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Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

Soft Condensed Matter · Physics 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Simulating protein-membrane interactions is an important and dynamic area of research. A proper definition of electrostatic forces on membrane surfaces is necessary for developing electromechanical models of protein-membrane interactions.…

Analysis of PDEs · Mathematics 2013-09-24 Michael Mikucki , Y. C. Zhou

Liquid wetting of a surface is omnipresent in nature and the advance of micro-fabrication and assembly techniques in recent years offers increasing ability to control this phenomenon. Here, we identify how surface roughness influences the…

Unlike their model membrane counterparts, biological membranes are richly decorated with a heterogeneous assembly of membrane proteins. These proteins are so tightly packed that their excluded area interactions can alter the free energy…

Biological Physics · Physics 2017-08-23 Martin Lindén , Pierre Sens , Rob Phillips

The variation of energies associated with soft matter interfaces where surface inhomogeneities are present. These energies include the total bending and splay energy, the variable surface tension energy, a coupling energy between the total…

Soft Condensed Matter · Physics 2016-12-02 Prerna Gera , David Salac

We present a nonequlibrium approach for the study of a flexible bilayer whose two components induce distinct curvatures. In turn, the two components are interconverted by an externally promoted reaction. Phase separation of the two species…

Soft Condensed Matter · Physics 2009-11-11 Ramon Reigada , Javier Buceta , Katja Lindenberg

We investigate the effect on biomembrane mechanical properties due to the presence an external potential for a non-conductive non-compressible membrane surrounded by different electrolytes. By solving the Debye-Huckel and Laplace equations…

Soft Condensed Matter · Physics 2007-06-13 Tobias Ambjornsson , Michael A. Lomholt , Per Lyngs Hansen

We consider how membrane fluctuations can modify the miscibility of lipid mixtures, that is to say how the phase diagram of a boundary-constrained membrane is modified when the membrane is allowed to fluctuate freely in the case of zero…

Soft Condensed Matter · Physics 2015-06-11 David S. Dean , V. Adrian Parsegian , R. Podgornik

We consider membranes as fluid deformable surface and allow for higher order geometric terms in the bending energy. The evolution equations are derived and numerically solved using surface finite elements. The higher order geometric terms…

Soft Condensed Matter · Physics 2024-12-19 Jan Magnus Sischka , Ingo Nitschke , Axel Voigt

The shapes of cell membranes are largely regulated by membrane associated, curvature active, proteins. We use a numerical model of the membrane with elongated membrane inclusions, recently developed by us, which posses spontaneous…

Biological Physics · Physics 2013-02-08 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

We report, for the first time, some experimental observations regarding a new type of long range interaction between rigid particles that prevails when they are suspended in an soft elastic gel. A denser particle submerges itself to a…

Soft Condensed Matter · Physics 2014-01-29 Aditi Chakrabarti , Manoj K. Chaudhury

An accurate description of the structure and dynamics of interfacial water is essential for phospholipid membranes, since it determines their function and their interaction with other molecules. Here we consider water confined in stacked…

Soft Condensed Matter · Physics 2018-11-16 Sotiris Samatas , Carles Calero , Fausto Martelli , Giancarlo Franzese

We theoretically explore fluidization of epithelial tissues by active T1 neighbor exchanges. We show that the geometry of cell-cell junctions encodes important information about the local features of the energy landscape, which we support…

Soft Condensed Matter · Physics 2018-08-31 Matej Krajnc , Sabyasachi Dasgupta , Primož Ziherl , Jacques Prost

We show that the short-scale elastic distortions that are excited in the vicinity of the joint between different lipidic membrane domains (at a scale of \~10 nm) may produce a "crease" from the point of view of the standard elastic…

Soft Condensed Matter · Physics 2007-05-23 Jean-Baptiste Fournier , Martine Ben Amar

A net force can arise on objects which lie in systems with complex energy partitions, even if the system is on average stationary. These forces are usually called fluctuation forces, as they arise due to the objects modifying the character…

Fluid Dynamics · Physics 2023-09-15 Daniel Putt , Rodolfo Ostilla-Mónico

Large-scale cellular transformations are triggered by subtle physical and structural changes in individual biomacromolecular and membrane components. A prototypical example of such an event is the orchestrated fusion of membranes within an…

Soft Condensed Matter · Physics 2023-10-02 Ashesh Ghosh , Andrew J. Spkaowitz

The dynamical properties and mechanical functions of amorphous materials are governed by their microscopic structures, particularly the elasticity of the interaction networks, which is generally complicated by structural heterogeneity. This…

Statistical Mechanics · Physics 2018-04-11 Le Yan

In our recent works, based on the structural studies on water and interfacial water (topmost water layer at the solute/water interface), hydration free energy is derived and utilized to investigate the physical origin of hydrophobic…

Chemical Physics · Physics 2018-11-14 Qiang Sun

We carry out Monte Carlo simulations of a colloidal fluid membrane composed of chiral rod-like viruses. The membrane is modeled by a triangular mesh of beads connected by bonds in which the bonds and beads are free to move at each Monte…

Soft Condensed Matter · Physics 2020-09-23 Lijie Ding , Robert A. Pelcovits , Thomas R. Powers

Shape transformations of epithelial tissues in three dimensions, which are crucial for embryonic development or in vitro organoid growth, can result from active forces generated within the cytoskeleton of the epithelial cells. How the…

Biological Physics · Physics 2024-12-23 Diana Khoromskaia , Guillaume Salbreux