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The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

Deep neural networks have demonstrated very promising performance on accurate segmentation of challenging organs (e.g., pancreas) in abdominal CT and MRI scans. The current deep learning approaches conduct pancreas segmentation by…

Cone-beam CT (CBCT)-based online adaptive radiotherapy calls for accurate auto-segmentation to reduce the time cost for physicians to edit contours. However, deep learning (DL)-based direct segmentation of CBCT images is a challenging task,…

In current clinical practice, noisy and artifact-ridden weekly cone-beam computed tomography (CBCT) images are only used for patient setup during radiotherapy. Treatment planning is done once at the beginning of the treatment using…

In recent years, Deep Learning (DL) has shown promising results in conducting AI tasks such as computer vision and image segmentation. Specifically, Convolutional Neural Network (CNN) models in DL have been applied to prevention,detection,…

This paper deals with segmentation of organs at risk (OAR) in head and neck area in CT images which is a crucial step for reliable intensity modulated radiotherapy treatment. We introduce a convolution neural network with encoder-decoder…

Abdominal organ and tumour segmentation has many important clinical applications, such as organ quantification, surgical planning, and disease diagnosis. However, manual assessment is inherently subjective with considerable inter- and…

Objective: Herein, a neural network-based liver segmentation algorithm is proposed, and its performance was evaluated using abdominal computed tomography (CT) images. Methods: A fully convolutional network was developed to overcome the…

Accurate segmentation of multiple organs of the head, neck, chest, and abdomen from medical images is an essential step in computer-aided diagnosis, surgical navigation, and radiation therapy. In the past few years, with a data-driven…

Automatic localization and segmentation of organs-at-risk (OAR) in CT are essential pre-processing steps in medical image analysis tasks, such as radiation therapy planning. For instance, the segmentation of OAR surrounding tumors enables…

Organ segmentation in CT volumes is an important pre-processing step in many computer assisted intervention and diagnosis methods. In recent years, convolutional neural networks have dominated the state of the art in this task. However,…

Objective: Automated segmentation tools are useful for calculating kidney volumes rapidly and accurately. Furthermore, these tools have the power to facilitate large-scale image-based artificial intelligence projects by generating input…

X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…

Accurate segmentation of organs from abdominal CT scans is essential for clinical applications such as diagnosis, treatment planning, and patient monitoring. To handle challenges of heterogeneity in organ shapes, sizes, and complex…

Differentiating between Intestinal Tuberculosis (ITB) and Crohn's Disease (CD) poses a significant clinical challenge due to their similar symptoms, clinical presentations, and imaging features. This study leverages Computed Tomography…

Next generation online and real-time adaptive radiotherapy workflows require precise particle transport simulations in sub-second times, which is unfeasible with current analytical pencil beam algorithms (PBA) or stochastic Monte Carlo (MC)…

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

Purpose: To present a high-performing, robust, and flexible deep learning pipeline for automatic segmentation of 30 organs-at-risk (OARs) in head and neck (H&N) cancer patients, using MRI, CT, or both. Method: We trained a segmentation…

Accurate segmentation of prostate and surrounding organs at risk is important for prostate cancer radiotherapy treatment planning. We present a fully automated workflow for male pelvic CT image segmentation using deep learning. The…