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Phylogenetic inference, the task of reconstructing how related sequences evolved from common ancestors, is a central objective in evolutionary genomics. The current state-of-the-art methods exploit probabilistic models of sequence evolution…

Populations and Evolution · Quantitative Biology 2026-02-19 Luc Blassel , Noémie Sauvage , Pierre Barrat-Charlaix , Bastien Boussau , Nicolas Lartillot , Laurent Jacob

We present Causal Posterior Estimation (CPE), a novel method for Bayesian inference in simulator models, i.e., models where the evaluation of the likelihood function is intractable or too computationally expensive, but where one can…

Machine Learning · Computer Science 2025-05-28 Simon Dirmeier , Antonietta Mira

Genetic data are often used to infer demographic history and changes or detect genes under selection. Inferential methods are commonly based on models making various strong assumptions: demography and population structures are supposed…

Populations and Evolution · Quantitative Biology 2020-07-28 Clotilde Lepers , Sylvain Billiard , Matthieu Porte , Sylvie Méléard , Viet Chi Tran

Prediction methods for time-to-event outcomes often utilize survival models that rely on strong assumptions about noninformative censoring or on how individual-level covariates and survival functions are related. When the main interest is…

Methodology · Statistics 2024-02-29 Mahsa Ashouri , Nicholas C. Henderson

A probabilistic program defines a probability measure over its semantic structures. One common goal of probabilistic programming languages (PPLs) is to compute posterior probabilities for arbitrary models and queries, given observed…

Artificial Intelligence · Computer Science 2016-07-01 Yi Wu , Lei Li , Stuart Russell , Rastislav Bodik

Building a good predictive model requires an array of activities such as data imputation, feature transformations, estimator selection, hyper-parameter search and ensemble construction. Given the large, complex and heterogenous space of…

Machine Learning · Computer Science 2019-03-06 Udayan Khurana , Horst Samulowitz

We consider the problem of Bayesian inference in the family of probabilistic models implicitly defined by stochastic generative models of data. In scientific fields ranging from population biology to cosmology, low-level mechanistic…

Since upcoming telescopes will observe thousands of strong lensing systems, creating fully-automated analysis pipelines for these images becomes increasingly important. In this work, we make a step towards that direction by developing the…

Cosmology and Nongalactic Astrophysics · Physics 2020-06-03 Marco Chianese , Adam Coogan , Paul Hofma , Sydney Otten , Christoph Weniger

Survival analysis concerns the task of predicting the time until an event occurs. Often used in the medical field, survival analysis deals with incomplete (i.e., censored) data, for instance, from patients who did not experience the event…

Machine Learning · Computer Science 2026-05-29 Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten

Probabilistic Latent Tensor Factorization (PLTF) is a recently proposed probabilistic framework for modelling multi-way data. Not only the common tensor factorization models but also any arbitrary tensor factorization structure can be…

Computation · Statistics 2014-09-30 Beyza Ermis , Y. Kenan Yılmaz , A. Taylan Cemgil , Evrim Acar

Probabilistic load forecasting (PLF) is a key component in the extended tool-chain required for efficient management of smart energy grids. Neural networks are widely considered to achieve improved prediction performances, supporting highly…

Signal Processing · Electrical Eng. & Systems 2021-01-12 Alessandro Brusaferri , Matteo Matteucci , Stefano Spinelli , Andrea Vitali

Until recently, the use of Bayesian inference in population genetics was limited to a few cases because for many realistic population genetic models the likelihood function cannot be calculated analytically . The situation changed with the…

Methodology · Statistics 2009-01-16 Christoph Leuenberger Daniel Wegmann Laurent Excoffier

Continuous-time birth-death-shift (BDS) processes are frequently used in stochastic modeling, with many applications in ecology and epidemiology. In particular, such processes can model evolutionary dynamics of transposable elements -…

Methodology · Statistics 2014-12-02 Jason Xu , Peter Guttorp , Midori Kato-Maeda , Vladimir N. Minin

In material science, models are derived to predict emergent material properties (e.g. elasticity, strength, conductivity) and their relations to processing conditions. A major drawback is the calibration of model parameters that depend on…

Neural and Evolutionary Computing · Computer Science 2021-11-22 Gabriel Kronberger , Evgeniya Kabliman , Johannes Kronsteiner , Michael Kommenda

In this review, we discuss the applications of the theory of birth-and-death processes to problems in biology, primarily, those of evolutionary genomics. The mathematical principles of the theory of these processes are briefly described.…

Quantitative Methods · Quantitative Biology 2007-05-23 Artem S. Novozhilov , Georgy P. Karev , Eugene V. Koonin

In this study we develop an alternative way to model the ocean reflecting the chaotic nature of ocean flows and uncertainty of ocean models -- instead of making use of classical deterministic or stochastic differential equations we offer a…

Fluid Dynamics · Physics 2023-02-20 Igor Shevchenko , Pavel Berloff

Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-based phylogenetic methods cannot be applied to large volumes of short…

Populations and Evolution · Quantitative Biology 2010-04-01 Frederick A Matsen , Robin B Kodner , E Virginia Armbrust

Standard evolutionary theories of aging and mortality, implicitly based on assumptions of spatial averaging, hold that natural selection cannot favor shorter lifespan without direct compensating benefit to individual reproductive success.…

Populations and Evolution · Quantitative Biology 2015-06-15 Justin Werfel , Donald E. Ingber , Yaneer Bar-Yam

Many real-world classification problems often have classes with very few labeled training samples. Moreover, all possible classes may not be initially available for training, and may be given incrementally. Deep learning models need to deal…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Pratik Mazumder , Pravendra Singh , Piyush Rai

Probabilistic Logic Programming (PLP), exemplified by Sato and Kameya's PRISM, Poole's ICL, Raedt et al's ProbLog and Vennekens et al's LPAD, is aimed at combining statistical and logical knowledge representation and inference. A key…

Artificial Intelligence · Computer Science 2012-10-09 Muhammad Asiful Islam , C. R. Ramakrishnan , I. V. Ramakrishnan