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Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

Neurons and Cognition · Quantitative Biology 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Deep learning has become the mainstream methodological choice for analyzing and interpreting whole-slide digital pathology images (WSIs). It is commonly assumed that tumor regions carry most predictive information. In this paper, we…

Quantitative Methods · Quantitative Biology 2022-04-26 Zihan Chen , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu

While graph convolution based methods have become the de-facto standard for graph representation learning, their applications to disease prediction tasks remain quite limited, particularly in the classification of neurodevelopmental and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Ibrahim Salim , A. Ben Hamza

Neuroevolution is one of the methodologies that can be used for learning optimal architecture during training. It uses evolutionary algorithms to generate the topology of artificial neural networks and its parameters. The main benefits are…

Neural and Evolutionary Computing · Computer Science 2022-08-30 M. Pietroń , D. Żurek , K. Faber , R. Corizzo

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

Image and Video Processing · Electrical Eng. & Systems 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

Early brain development is crucial for lifelong neurodevelopmental health. However, current clinical practice offers limited knowledge of normal embryonic brain anatomy on ultrasound, despite the brain undergoing rapid changes within the…

Alzheimer's Disease (AD) is a progressive disease preceded by Mild Cognitive Impairment (MCI). Early detection of AD is crucial for making treatment decisions. However, most of the literature on computer-assisted detection of AD focuses on…

Image and Video Processing · Electrical Eng. & Systems 2023-09-15 Misgina Tsighe Hagos , Niamh Belton , Ronan P. Killeen , Kathleen M. Curran , Brian Mac Namee

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders worldwide. As it progresses, it leads to the deterioration of cognitive functions. Since AD is irreversible, early diagnosis is crucial for managing its…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Mahdieh Behjat Khatooni , Mohsen Soryani

Predicting whether subjects with mild cognitive impairment (MCI) will convert to Alzheimer's disease is a significant clinical challenge. Longitudinal variations and complementary information inherent in longitudinal and multimodal data are…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Tao Wang , Xiumei Chen , Xiaoling Zhang , Shuoling Zhou , Qianjin Feng , Meiyan Huang

Mild traumatic brain injury is a growing public health problem with an estimated incidence of over 1.7 million people annually in US. Diagnosis is based on clinical history and symptoms, and accurate, concrete measures of injury are…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Shervin Minaee , Yao Wang , Anna Choromanska , Sohae Chung , Xiuyuan Wang , Els Fieremans , Steven Flanagan , Joseph Rath , Yvonne W Lui

Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Adrian V. Dalca , Evan Yu , Polina Golland , Bruce Fischl , Mert R. Sabuncu , Juan Eugenio Iglesias

Brain age estimation from Magnetic Resonance Images (MRI) derives the difference between a subject's biological brain age and their chronological age. This is a potential biomarker for neurodegeneration, e.g. as part of Alzheimer's disease.…

Computer Vision and Pattern Recognition · Computer Science 2020-10-02 Kyriaki-Margarita Bintsi , Vasileios Baltatzis , Arinbjörn Kolbeinsson , Alexander Hammers , Daniel Rueckert

While existing predictive frameworks are able to handle Euclidean structured data (i.e, brain images), they might fail to generalize to geometric non-Euclidean data such as brain networks. Besides, these are rooted the sample selection step…

Computer Vision and Pattern Recognition · Computer Science 2020-09-24 Ahmet Serkan Goktas , Alaa Bessadok , Islem Rekik

The early detection of Alzheimer's Disease is imperative to ensure early treatment and improve patient outcomes. There has consequently been extenstive research into detecting AD and its intermediate phase, mild cognitive impairment (MCI).…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Jamie Vo , Naeha Sharif , Ghulam Mubashar Hassan

Accurate modeling of cognitive decline in Alzheimer's disease is essential for early stratification and personalized management. While tabular predictors provide robust markers of global risk, their ability to capture subtle brain changes…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Nathaniel Putera , Daniel Vilet Rodríguez , Noah Videcrantz , Julia Machnio , Mostafa Mehdipour Ghazi

For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Hongyoon Choi , Kyong Hwan Jin

Cross-subject motor imagery (CS-MI) classification in brain-computer interfaces (BCIs) is a challenging task due to the significant variability in Electroencephalography (EEG) patterns across different individuals. This variability often…

Machine Learning · Computer Science 2025-07-04 Ahmed G. Habashi , Ahmed M. Azab , Seif Eldawlatly , Gamal M. Aly

The classification of MRI images according to the anatomical field of view is a necessary task to solve when faced with the increasing quantity of medical images. In parallel, advances in deep learning makes it a suitable tool for computer…

Machine Learning · Computer Science 2017-01-17 Hadrien Bertrand , Matthieu Perrot , Roberto Ardon , Isabelle Bloch

Electroencephalography (EEG) classification is a versatile and portable technique for building non-invasive Brain-computer Interfaces (BCI). However, the classifiers that decode cognitive states from EEG brain data perform poorly when…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Anupam Sharma , Krishna Miyapuram

Mild cognitive impairment (MCI) is characterized by subtle changes in cognitive functions, often associated with disruptions in brain connectivity. The present study introduces a novel fine-grained analysis to examine topological…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Ninad Aithal , Debanjali Bhattacharya , Neelam Sinha , Thomas Gregor Issac