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We extend the weighted ensemble (WE) path sampling method to perform rigorous statistical sampling for systems at steady state. The straightforward steady-state implementation of WE is directly practical for simple landscapes, but not when…

Biological Physics · Physics 2015-05-14 Divesh Bhatt , Bin W. Zhang , Daniel M. Zuckerman

Knowledge Graph Question Answering (KGQA) aims to answer user questions by reasoning over Knowledge Graphs (KGs). Recent KGQA methods mainly follow the retrieval-augmented generation paradigm to ground Large Language Models~(LLMs) with…

Artificial Intelligence · Computer Science 2026-05-12 Shengxiang Gao , Chao Lei , Jey Han Lau , Jianzhong Qi

Characterizing conformational transitions in physical systems remains a fundamental challenge, as traditional sampling methods struggle with the high-dimensional nature of molecular systems and high-energy barriers between stable states.…

Chemical Physics · Physics 2025-09-22 Magnus Petersen , Gemma Roig , Roberto Covino

Transition-state searches are central to understanding reaction mechanisms, but the high computational cost of density-functional theory (DFT) limits their application in high-throughput catalyst and materials discovery. Machine-learned…

Chemical Physics · Physics 2026-04-02 Jonah Marks , Jonathon Vandezande , Joseph Gomes

Graph Convolutional Networks (GCNs) achieve great success in non-Euclidean structure data processing recently. In existing studies, deeper layers are used in CCNs to extract deeper features of Euclidean structure data. However, for…

Machine Learning · Computer Science 2022-03-14 Junhua Ma , Jiajun Li , Xueming Li , Xu Li

The three-dimensional, three-state Potts model is studied as a paradigm for high temperature quantum chromodynamics. In a high statistics numerical simulation using a Swendson-Wang algorithm, we study cubic lattices of dimension as large as…

High Energy Physics - Lattice · Physics 2008-11-26 Jing-Dong Wang , Carleton DeTar

Understanding disease progression at the molecular pathway level usually requires capturing both structural dependencies between pathways and the temporal dynamics of disease evolution. In this work, we solve the former challenge by…

Machine Learning · Computer Science 2025-02-11 Dai Shi , Kuan Yan , Lequan Lin , Yue Zeng , Ting Zhang , Dmytro Matsypura , Mark C. Gillies , Ling Zhu , Junbin Gao

We give a rigorous proof of two phase transitions for a disordered system designed to find large cliques inside Erdos random graphs. Such a system is associated with a conservative probabilistic cellular automaton inspired by the cavity…

We present three algorithms for calculating rate constants and sampling transition paths for rare events in simulations with stochastic dynamics. The methods do not require a priori knowledge of the phase space density and are suitable for…

Soft Condensed Matter · Physics 2009-11-11 Rosalind J. Allen , Daan Frenkel , Pieter Rein ten Wolde

Popular methods for identifying transition paths between energy minima, such as the nudged elastic band and string methods, typically do not incorporate potential energy curvature information, leading to slow relaxation to the minimum…

Computational Physics · Physics 2019-03-11 Stela Makri , Christoph Ortner , James R. Kermode

Sampling-based motion planning techniques have emerged as an efficient algorithmic paradigm for solving complex motion planning problems. These approaches use a set of probing samples to construct an implicit graph representation of the…

Robotics · Computer Science 2019-10-10 Brian Ichter , Edward Schmerling , Tsang-Wei Edward Lee , Aleksandra Faust

State estimation for hybrid systems that undergo intermittent contact with their environments, such as extraplanetary robots and satellites undergoing docking operations, is difficult due to the discrete uncertainty propagation during…

Robotics · Computer Science 2026-03-23 Karthik Shaji , Sreeranj Jayadevan , Bo Yuan , Hongzhe Yu , Yongxin Chen

A central goal of protein-folding theory is to predict the stochastic dynamics of transition paths --- the rare trajectories that transit between the folded and unfolded ensembles --- using only thermodynamic information, such as a…

Biomolecules · Quantitative Biology 2018-08-09 William M. Jacobs , Eugene I. Shakhnovich

This research paper addresses the challenges of exploration and navigation in unknown environments from an evolutionary swarm robotics perspective. Path formation plays a crucial role in enabling cooperative swarm robots to accomplish these…

Robotics · Computer Science 2023-12-29 Lavanya Ratnabala , Robinroy Peter , E. Y. A. Charles

We have developed a software package CALYPSO (Crystal structure AnaLYsis by Particle Swarm Optimization) to predict the energetically stable/metastable crystal structures of materials at given chemical compositions and external conditions…

Materials Science · Physics 2015-06-05 Yanchao Wang , Jian Lv , Li Zhu , Yanming Ma

An analysis of the network defined by the potential energy minima of multi-atomic systems and their connectivity via reaction pathways that go through transition states allows to understand important characteristics like thermodynamic,…

Materials Science · Physics 2016-08-03 Bastian Schaefer , Stefan Goedecker

We analyze the efficiency of different methods for the calculation of reaction rates in the case of two simple analytical benchmark systems. Two classes of methods are considered: the first are based on the free energy calculation along a…

Statistical Mechanics · Physics 2009-11-11 Titus S. van Erp

We found that Bidirectional LSTM and Transformer can classify different phases of condensed matter models and determine the phase transition points by learning features in the Monte Carlo raw data before equilibrium. Our method can…

Strongly Correlated Electrons · Physics 2022-09-15 Jiewei Ding , Ho-Kin Tang , Wing Chi Yu

Unified graph representation learning aims to generate node embeddings, which can be applied to multiple downstream applications of graph analytics. However, existing studies based on graph neural networks and language models either suffer…

Computation and Language · Computer Science 2025-08-05 Wenbo Shang , Xuliang Zhu , Xin Huang

Stochastic modeling and simulation provide powerful predictive methods for the intrinsic understanding of fundamental mechanisms in complex biochemical networks. Typically, such mathematical models involve networks of coupled jump…

Information Theory · Computer Science 2013-08-02 Yannis Pantazis , Markos A. Katsoulakis , Dionisios G. Vlachos
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