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We study the mathematical properties of a model of cell division structured by two variables, the size and the size increment, in the case of a linear growth rate and a self-similar fragmentation kernel. We first show that one can construct…

Analysis of PDEs · Mathematics 2019-03-13 Pierre Gabriel , Hugo Martin

We consider the system of reaction-diffusion equations proposed in [8] as a population dynamics model. The first equation stands for the population density and models the ecological effects, namely dispersion and growth with a Allee effect…

Analysis of PDEs · Mathematics 2018-01-23 Matthieu Alfaro , Arnaud Ducrot

We study a generic reaction-diffusion model for single-species population dynamics that includes reproduction, death, and competition. The population is assumed to be confined in a refuge beyond which conditions are so harsh that they lead…

Statistical Mechanics · Physics 2009-11-10 C. Escudero , J. Buceta , F. J. de la Rubia , Katja Lindenberg

We study a mathematical model of cell populations dynamics proposed by M. Rotenberg and investigated by M. Boulanouar. Here, a cell is characterized by her maturity and speed of maturation. The growth of cell populations is described by a…

Analysis of PDEs · Mathematics 2017-12-12 Adam Gregosiewicz

In this paper, we study the initial-boundary value problem of a repulsion Keller--Segel system with a logarithmic sensitivity modeling the reinforced random walk. By establishing an energy-dissipation identity, we prove the existence of…

Analysis of PDEs · Mathematics 2020-07-07 Jie Jiang

The variability in cell size of an isogenic population of Escherichia coli has been widely reported in experiment. The probability density function (PDF) of cell lengths has been variously described by exponential and lognormal functions.…

Cell Behavior · Quantitative Biology 2019-05-21 Chaitanya A. Athale

Multicellular systems play a key role in bioprocess and biomedical engineering. Cell ensembles encountered in these setups show phenotypic variability like size and biochemical composition. As this variability may result in undesired…

Systems and Control · Computer Science 2018-07-16 Armin Küper , Robert Dürr , Steffen Waldherr

Among the different computational approaches modelling the dynamics of isogenic cell populations, discrete stochastic models can describe with sufficient accuracy the evolution of small size populations. However, for a systematic and…

Molecular Networks · Quantitative Biology 2013-12-16 I Aviziotis , M Kavousanakis , I Bitsanis , A Boudouvis

In this work, we investigate the dynamics of a non-local model describing spontaneous cell polarisation. It consists in a drift-diffusion equation set in the half-space, with the coupling involving the trace value on the boundary. We…

Analysis of PDEs · Mathematics 2011-05-24 Vincent Calvez , Rhoda Hawkins , Nicolas Meunier , Raphael Voituriez

Cell division times in microbial populations display significant fluctuations, that impact the population growth rate in a non-trivial way. If fluctuations are uncorrelated among different cells, the population growth rate is predicted by…

Populations and Evolution · Quantitative Biology 2021-07-07 Simone Pigolotti

Cell competition is a quality control mechanism in tissues that results in the elimination of less fit cells. Over the past decade, the phenomenon of cell competition has been identified in many physiological and pathological contexts,…

Tissues and Organs · Quantitative Biology 2019-03-26 Daniel Gradeci , Anna Bove , Guillaume Charras , Alan R. Lowe , Shiladitya Banerjee

In this paper we deal with diffusive relaxation limits of nonlinear systems of Euler type modeling chemotactic movement of cells toward Keller--Segel type systems. The approximating systems are either hyperbolic--parabolic or…

Analysis of PDEs · Mathematics 2008-07-25 M. Di Francesco , D. Donatelli

We consider a system of two kinetic equations modelling a multicellular system : The first equation governs the dynamics of cells, whereas the second kinetic equation governs the dynamics of the chemoattractant. For this system, we first…

Analysis of PDEs · Mathematics 2019-07-30 Mohamed Khaladi , Nisrine Outada , Nicolas Vauchelet

Periodic reversals of the direction of motion in systems of self-propelled rod shaped bacteria enable them to effectively resolve traffic jams formed during swarming and maximize their swarming rate. In this paper, a connection is found…

Biological Physics · Physics 2015-03-17 Richard Gejji , Pavel M. Lushnikov , Mark Alber

A deterministic population dynamics model involving birth and death for a two-species system, comprising a wild-type and more resistant species competing via logistic growth, is subjected to two distinct stress environments designed to…

Biological Physics · Physics 2018-02-08 Marianne Bauer , Isabella R. Graf , Vudtiwat Ngampruetikorn , Greg J. Stephens , Erwin Frey

Radiation Therapy (XRT) is one of the most common cancer treatment methods. In this paper, a new mathematical model is proposed for the population dynamics of heterogeneous tumor cells following external beam radiation treatment. According…

Quantitative Methods · Quantitative Biology 2018-01-23 Amin Oroji , Shantia Yarahmadian , Sarkhosh Seddighi , Mohd Omar

We consider a two-species simple exclusion process on a periodic lattice. We use the method of matched asymptotics to derive evolution equations for the two population densities in the dilute regime, namely a cross-diffusion system of…

Mathematical Physics · Physics 2023-01-25 James Mason , Robert L Jack , Maria Bruna

In this paper we study the initial boundary value problem for the system $u_t-\Delta u^m=-\mbox{div}(u^{q}\nabla v),\ v_t-\Delta v+v=u$. This problem is the so-called Keller-Segel model with nonlinear diffusion. Our investigation reveals…

Analysis of PDEs · Mathematics 2020-12-18 Xiangsheng Xu

We investigate a model of cell division in which the length of telomeres within the cell regulate their proliferative potential. At each cell division the ends of linear chromosomes change and a cell becomes senescent when one or more of…

Cell Behavior · Quantitative Biology 2008-04-23 T. Antal , K. B. Blagoev , S. A. Trugman , S. Redner

A simple model of particle creation and annihilation in an isolated assembly of particles with conserved energy and fixed volume, the Cell Model, is formulated. With increasing time, particle number distribution, obtained by averaging over…

Nuclear Theory · Physics 2018-04-25 M. Gazdzicki , M. I. Gorenstein , A. Fronczak , P. Fronczak , M. Mackowiak-Pawlowska
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