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In this work, we introduce a novel algorithm for the Biot problem based on a Hybrid High-Order discretization of the mechanics and a Symmetric Weighted Interior Penalty discretization of the flow. The method has several assets, including,…

Numerical Analysis · Mathematics 2016-02-25 Daniele Boffi , Michele Botti , Daniele A. Di Pietro

Deformable elastic bodies in viscous and viscoelastic media constitute a large portion of synthetic and biological complex fluids. We present a parallelized 3D-simulation methodology which fully resolves the momentum balance in the solid…

Computational Physics · Physics 2019-03-11 Amir Saadat , Chris J. Guido , Gianluca Iaccarino , Eric S. G. Shaqfeh

The fixed-stress splitting scheme is a popular method for iteratively solving the Biot equations. The method successively solves the flow and mechanic subproblems while adding a stabilizing term to the flow equation, which includes a…

Numerical Analysis · Mathematics 2021-05-24 Erlend Storvik , Jakub Wiktor Both , Jan Martin Nordbotten , Florin Adrian Radu

To accurately reproduce measurements from the real world, simulators need to have an adequate model of the physical system and require the parameters of the model be identified. We address the latter problem of estimating parameters through…

Robotics · Computer Science 2022-03-01 Eric Heiden , Christopher E. Denniston , David Millard , Fabio Ramos , Gaurav S. Sukhatme

The parameters in the governing system of partial differential equations of multicompartmental poroelastic models typically vary over several orders of magnitude making its stable discretization and efficient solution a challenging task. In…

Numerical Analysis · Mathematics 2018-06-12 Qinggou Hong , Johannes Kraus , Maria Lymbery , Fadi Philo

Computational neuroscience relies on large-scale dynamical-systems models of neurons, with a vast amount of offline, pre-simulation, tuned parameters, with models often tied to their brain simulators. These fixed parameters lead to stiff…

Neurons and Cognition · Quantitative Biology 2025-12-25 Lennart P. L. Landsmeer , Mario Negrello , Said Hamdioui , Christos Strydis

For many of the physical phenomena around us, we have developed sophisticated models explaining their behavior. Nevertheless, inferring specifics from visual observations is challenging due to the high number of causally underlying physical…

Computer Vision and Pattern Recognition · Computer Science 2019-10-18 Tom F. H. Runia , Kirill Gavrilyuk , Cees G. M. Snoek , Arnold W. M. Smeulders

In this paper, we consider a coupled system of mixed hyperbolic-parabolic type which describes the Biot consolidation model in poro-elasticity. We establish a local Carleman estimate for Biot consilidation system. Using this estimate, we…

Analysis of PDEs · Mathematics 2016-12-21 Mourad Bellassoued , Bochra Riahi

Shape memory materials have gained considerable attention thanks to their ability to change physical properties when subjected to external stimuli such as temperature, pH, humidity, electromagnetic fields, etc. These materials are…

Numerical Analysis · Mathematics 2019-05-01 Innocent Niyonzima , Yang Jiao , Jacob Fish

In this work we analyze an optimized artificial fixed-stress iteration scheme for the numerical approximation of the Biot system modelling fluid flow in deformable porous media. The iteration is based on a prescribed constant artificial…

Numerical Analysis · Mathematics 2017-05-24 M. Bause , F. A. Radu , U. Köcher

A data-driven surrogate framework to accelerate particle-resolved modelling of quasi-dilute suspensions of rigid, non-spherical particles in Stokes flow is introduced. A regularized-Stokeslet boundary element method (BEM) is implemented to…

Fluid Dynamics · Physics 2025-12-17 Marco Laudato

Biophysical models describing complex, cellular phenomena typically include systems of nonlinear differential equations with many free parameters. While experimental measurements can fix some parameters, those describing internal cellular…

Computational Physics · Physics 2025-07-08 Joseph M. Marcinik , Martín A. Toderi , Dolores Bozovic

Deformable object manipulation remains a challenging task in robotics research. Conventional techniques for parameter inference and state estimation typically rely on a precise definition of the state space and its dynamics. While this is…

Robotics · Computer Science 2021-12-10 Rika Antonova , Jingyun Yang , Priya Sundaresan , Dieter Fox , Fabio Ramos , Jeannette Bohg

Machine learning force fields possess unprecedented potential in achieving both accuracy and efficiency in molecular simulations. Nevertheless, their application in organic systems is often hindered by structural collapse during simulation…

Computational Physics · Physics 2026-02-03 Junbao Hu , Dingyu Hou , Jian Jiang

Mathematical models and numerical simulations offer a non-invasive way to explore cardiovascular phenomena, providing access to quantities that cannot be measured directly. In this study, we start with a one-dimensional multiscale blood…

Machine Learning · Computer Science 2026-04-09 Giulia Bertaglia , Raffaella Fiamma Cabini

Despite rapid progress in the development of quantum algorithms in quantum computing as well as numerical simulation methods in classical computing for atomic and molecular applications, no systematic and comprehensive electronic structure…

A deep learning framework is developed for multiscale characterization of poroelastic media from full waveform data which is known as poroelastography. Special attention is paid to heterogeneous environments whose multiphase properties may…

Signal Processing · Electrical Eng. & Systems 2024-11-15 Yang Xu , Fatemeh Pourahmadian

It is well known that the number of particles should be scaled up to enable industrial scale simulation. The calculations are more computationally intensive when the motion of the surrounding fluid is considered. Besides the advances in…

Computational Physics · Physics 2014-07-28 Hao Zhang , F. Xavier Trias , Assensi Oliva , Dongmin Yang , Yuanqiang Tan , Shi Shu , Yong Sheng

In advancing discrete-based computational cancer models towards clinical applications, one faces the dilemma of how to deal with an ever growing amount of biomedical data that ought to be incorporated eventually in one form or another.…

Cell Behavior · Quantitative Biology 2008-06-26 Le Zhang , L. Leon Chen , Thomas S. Deisboeck

In this article a stochastic particle system approximation to the parametric sensitivity in the Smoluchowski coagulation equation is introduced. The parametric sensitivity is the derivative of the solution to the equation with respect to…

Probability · Mathematics 2016-09-08 I. Bailleul , P. L. W. Man , M. Kraft