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Related papers: Quantifying Confounding Bias in Neuroimaging Datas…

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Although deep learning techniques show promising results for many neuroimaging tasks in research settings, they have not yet found widespread use in clinical scenarios. One of the reasons for this problem is that many machine learning…

Image and Video Processing · Electrical Eng. & Systems 2024-12-05 Vibujithan Vigneshwaran , Erik Ohara , Matthias Wilms , Nils Forkert

This is an empirical study to investigate the impact of scanner effects when using machine learning on multi-site neuroimaging data. We utilize structural T1-weighted brain MRI obtained from two different studies, Cam-CAN and UK Biobank.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Ben Glocker , Robert Robinson , Daniel C. Castro , Qi Dou , Ender Konukoglu

A common approach in neuroscience is to study neural representations as a means to understand a system -- increasingly, by relating the neural representations to the internal representations learned by computational models. However, a…

Neurons and Cognition · Quantitative Biology 2025-08-14 Andrew Kyle Lampinen , Stephanie C. Y. Chan , Yuxuan Li , Katherine Hermann

Cognitive brain imaging is accumulating datasets about the neural substrate of many different mental processes. Yet, most studies are based on few subjects and have low statistical power. Analyzing data across studies could bring more…

Machine Learning · Statistics 2021-05-20 Arthur Mensch , Julien Mairal , Bertrand Thirion , Gaël Varoquaux

Pruning - that is, setting a significant subset of the parameters of a neural network to zero - is one of the most popular methods of model compression. Yet, several recent works have raised the issue that pruning may induce or exacerbate…

Computer Vision and Pattern Recognition · Computer Science 2023-04-26 Eugenia Iofinova , Alexandra Peste , Dan Alistarh

To unbiasedly estimate a causal effect on an outcome unconfoundedness is often assumed. If there is sufficient knowledge on the underlying causal structure then existing confounder selection criteria can be used to select subsets of the…

Methodology · Statistics 2017-03-20 Jenny Häggström

Medical multimodal representation learning aims to integrate heterogeneous clinical data into unified patient representations to support predictive modeling, which remains an essential yet challenging task in the medical data mining…

Machine Learning · Computer Science 2025-09-09 Xiaoguang Zhu , Lianlong Sun , Yang Liu , Pengyi Jiang , Uma Srivatsa , Nipavan Chiamvimonvat , Vladimir Filkov

Cognitive neuroscience is enjoying rapid increase in extensive public brain-imaging datasets. It opens the door to large-scale statistical models. Finding a unified perspective for all available data calls for scalable and automated…

Machine Learning · Statistics 2019-05-16 Arthur Mensch , Julien Mairal , Danilo Bzdok , Bertrand Thirion , Gaël Varoquaux

The lack of non-parametric statistical tests for confounding bias significantly hampers the development of robust, valid and generalizable predictive models in many fields of research. Here I propose the partial and full confounder tests,…

Machine Learning · Computer Science 2025-05-30 Tamas Spisak

In computer vision, a prevailing method for quantifying dataset bias is to train a model to distinguish between datasets. High classification accuracy is then interpreted as evidence of meaningful semantic differences. This approach assumes…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Amir Hossein Saleknia , Mohammad Sabokrou

While causal models are becoming one of the mainstays of machine learning, the problem of uncertainty quantification in causal inference remains challenging. In this paper, we study the causal data fusion problem, where datasets pertaining…

Machine Learning · Statistics 2021-06-08 Siu Lun Chau , Jean-François Ton , Javier González , Yee Whye Teh , Dino Sejdinovic

Unmeasured confounding presents a common challenge in observational studies, potentially making standard causal parameters unidentifiable without additional assumptions. Given the increasing availability of diverse data sources, exploiting…

Methodology · Statistics 2023-09-18 Shanshan Luo , Yechi Zhang , Wei Li

This article discusses how the language of causality can shed new light on the major challenges in machine learning for medical imaging: 1) data scarcity, which is the limited availability of high-quality annotations, and 2) data mismatch,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Daniel C. Castro , Ian Walker , Ben Glocker

Medical machine learning algorithms are typically evaluated based on accuracy vs. a clinician-defined ground truth, a reasonable initial choice since trained clinicians are usually better classifiers than ML models. However, this metric…

Machine Learning · Computer Science 2024-05-21 Charles B. Delahunt , Courosh Mehanian , Matthew P. Horning

The emergence of large-scale pre-trained vision foundation models has greatly advanced the medical imaging field through the pre-training and fine-tuning paradigm. However, selecting appropriate medical data for downstream fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Anyang Ji , Qingbo Kang , Wei Xu , Changfan Wang , Kang Li , Qicheng Lao

Learning-based signal processing systems increasingly support high-stakes medical decisions using heterogeneous biomedical signals, including medical images, physiological time series, and clinical records. Despite strong predictive…

Signal Processing · Electrical Eng. & Systems 2026-03-02 Surajit Das , Maxine Tan

Bayesian causal inference offers a principled approach to policy evaluation of proposed interventions on mediators or time-varying exposures. We outline a general approach to the estimation of causal quantities for settings with…

Methodology · Statistics 2019-02-28 Leah Comment , Brent A. Coull , Corwin Zigler , Linda Valeri

Unlike parametric regression, machine learning (ML) methods do not generally require precise knowledge of the true data generating mechanisms. As such, numerous authors have advocated for ML methods to estimate causal effects.…

Methodology · Statistics 2020-05-15 Ashley I Naimi , Alan E Mishler , Edward H Kennedy

Although deep learning prediction models have been successful in the discrimination of different classes, they can often suffer from poor calibration across challenging domains including healthcare. Moreover, the long-tail distribution…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Riqiang Gao , Thomas Li , Yucheng Tang , Zhoubing Xu , Michael Kammer , Sanja L. Antic , Kim Sandler , Fabien Moldonado , Thomas A. Lasko , Bennett Landman

In whole slide images (WSIs) analysis, attention-based multi-instance learning (MIL) models are susceptible to spurious correlations and degrade under domain shift. These methods may assign high attention weights to non-tumor regions, such…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Xin Liu , Weijia Zhang , Wei Tang , Thuc Duy Le , Jiuyong Li , Lin Liu , Min-Ling Zhang