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Anisotropic nanomaterials possess interesting thermal transport properties because they allow orientation of heat fluxes along preferential directions due to a high ratio (up to three orders of magnitude) between their in-plane and…

Materials Science · Physics 2017-01-10 Mykola Isaiev , Oles Didukh , Tetyana Nychyporuk , Victor Timoshenko , Vladimir Lysenko

We present a mathematical model that describes how tumour heterogeneity evolves in a tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the stemness level of a cell, $s$, that determines its proliferative…

Cell Behavior · Quantitative Biology 2023-11-14 Giulia L. Celora , Helen M. Byrne , P. G. Kevrekidis

In this work, we study quantum heat transport in a single trapped ion, driven by laser excitation and coupled to thermal reservoirs operating at different temperatures. Our focus lies in understanding how different laser coupling scenarios…

Quantum Physics · Physics 2025-03-03 T. Tassis , F. Brito , F. L. Semião

Heat conduction in one-dimensional (1D) systems is studied based on an analytical S-matrix method, which is developed in the mesoscopic electronic transport theory and molecular dynamic (MD) simulations. It is found that heat conduction in…

Statistical Mechanics · Physics 2007-05-23 Xin Zhou , Mitsumasa Iwamoto

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

We study the dynamics and interactions between combined chemotherapy and chimeric antigen receptor (CAR-T) cells therapy and malignant gliomas (MG). MG is one of the most common primary brain tumor, with high resistance to therapy and…

Dynamical Systems · Mathematics 2025-06-04 Dmitry Sinelshchikov , Juan Belmonte-Beitia , Matteo Italia

We solved the radiative transfer and statistical equilibrium equations in a two-dimensional cross-section of a cylindrical structure oriented horizontally and lying above the solar surface. The cylinder is filled with a mixture of hydrogen…

Solar and Stellar Astrophysics · Physics 2016-03-02 N. Labrosse , A. S. Rodger

We derive a full 3-dimensional (3-D) model of inhomogeneous -- anisotropic diffusion in a tumor region coupled to a binary population model. The diffusion tensors are acquired using Diffusion Tensor Magnetic Resonance Imaging (DTI) from a…

Medical Physics · Physics 2021-01-04 Erdi Kara , Aminur Rahman , Eugenio Aulisa , Souparno Ghosh

We develop a new four-phase tumor growth model with angiogenesis, derived from a diffuse-interface mixture model composed by a viable, a necrotic, a liquid and an angiogenetic component, coupled with two massless chemicals representing a…

Numerical Analysis · Mathematics 2022-03-07 Abramo Agosti , Alice Giotta Lucifero , Sabino Luzzi

A systematic understanding of the evolution and growth dynamics of invasive solid tumors in response to different chemotherapy strategies is crucial for the development of individually optimized oncotherapy. Here, we develop a hybrid…

Tissues and Organs · Quantitative Biology 2020-07-01 Hang Xie , Yang Jiao , Qihui Fan , Miaomiao Hai , Jiaen Yang , Zhijian Hu , Yue Yang , Jianwei Shuai , Guo Chen , Ruchuan Liu , Liyu Liu

Theoretical framework for the isosteric heat of adsorption is developed treating the effects of the non-ideal gas behavior and the adsorbed phase volume. Rigorous thermodynamic treatment for the adsorbed phase volume is presented for…

Chemical Physics · Physics 2017-09-07 Kyaw Thu , Sourav Mitra , Bidyut Baran Saha

We consider a particular phase field system which physical context is that of tumor growth dynamics. The model we deal with consists of a Cahn-Hilliard type equation governing the evolution of the phase variable which takes into account the…

Analysis of PDEs · Mathematics 2019-08-30 Andrea Signori

Cytotoxic chemotherapy is a common treatment for advanced prostate cancer. These tumors are also known to rely on angiogenesis, i.e., the growth of local microvasculature via chemical signaling produced by the tumor. Thus, several clinical…

Radiation therapy is an effective and widely accepted form of treatment for many types of cancer that requires extensive computerized planning. Unfortunately, current treatment planning systems have limited or no visual aid that combines…

Graphics · Computer Science 2018-11-30 Felix G. Hamza-Lup , Ivan Sopin , Omar Zeidan

We investigate a method of selectively targeting cancer cells by means of ultrasound harmonic excitation at their resonance frequency, which we refer to as oncotripsy. The geometric model of the cells takes into account the cytoplasm,…

Biological Physics · Physics 2020-07-21 Stefanie Heyden , Michael Ortiz

We apply the picket fence treatment to model the effects brought about by spectral lines on the thermal structure of irradiated atmospheres. The lines may be due to purely absorption processes, purely coherent scattering processes or some…

Earth and Planetary Astrophysics · Physics 2018-05-02 Gopakumar Mohandas , Martin E. Pessah , Kevin Heng

In this paper, we studied phase-space analysis of a certain mathematical model of tumor growth with an immune responses and chemotherapy therapy. Mathematical modelling of this process is viewed as a potentially powerful tool in the…

Dynamical Systems · Mathematics 2018-03-15 Veli Shakhmurov , Akif Maharramov , Bunyad Shahmurzada

Calculations of time-resolved fluorescence anisotropy from a pair of chromophores coupled by an excitation transfer interaction are presented. For the purpose of investigating the effects of nuclear motion on the energy transfer and…

chem-ph · Physics 2008-02-03 Alexander Matro , Jeffrey A. Cina

Chimeric antigen receptor (CAR) T cell therapy is revolutionizing the treatment of blood cancers. Mathematical models that can predict the effectiveness of immunotherapies such as CAR T are of increasing interest due to their ability to…

Systems and Control · Electrical Eng. & Systems 2024-11-13 Raffaele Romagnoli

In this work, we focus on the analytical and numerical study of a mathematical model for brain tumors with radiotherapy influence. Under certain assumptions on the given data in the model, we prove existence and uniqueness of a weak…

Analysis of PDEs · Mathematics 2024-09-27 Marina Chugunova , Hangjie Ji , Roman Taranets , Nataliya Vasylyeva