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This paper presents an intracellular feedback control strategy, to regulate the gene expression process dynamics. For this purpose, two types of genetic circuits are designed in order to compare concentrations of the input transcription…

Systems and Control · Computer Science 2016-06-15 Jafar Kazemi , Sadjad Ozgoli

Differential equations are a ubiquitous tool to study dynamics, ranging from physical systems to complex systems, where a large number of agents interact through a graph with non-trivial topological features. Data-driven approximations of…

Statistical Mechanics · Physics 2024-04-26 Vaiva Vasiliauskaite , Nino Antulov-Fantulin

We present a method for using neural networks to model evolutionary population dynamics, and draw parallels to recent deep learning advancements in which adversarially-trained neural networks engage in coevolutionary interactions. We…

Neural and Evolutionary Computing · Computer Science 2018-04-13 Nick Moran , Jordan Pollack

With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…

Genomics · Quantitative Biology 2022-04-14 Attayeb Mohsen , Lokesh P. Tripathi , Kenji Mizuguchi

Interpersonal relation defines the association, e.g., warm, friendliness, and dominance, between two or more people. Motivated by psychological studies, we investigate if such fine-grained and high-level relation traits can be characterized…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Zhanpeng Zhang , Ping Luo , Chen Change Loy , Xiaoou Tang

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

Machine Learning · Computer Science 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

We present a technique to characterize differentially expressed genes in terms of their position in a high-dimensional co-expression network. The set-up of Gaussian graphical models is used to construct representations of the co-expression…

Applications · Statistics 2010-11-17 Gabriel C. G. de Abreu , Rodrigo Labouriau

Relatively small data sets available for expression recognition research make the training of deep networks for expression recognition very challenging. Although fine-tuning can partially alleviate the issue, the performance is still below…

Computer Vision and Pattern Recognition · Computer Science 2016-09-23 Hui Ding , Shaohua Kevin Zhou , Rama Chellappa

Knowledge of patients affective state could prove to be crucial for health-care professionals in both diagnosis and treatment, however, this requires patients to report how they feel. In practice the sampling rate of affective states needs…

Computers and Society · Computer Science 2017-05-12 Stina Lyck Carstensen , Jens Madsen , Jan Larsen

Neural network-based Open-ended conversational agents automatically generate responses based on predictive models learned from a large number of pairs of utterances. The generated responses are typically acceptable as a sentence but are…

Computation and Language · Computer Science 2019-05-16 Chenyang Huang , Osmar R. Zaïane

A novel procedure is presented in this paper, for training a deep convolutional and recurrent neural network, taking into account both the available training data set and some information extracted from similar networks trained with other…

Machine Learning · Computer Science 2018-09-13 Dimitrios Kollias , Stefanos Zafeiriou

It is tempting to think that machines are less prone to unfairness and prejudice. However, machine learning approaches compute their outputs based on data. While biases can enter at any stage of the development pipeline, models are…

Computer Vision and Pattern Recognition · Computer Science 2020-12-07 Patrick Esser , Robin Rombach , Björn Ommer

Graph Neural Networks (GNNs) are powerful tools for learning on structured data, yet the relationship between their expressivity and predictive performance remains unclear. We introduce a family of premetrics that capture different degrees…

Machine Learning · Computer Science 2025-05-19 Sohir Maskey , Raffaele Paolino , Fabian Jogl , Gitta Kutyniok , Johannes F. Lutzeyer

Biological systems are driven by intricate interactions among the complex array of molecules that comprise the cell. Many methods have been developed to reconstruct network models of those interactions. These methods often draw on large…

Molecular Networks · Quantitative Biology 2018-06-29 Marieke Lydia Kuijjer , Matthew Tung , GuoCheng Yuan , John Quackenbush , Kimberly Glass

Referring Expression Generation (REG) is the task of generating contextually appropriate references to entities. A limitation of existing REG systems is that they rely on entity-specific supervised training, which means that they cannot…

Computation and Language · Computer Science 2019-09-05 Meng Cao , Jackie Chi Kit Cheung

This study evaluates the efficacy of two machine learning (ML) techniques, namely artificial neural networks (ANN) and gene expression programming (GEP) that use data-driven modeling to predict wall pressure spectra (WPS) underneath…

Fluid Dynamics · Physics 2024-02-27 Nachiketa Narayan Kurhade , Nagabhushana Rao Vadlamani , Akash Haridas

Neural networks have recently achieved human-level performance on various challenging natural language processing (NLP) tasks, but it is notoriously difficult to understand why a neural network produced a particular prediction. In this…

Computation and Language · Computer Science 2020-05-01 Sharan Narang , Colin Raffel , Katherine Lee , Adam Roberts , Noah Fiedel , Karishma Malkan

The genetic etiologies of common diseases are highly complex and heterogeneous. Classic statistical methods, such as linear regression, have successfully identified numerous genetic variants associated with complex diseases. Nonetheless,…

Applications · Statistics 2020-10-28 Jinghang Lin , Xiaoran Tong , Chenxi Li , Qing Lu

We introduce twin neural network (TNN) regression. This method predicts differences between the target values of two different data points rather than the targets themselves. The solution of a traditional regression problem is then obtained…

Machine Learning · Computer Science 2022-12-14 Sebastian J. Wetzel , Kevin Ryczko , Roger G. Melko , Isaac Tamblyn

While a lot of analysis has been carried to demonstrate linguistic knowledge captured by the representations learned within deep NLP models, very little attention has been paid towards individual neurons.We carry outa neuron-level analysis…

Computation and Language · Computer Science 2020-10-07 Nadir Durrani , Hassan Sajjad , Fahim Dalvi , Yonatan Belinkov
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