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Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

Applications · Statistics 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

Seasonal influenza is a sometimes surprisingly impactful disease, causing thousands of deaths per year along with much additional morbidity. Timely knowledge of the outbreak state is valuable for managing an effective response. The current…

Populations and Evolution · Quantitative Biology 2020-07-01 Reid Priedhorsky , Ashlynn R. Daughton , Martha Barnard , Fiona O'Connell , Dave Osthus

Much traditional statistical modelling assumes that the outcome variables of interest are independent of each other when conditioned on the explanatory variables. This assumption is strongly violated in the case of infectious diseases,…

Populations and Evolution · Quantitative Biology 2019-11-28 Timothy Kinyanjui , Thomas House

The seasonality of respiratory diseases (common cold, influenza, etc.) is a well-known phenomenon studied from ancient times. The development of predictive models is still not only an actual unsolved problem of mathematical epidemiology but…

Populations and Evolution · Quantitative Biology 2014-04-28 Eugene B. Postnikov , Dmitry V. Tatarenkov

Ensembling is a powerful technique for improving the accuracy of machine learning models, with methods like stacking achieving strong results in tabular tasks. In time series forecasting, however, ensemble methods remain underutilized, with…

Machine Learning · Computer Science 2025-11-20 Nathanael Bosch , Oleksandr Shchur , Nick Erickson , Michael Bohlke-Schneider , Caner Türkmen

Influenza A is responsible for 290,000 to 650,000 respiratory deaths a year, though this estimate is an improvement from years past due to improvements in sanitation, healthcare practices, and vaccination programs. In this study, we perform…

Machine Learning · Computer Science 2025-07-29 Edmund F. Agyemang , Hansapani Rodrigo , Vincent Agbenyeavu

Influenza is an infectious disease with the potential to become a pandemic, and hence, forecasting its prevalence is an important undertaking for planning an effective response. Research has found that web search activity can be used to…

Machine Learning · Computer Science 2021-05-27 Michael Morris , Peter Hayes , Ingemar J. Cox , Vasileios Lampos

We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…

Populations and Evolution · Quantitative Biology 2019-06-21 Inbar Seroussi , Nir Levy , Daniela Paolotti , Nir Sochen , Elad Yom-Tov

Epidemics of influenza are major public health concerns. Since influenza prediction always relies on the weekly clinical or laboratory surveillance data, typically the weekly Influenza-like illness (ILI) rate series, accurate…

Machine Learning · Computer Science 2021-10-28 Siyue Yang , Yukun Bao

Accurate forecasts of disease outbreaks are critical for effective public health responses, management of healthcare surge capacity, and communication of public risk. There are a growing number of powerful forecasting methods that fall into…

In this work, we propose an ensemble forecasting approach based on randomized neural networks. Improved randomized learning streamlines the fitting abilities of individual learners by generating network parameters in accordance with the…

Machine Learning · Computer Science 2021-07-12 Grzegorz Dudek , Paweł Pełka

Loss reserving generally focuses on identifying a single model that can generate superior predictive performance. However, different loss reserving models specialise in capturing different aspects of loss data. This is recognised in…

Methodology · Statistics 2024-06-04 Benjamin Avanzi , Yanfeng Li , Bernard Wong , Alan Xian

Increased availability of epidemiological data, novel digital data streams, and the rise of powerful machine learning approaches have generated a surge of research activity on real-time epidemic forecast systems. In this paper, we propose…

Social and Information Networks · Computer Science 2021-09-15 Ioanna Miliou , Xinyue Xiong , Salvatore Rinzivillo , Qian Zhang , Giulio Rossetti , Fosca Giannotti , Dino Pedreschi , Alessandro Vespignani

Subseasonal-to-seasonal forecasting is crucial for public health, disaster preparedness, and agriculture, and yet it remains a particularly challenging timescale to predict. We explore the use of an interpretable AI-informed model analog…

Atmospheric and Oceanic Physics · Physics 2026-04-06 Jacob B. Landsberg , Matthew Newman , Elizabeth A. Barnes

Early prediction of the prevalence of influenza reduces its impact. Various studies have been conducted to predict the number of influenza-infected people. However, these studies are not highly accurate especially in the distant future such…

Machine Learning · Computer Science 2019-07-08 Kenjiro Kondo , Akihiko Ishikawa , Masashi Kimura

Each year, seasonal influenza epidemics cause hundreds of thousands of deaths worldwide and put high loads on health care systems. A main concern for resource planning is the risk of exceptionally severe epidemics. Taking advantage of…

Applications · Statistics 2021-06-29 Maud Thomas , Holger Rootzén

This paper proposes a sequential ensemble methodology for epidemic modeling that integrates discrete-time Hawkes processes (DTHP) and Susceptible-Exposed-Infectious-Removed (SEIR) models. Motivated by the need for accurate and reliable…

Applications · Statistics 2026-01-21 Dhorasso Temfack , Jason Wyse

Influenza, an infectious disease, causes many deaths worldwide. Predicting influenza victims during epidemics is an important task for clinical, hospital, and community outbreak preparation. On-line user-generated contents (UGC), primarily…

Computers and Society · Computer Science 2021-04-15 Taichi Murayama , Nobuyuki Shimizu , Sumio Fujita , Shoko Wakamiya , Eiji Aramaki

We consider the problem of individual-specific medication level recommendation (initiation, removal, increase, or decrease) for asthma sufferers. Asthma is one of the most common chronic diseases in both adults and children, affecting 8% of…

Applications · Statistics 2017-05-22 Curtis B Storlie , Megan E Branda , Michael R Gionfriddo , Nilay D Shah , Matthew A Rank

A central challenge in every field of biology is to use existing measurements to predict the outcomes of future experiments. In this work, we consider the wealth of antibody inhibition data against variants of the influenza virus. Due to…

Quantitative Methods · Quantitative Biology 2023-07-27 Tal Einav , Rong Ma