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In computational pathology, the gigapixel scale of Whole-Slide Images (WSIs) necessitates their division into thousands of smaller patches. Analyzing these high-dimensional patch embeddings is computationally expensive and risks diluting…

Image and Video Processing · Electrical Eng. & Systems 2025-11-12 Saya Hashemian , Azam Asilian Bidgoli

Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods…

Computer Vision and Pattern Recognition · Computer Science 2014-04-29 Fayao Liu , Chunhua Shen

Masking strategies commonly employed in natural language processing are still underexplored in vision tasks such as concept learning, where conventional methods typically rely on full images. However, using masked images diversifies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Yuwei Sun , Lu Mi , Ippei Fujisawa , Ruiqiao Mei , Jimin Chen , Siyu Zhu , Ryota Kanai

Early detection of dementia is crucial to devise effective interventions. Comprehensive cognitive tests, while being the most accurate means of diagnosis, are long and tedious, thus limiting their applicability to a large population,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Anusha A. S. , Uma Ranjan , Medha Sharma , Siddharth Dutt

The insufficient supervision limit the performance of the deep supervised models for brain disease diagnosis. It is important to develop a learning framework that can capture more information in limited data and insufficient supervision. To…

Neurons and Cognition · Quantitative Biology 2024-10-10 Wenjing Gao , Yuanyuan Yang , Jianrui Wei , Xuntao Yin , Xinhan Di

Purpose: To investigate deep learning electrical properties tomography (EPT) for application on different simulated and in-vivo datasets including pathologies for obtaining quantitative brain conductivity maps. Methods: 3D patch-based…

The so-called Mild Cognitive Impairment (MCI) or cognitive loss appears in a previous stage before Alzheimer's Disease (AD), but it does not seem sufficiently severe to interfere in independent abilities of daily life, so it usually does…

Objective: We develop a deep learning framework based on the pre-trained Bidirectional Encoder Representations from Transformers (BERT) model using unstructured clinical notes from electronic health records (EHRs) to predict the risk of…

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

Alzheimer's disease (AD) and mild cognitive impairment (MCI), continue to be widely studied. While there is no consensus on whether MCIs actually "convert" to AD, the more important question is not whether MCIs convert, but what is the best…

Neurons and Cognition · Quantitative Biology 2015-05-28 Yaman Aksu , David J. Miller , George Kesidis , Don C. Bigler , Qing X. Yang

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Mahdieh Behjat Khatooni , Mohsen Soryani

In medical image processing, the most important information is often located on small parts of the image. Patch-based approaches aim at using only the most relevant parts of the image. Finding ways to automatically select the patches is a…

Computer Vision and Pattern Recognition · Computer Science 2022-06-29 Guillaume Lachaud , Patricia Conde-Cespedes , Maria Trocan

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

FDG-PET reveals altered brain metabolism in individuals with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Some biomarkers derived from FDG-PET by computer-aided-diagnosis (CAD) technologies have been proved that they can…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Wenju Cui , Caiying Yan , Zhuangzhi Yan , Yunsong Peng , Yilin Leng , Chenlu Liu , Shuangqing Chen , Xi Jiang

Self-supervised learning methods based on image patch reconstruction have witnessed great success in training auto-encoders, whose pre-trained weights can be transferred to fine-tune other downstream tasks of image understanding. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Junjia Huang , Haofeng Li , Guanbin Li , Xiang Wan

Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Nabil Daiyan , Md Rakibul Haque

Prediction of the cognitive evolution of a person susceptible to develop a neurodegenerative disorder is crucial to provide an appropriate treatment as soon as possible. In this paper we propose a 3D siamese network designed to extract…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Cecilia Ostertag , Marie Beurton-Aimar , Thierry Urruty

One of the main obstacles of adopting digital pathology is the challenge of efficient processing of hyperdimensional digitized biopsy samples, called whole slide images (WSIs). Exploiting deep learning and introducing compact WSI…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Azam Asilian Bidgoli , Shahryar Rahnamayan , Taher Dehkharghanian , Abtin Riasatian , H. R. Tizhoosh

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

Signal Processing · Electrical Eng. & Systems 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi