English
Related papers

Related papers: Spontaneous Domain Formation in Spherically-Confin…

200 papers

In this paper we study the role of topology in DNA gel electrophoresis experiments via molecular dynamics simulations. The gel is modelled as a 3D array of obstacles from which half edges are removed at random with probability p, thereby…

Soft Condensed Matter · Physics 2015-04-10 Davide Michieletto , Marco Baiesi , Enzo Orlandini , Matthew S. Turner

We characterize the self-assembly of colloidal particles with surface mobile DNA linkers under kinetically limited valence conditions. For this, we put forward a computer simulation model that captures quantitatively the interplay between…

Soft Condensed Matter · Physics 2022-10-26 Pedro A. Sánchez , Alessio Caciagli , Sofia S. Kantorovich , Erika Eiser

We determine the phase diagram of DNA with inter- and intra-strand native-pair interactions that mimic the compaction of DNA. We show that DNA takes an overall sheet-like structure in the region where an incipient transition to a compact…

Soft Condensed Matter · Physics 2024-04-15 Garima Mishra , Somendra M. Bhattacharjee

Understanding how virus capsids assemble around their nucleic acid (NA) genomes could promote efforts to block viral propagation or to reengineer capsids for gene therapy applications. We develop a coarse-grained model of capsid proteins…

Biomolecules · Quantitative Biology 2014-05-15 Jason D. Perlmutter , Cong Qiao , Michael F. Hagan

We study the coarsening of strongly microphase separated membrane domains in the presence of recycling of material. We study the dynamics of the domain size distribution under both scale-free and size-dependent recycling. Closed form…

Subcellular Processes · Quantitative Biology 2018-05-11 S. Alex Rautu , G. Rowlands , M. S. Turner

Soft-granular media, such as dense emulsions, foams or tissues, exhibit either fluid- or solid-like properties depending on the applied external stresses. Whereas bulk rheology of such materials has been thoroughly investigated, the…

Soft Condensed Matter · Physics 2024-07-04 Michal Bogdan , Jesus Pineda , Mihir Durve , Leon Jurkiewicz , Sauro Succi , Giovanni Volpe , Jan Guzowski

The dynamics of a domain wall driven by a spin-polarized current in a mesoscopic system is studied numerically. Spin-mixing in the states of the conduction electrons is fully taken into account. When the Fermi energy of the electrons is…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 Jun-ichiro Ohe , Bernhard Kramer

Confinement can significantly alter fluid properties, offering potential for specific technological applications. However, achieving precise control over the structural complexity of confined fluids and soft matter remains challenging, as…

Soft Condensed Matter · Physics 2024-11-20 Fabio Leoni , Erdal C. Oğuz , Giancarlo Franzese

DNA in sperm cells must undergo an extreme compaction to almost crystalline packing levels. To produce this dense packing, DNA is condensed by protamine, a positively charged protein that loops the DNA into a toroid. Our goal is to…

In recent years there have been a number of proposals to utilize the specificity of DNA based interactions for potential applications in nanoscience. One interesting direction is the self-assembly of micro- and nanoparticle clusters using…

Soft Condensed Matter · Physics 2009-11-13 Nicholas A. Licata , Alexei V. Tkachenko

The high linear charge density of 20-base-pair oligomers of DNA is shown to lead to a striking non-monotonic dependence of the long-time self-diffusion on the concentration of the DNA in low-salt conditions. This generic non-monotonic…

Soft Condensed Matter · Physics 2009-11-13 M. G. McPhie , G. Naegele

We report a new mechanism of pattern formation in growing bistable systems coupled indirectly. A modified Fujita et. al. model is studied as an example of a reaction-diffusion system of nondiffusive activator and inhibitor molecules…

Pattern Formation and Solitons · Physics 2015-06-23 Dorjsuren Battogtokh

We study sequence dependent complexation between oligonucleotides (single strand DNA) and various generation ethylene diamine (EDA) cored poly amido amide (PAMAM) dendrimers through atomistic molecular dynamics simulations accompanied by…

Soft Condensed Matter · Physics 2015-06-25 Prabal K. Maiti , Biman Bagchi

Structure of monolayers built during adsorption process is strongly related to the properties of adsorbed particles. The most important factor is their shape. For example, adsorption of elongated molecules on patterned surfaces may produce…

Materials Science · Physics 2013-06-28 Jakub Barbasz , Michał Cieśla

Single-stranded (ss) RNA viruses self-assemble spontaneously in solutions that contain the viral RNA genome molecules and the viral capsid proteins. The self-assembly of empty capsids can be understood on the basis of free energy…

Biological Physics · Physics 2021-08-21 Inbal Mizrahi , Robijn Bruinsma , Joseph Rudnick

Single-stranded RNA viruses efficiently encapsulate their genome into a protein shell called the capsid. Electrostatic interactions between the positive charges in the capsid protein's N-terminal tail and the negatively charged genome have…

Biological Physics · Physics 2021-02-03 Yinan Dong , Siyu Li , Roya Zandi

In-vivo DNA organization at large length scales ($\sim 100nm$) is highly debated and polymer models have proved useful to understand the principle of DNA-organization. Here, we show that $<2$% cross-links at specific points in a ring…

Soft Condensed Matter · Physics 2018-04-04 Tejal Agarwal , G. P. Manjunath , Farhat Habib , Apratim Chatterji

The elasticity of DNA catenanes, i.e. multiply linked DNA rings, is investigated using the Gauss invariant as a minimal model for topology conservation. An effective elastic free energy as a function of the distance $R$ between segments…

Soft Condensed Matter · Physics 2007-05-23 M. Otto , T. A. Vilgis

The eukaryotic cell nucleus harbors the DNA genome that is organized in a dynamic chromatin network and embedded in a viscous crowded fluid. This environment directly affects enzymatic reactions and target search processes that access the…

Cell Behavior · Quantitative Biology 2015-06-23 Fabian Erdel , Michael Baum , Karsten Rippe

The mechanism and driving forces of chromosome segregation in the bacterial cell cycle of E. coli is one of the least understood events in its life cycle. Using principles of entropic repulsion between polymer loops confined in a cylinder,…

Soft Condensed Matter · Physics 2021-12-24 Debarshi Mitra , Shreerang Pande , Apratim Chatterji