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Originally developed to elucidate the mechanisms of natural selection in bacteria, the Luria-Delbr\"uck model assumed that cells are intrinsically capable of dividing an unlimited number of times. This assumption however, is not true for…

Populations and Evolution · Quantitative Biology 2015-11-17 Ignacio A Rodriguez-Brenes , Dominik Wodarz , Natalia L. Komarova

We study the global strong solutions to a 3-dimensional parabolic-hyperbolic Keller-Segel model with initial data close to a stable equilibrium with perturbations belonging to $L^2(\mathbb R^3)\times H^1(\mathbb{R}^3)$. We obtain global…

Analysis of PDEs · Mathematics 2012-11-01 Chao Deng , Tong Li

This paper continues our survey about the mean-field derivation of the two-dimensional signal-dependent Keller-Segel system studied in [1]. Therefore, we consider the same system of moderately interacting particles as before. The difference…

Probability · Mathematics 2026-05-18 Lukas Bol , Li Chen

We discuss a simple model of co-evolution. In order to emphasise the effect of interaction between individuals the entire population is subjected to the same physical environment. Species are emergent structures and extinction, origination…

Statistical Mechanics · Physics 2007-05-23 Kim Christensen , Simone A. di Collobiano , Matt Hall , Henrik J. Jensen

In any ecosystem, the conditions of the environment and the characteristics of the species that inhabit it are entangled, co-evolving in space and time. We introduce a model that couples active agents with a dynamic environment, interpreted…

Populations and Evolution · Quantitative Biology 2025-12-10 G. Briozzo , G. J. Sibona , F. Peruani

Single-cell experiments revealed substantial variability in generation times, growth rates but also in birth and division sizes between genetically identical cells. Understanding how these fluctuations determine the fitness of the…

Populations and Evolution · Quantitative Biology 2025-03-24 Arthur Genthon

A hybrid stochastic individual-based model of proliferating cells with chemotaxis is presented. The model is expressed by a branching diffusion process coupled to a partial differential equation describing concentration of a chemotactic…

Probability · Mathematics 2023-02-16 Radosław Wieczorek

A one-dimensional many-body model is established to mimic the charge distribution and dynamics in nonfullerene organic solar cells. Two essential issues are taken into account in the model: The alternating donor and acceptor structure and…

Materials Science · Physics 2018-12-05 Yao Yao

Individual cells exhibit specific proliferative responses to changes in microenvironmental conditions. Whether such potential is constrained by the cell density throughout the growth process is however unclear. Here, we identify a…

Solving population balance equations, we derive analytical steady-state cell size distributions for single-lineage experiments, such as the mother machine. These experiments are fundamentally different from batch cultures where populations…

Populations and Evolution · Quantitative Biology 2023-09-13 Arthur Genthon

It is well known that the different cell-division models, such as Timer, Sizer, and Adder, can be distinguished based on the correlations between different single-cell-level quantities such as birth-size, division-time, division-size, and…

Statistical Mechanics · Physics 2025-10-29 Vikas , Rahul Marathe , Anjan Roy

Isogenic Escherichia coli growing exponentially in a constant environment display large variation in growth-rates, division-sizes and generation-times. It is unclear how these seemingly random cell cycles can be reconciled with the precise…

Quantitative Methods · Quantitative Biology 2015-10-14 Mats Wallden , David Fange , Özden Baltekin , Johan Elf

In this review some simple models of asexual populations evolving on smooth landscapes are studied. The basic model is based on a cellular automaton, which is analyzed here in the spatial mean-field limit. Firstly, the evolution on a fixed…

Statistical Mechanics · Physics 2016-11-23 Franco Bagnoli , Michele Bezzi

We rigorously prove a form of disorder-resistance for a class of one-dimensional cellular automaton rules, including some that arise as boundary dynamics of two-dimensional solidification rules. Specifically, when started from a random…

Probability · Mathematics 2015-09-30 Janko Gravner , Alexander E. Holroyd

This paper is concerned with the global boundedness and blowup of solutions to the Keller-Segel system with density-dependent motility in a two-dimensional bounded smooth domain with Neumman boundary conditions. We show that if the motility…

Analysis of PDEs · Mathematics 2020-05-14 Hai-Yang Jin , Zhi-An Wang

Biological evolution in a sequence space with random fitnesses is studied within Eigen's quasispecies model. A strong selection limit is employed, in which the population resides at a single sequence at all times. Evolutionary trajectories…

Statistical Mechanics · Physics 2009-11-07 Joachim Krug , Christian Karl

We study a repulsion-diffusion equation with immigration, whose asymptotic behaviour is related to stability of long-term dynamics in spatial population models and other branching particle systems. We prove well-posedness and find sharp…

Analysis of PDEs · Mathematics 2023-11-17 Peter Koepernik

We consider a nonlinear coupled discrete-time model of population dynamics. This model describes the movement of populations within a heterogeneous landscape, where the growth of subpopulations are modelled by (possibly different) bounded…

Dynamical Systems · Mathematics 2024-05-08 Blake McGrane-Corrigan , Oliver Mason , Rafael de Andrade Moral

Auto-chemotaxis, the directed movement of cells along gradients in chemicals they secrete, is central to the formation of complex spatiotemporal patterns in biological systems. Since the introduction of the Keller--Segel model, numerous…

Soft Condensed Matter · Physics 2025-11-18 Henrik Weyer , David Muramatsu , Erwin Frey

Experimental studies of cell motility in culture have shown that under adequate conditions these living organisms possess the ability to organize themselves into complex structures. Such structures may exhibit a synergy that greatly…

Statistical Mechanics · Physics 2021-10-27 G. Nakamura , M. Badoual , E. Fabiani , C. Deroulers
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