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Probabilistic programming languages (PPLs) are a powerful modeling tool, able to represent any computable probability distribution. Unfortunately, probabilistic program inference is often intractable, and existing PPLs mostly rely on…

Artificial Intelligence · Computer Science 2016-10-19 Daniel Ritchie , Paul Horsfall , Noah D. Goodman

Probabilistic programming frameworks are powerful tools for statistical modelling and inference. They are not immediately generalisable to phylogenetic problems due to the particular computational properties of the phylogenetic tree object.…

Populations and Evolution · Quantitative Biology 2022-11-11 Christiaan Swanepoel , Mathieu Fourment , Xiang Ji , Hassan Nasif , Marc A Suchard , Frederick A Matsen , Alexei Drummond

This book is a graduate-level introduction to probabilistic programming. It not only provides a thorough background for anyone wishing to use a probabilistic programming system, but also introduces the techniques needed to design and build…

Machine Learning · Statistics 2021-10-20 Jan-Willem van de Meent , Brooks Paige , Hongseok Yang , Frank Wood

Particle filtering methods can be applied to estimation problems in discrete spaces on bounded domains, to sample from and marginalise over unknown hidden states. As in continuous settings, problems such as particle degradation can arise:…

Gene gain-loss-duplication models are commonly based on continuous-time birth-death processes. Employed in a phylogenetic context, such models have been increasingly popular in studies of gene content evolution across multiple genomes.…

Populations and Evolution · Quantitative Biology 2021-07-27 Miklos Csuros

Universal probabilistic programming languages (PPLs) make it relatively easy to encode and automatically solve statistical inference problems. To solve inference problems, PPL implementations often apply Monte Carlo inference algorithms…

Programming Languages · Computer Science 2024-04-08 Daniel Lundén , Lars Hummelgren , Jan Kudlicka , Oscar Eriksson , David Broman

Many of today's probabilistic programming languages (PPLs) have brittle inference performance: the performance of the underlying inference algorithm is very sensitive to the precise way in which the probabilistic program is written. A…

Artificial Intelligence · Computer Science 2023-02-22 Ellie Y. Cheng , Todd Millstein , Guy Van den Broeck , Steven Holtzen

Birth-death processes (BDPs) are continuous-time Markov chains that track the number of "particles" in a system over time. While widely used in population biology, genetics and ecology, statistical inference of the instantaneous particle…

Methodology · Statistics 2011-11-22 Forrest W. Crawford , Vladimir N. Minin , Marc A. Suchard

A phylogenetic birth-and-death model is a probabilistic graphical model for a so-called phylogenetic profile, i.e., the size distribution for a homolog gene family at the terminal nodes of a phylogeny. Profile datasets are used in…

Populations and Evolution · Quantitative Biology 2009-02-06 Miklós Csűrös , István Miklós

Compared to the wide array of advanced Monte Carlo methods supported by modern probabilistic programming languages (PPLs), PPL support for variational inference (VI) is less developed: users are typically limited to a predefined selection…

Programming Languages · Computer Science 2024-06-25 McCoy R. Becker , Alexander K. Lew , Xiaoyan Wang , Matin Ghavami , Mathieu Huot , Martin C. Rinard , Vikash K. Mansinghka

Based on probability density evolution method (PDEM) and Bayes law, a new filter strategy is proposed, in which the prior probability of system state of interest is predicted by solving the general density evolution equation (GDEE), the…

Signal Processing · Electrical Eng. & Systems 2021-07-21 Yazhou Xu

Auxiliary particle filters (APFs) are a class of sequential Monte Carlo (SMC) methods for Bayesian inference in state-space models. In their original derivation, APFs operate in an extended state space using an auxiliary variable to improve…

Computation · Statistics 2021-06-17 Nicola Branchini , Víctor Elvira

Many important stochastic counting models can be written as general birth-death processes (BDPs). BDPs are continuous-time Markov chains on the non-negative integers and can be used to easily parameterize a rich variety of probability…

Methodology · Statistics 2014-07-28 Forrest W. Crawford , Marc A. Suchard

Probabilistic programming languages (PPLs) are expressive means for creating and reasoning about probabilistic models. Unfortunately hybrid probabilistic programs, involving both continuous and discrete structures, are not well supported by…

Programming Languages · Computer Science 2024-06-25 Poorva Garg , Steven Holtzen , Guy Van den Broeck , Todd Millstein

In order to numerically solve high-dimensional nonlinear PDEs and alleviate the curse of dimensionality, a stochastic particle method (SPM) has been proposed to capture the relevant feature of the solution through the adaptive evolution of…

Numerical Analysis · Mathematics 2026-03-16 Jingyang Huang , Zhengyang Lei , Sihong Shao

Despite the recent successes of probabilistic programming languages (PPLs) in AI applications, PPLs offer only limited support for random variables whose distributions combine discrete and continuous elements. We develop the notion of…

Artificial Intelligence · Computer Science 2018-06-11 Yi Wu , Siddharth Srivastava , Nicholas Hay , Simon Du , Stuart Russell

We propose Diffusion Model Variational Inference (DMVI), a novel method for automated approximate inference in probabilistic programming languages (PPLs). DMVI utilizes diffusion models as variational approximations to the true posterior…

Machine Learning · Computer Science 2023-11-23 Simon Dirmeier , Fernando Perez-Cruz

This paper is concerned with particle filtering for $\alpha$-stable stochastic volatility models. The $\alpha$-stable distribution provides a flexible framework for modeling asymmetry and heavy tails, which is useful when modeling financial…

Computation · Statistics 2014-05-20 Emilian Vankov , Katherine B. Ensor

By providing a framework of accounting for the shared ancestry inherent to all life, phylogenetics is becoming the statistical foundation of biology. The importance of model choice continues to grow as phylogenetic models continue to…

Populations and Evolution · Quantitative Biology 2019-02-05 Jamie R. Oaks , Kerry A. Cobb , Vladimir N. Minin , Adam D. Leaché

Probabilistic Programming Languages (PPLs) are a powerful tool in machine learning, allowing highly expressive generative models to be expressed succinctly. They couple complex inference algorithms, implemented by the language, with an…

Programming Languages · Computer Science 2020-10-19 Alexander Collins , Vinod Grover
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