld

Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

Machine Learning · Computer Science 2024-09-04 Michael Morris

We present a machine learning-based methodology capable of providing real-time ("nowcast") and forecast estimates of influenza activity in the US by leveraging data from multiple data sources including: Google searches, Twitter microblogs,…

Applications · Statistics 2016-02-17 Mauricio Santillana , Andre T. Nguyen , Mark Dredze , Michael J. Paul , John S. Brownstein

Public health surveillance systems often fail to detect emerging infectious diseases, particularly in resource limited settings. By integrating relevant clinical and internet-source data, we can close critical gaps in coverage and…

Applications · Statistics 2019-03-05 Kai Liu , Ravi Srinivasan , Lauren Ancel Meyers

Timely and robust influenza incidence forecasting is critical for public health decision-making. This paper presents MAESTRO (Multi-modal Adaptive Estimation for Temporal Respiratory Disease Outbreak), a novel, unified framework that…

Machine Learning · Computer Science 2025-09-22 Hong Liu , Kerui Cen , Yanxing Chen , Zige Liu , Dong Chen , Zifeng Yang , Chitin Hon

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

Social and Information Networks · Computer Science 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

Forecasting the hospitalizations caused by the Influenza virus is vital for public health planning so that hospitals can be better prepared for an influx of patients. Many forecasting methods have been used in real-time during the Influenza…

Machine Learning · Computer Science 2022-06-22 Majd Al Aawar , Ajitesh Srivastava

Ensemble forecasts have become a cornerstone of large-scale disease response, underpinning decision making at agencies such as the US Centers for Disease Control and Prevention (CDC). Their growing use reflects the goal of combining…

Applications · Statistics 2026-01-23 Carson Dudley , Marisa Eisenberg

Background: Over the past few decades, numerous forecasting methods have been proposed in the field of epidemic forecasting. Such methods can be classified into different categories such as deterministic vs. probabilistic, comparative…

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

In this paper, we present a new approach to time series forecasting. Time series data are prevalent in many scientific and engineering disciplines. Time series forecasting is a crucial task in modeling time series data, and is an important…

Machine Learning · Computer Science 2020-01-24 Neo Wu , Bradley Green , Xue Ben , Shawn O'Banion

Forecasting influenza in a timely manner aids health organizations and policymakers in adequate preparation and decision making. However, effective influenza forecasting still remains a challenge despite increasing research interest. It is…

In this manuscript, we use meteorological information in Galicia (Spain) to propose a novel approach to predict the incidence of influenza. Our approach extends the GLS methods in the multivariate framework to functional regression models…

Influenza forecasting in the United States (US) is complex and challenging for reasons including substantial spatial and temporal variability, nested geographic scales of forecast interest, and heterogeneous surveillance participation. Here…

Applications · Statistics 2019-10-01 Dave Osthus , Kelly R Moran
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