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Age estimation is an important yet very challenging problem in computer vision. Existing methods for age estimation usually apply a divide-and-conquer strategy to deal with heterogeneous data caused by the non-stationary aging process.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Wanhua Li , Jiwen Lu , Jianjiang Feng , Chunjing Xu , Jie Zhou , Qi Tian

Understanding brain connectivity in a network-theoretic context has shown much promise in recent years. This type of analysis identifies brain organisational principles, bringing a new perspective to neuroscience. At the same time, large…

Neural and Evolutionary Computing · Computer Science 2016-11-28 Sarah Parisot , Jonathan Passerat-Palmbach , Markus D. Schirmer , Boris Gutman

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Brain age gap estimation (BrainAGE) is a promising imaging-derived biomarker of neurobiological aging and disease risk, yet current approaches rely predominantly on T1-weighted structural MRI (T1w), overlooking functional vascular changes…

Image and Video Processing · Electrical Eng. & Systems 2025-12-10 Jordan Jomsky , Kay C. Igwe , Zongyu Li , Yiren Zhang , Max Lashley , Tal Nuriel , Andrew Laine , Jia Guo

The study of signatures of aging in terms of genomic biomarkers can be uniquely helpful in understanding the mechanisms of aging and developing models to accurately predict the age. Prior studies have employed gene expression and DNA…

Genomics · Quantitative Biology 2021-11-08 Salman Mohamadi , Gianfranco. Doretto , Nasser M. Nasrabadi , Donald A. Adjeroh

Predicting an individual's aging trajectory is a central challenge in preventative medicine and bioinformatics. While machine learning models can predict chronological age from biomarkers, they often fail to capture the dynamic,…

Machine Learning · Computer Science 2025-08-14 Nazira Dunbayeva , Yulong Li , Yutong Xie , Imran Razzak

Interactions between the brain and body are of fundamental importance for human behavior and health. Functional magnetic resonance imaging (fMRI) captures whole-brain activity noninvasively, and modeling how fMRI signals interact with…

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

Optimization and Control · Mathematics 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Degeneration and adaptation are two competing sides of the same coin called resilience in the progressive processes of brain aging or diseases. Degeneration accumulates during brain aging and other cerebral activities, causing structural…

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with artificial intelligence has been previously proposed for diagnostic support, but most of these…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Pierrick Coupé , Boris Mansencal , José V. Manjón , Patrice Péran , Wassilios G. Meissner , Thomas Tourdias , Vincent Planche

Extracting time-varying latent variables from computational cognitive models is a key step in model-based neural analysis, which aims to understand the neural correlates of cognitive processes. However, existing methods only allow…

Machine Learning · Computer Science 2025-09-01 Ti-Fen Pan , Jing-Jing Li , Bill Thompson , Anne Collins

Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

Data-driven methods for battery lifetime prediction are attracting increasing attention for applications in which the degradation mechanisms are poorly understood and suitable training sets are available. However, while advanced machine…

Machine Learning · Computer Science 2021-12-21 Peter M. Attia , Kristen A. Severson , Jeremy D. Witmer

Regression problems with time-series predictors are common in banking and many other areas of application. In this paper, we use multi-head attention networks to develop interpretable features and use them to achieve good predictive…

Machine Learning · Computer Science 2022-05-26 Tianjie Wang , Jie Chen , Joel Vaughan , Vijayan N. Nair

Recent studies in neuroscience show great potential of functional brain networks constructed from fMRI data for popularity modeling and clinical predictions. However, existing functional brain networks are noisy and unaware of downstream…

Machine Learning · Computer Science 2021-07-26 Xuan Kan , Hejie Cui , Ying Guo , Carl Yang

Deep learning can provide rapid brain age estimation based on brain magnetic resonance imaging (MRI). However, most studies use one neural network to extract the global information from the whole input image, ignoring the local fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Sheng He , P. Ellen Grant , Yangming Ou

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

This paper considers neural representation through the lens of active inference, a normative framework for understanding brain function. It delves into how living organisms employ generative models to minimize the discrepancy between…

Neurons and Cognition · Quantitative Biology 2023-10-24 Giovanni Pezzulo , Leo D'Amato , Francesco Mannella , Matteo Priorelli , Toon Van de Maele , Ivilin Peev Stoianov , Karl Friston

Motivation: Since susceptibility to diseases increases with age, studying aging gains importance. Analyses of gene expression or sequence data, which have been indispensable for investigating aging, have been limited to studying genes and…

Computational Engineering, Finance, and Science · Computer Science 2013-07-15 Fazle Elahi Faisal , Tijana Milenkovic