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Causal inference in observational studies is notoriously difficult, due to the fact that the experimenter is not in charge of the treatment assignment mechanism. Many potential con- founding factors (PCFs) exist in such a scenario, and if…

Applications · Statistics 2015-09-15 Vadim von Brzeski , Matt Taddy , David Draper

Measuring conditional dependencies among the variables of a network is of great interest to many disciplines. This paper studies some shortcomings of the existing dependency measures in detecting direct causal influences or their lack of…

Machine Learning · Statistics 2017-06-05 Jalal Etesami , Kun Zhang , Negar Kiyavash

Epidemic models are always simplifications of real world epidemics. Which real world features to include, and which simplifications to make, depend both on the disease of interest and on the purpose of the modelling. In the present paper we…

Probability · Mathematics 2008-12-19 Tom Britton , David Lindenstrand

The review is devoted to analysis of mathematical models used for describing epidemic processes. A main focus is done on the models that are based on partial differential equations (PDEs), especially those that were developed and used for…

Populations and Evolution · Quantitative Biology 2024-03-01 Vasyl' Davydovych , Vasyl' Dutka , Roman Cherniha

In order to model an epidemic, different approaches can be adopted. Mainly, the deterministic approach and the stochastic one. Recently, a large amount of literature has been published using the two approaches. The aim of this paper is to…

Populations and Evolution · Quantitative Biology 2023-01-30 Mohamed Mehdaoui

Genomic imprinting and maternal effects are two epigenetic factors that have been increasingly explored for their roles in the etiology of complex diseases. This is part of a concerted effort to find the "missing heritability." Accordingly,…

Applications · Statistics 2013-04-18 Jingyuan Yang , Shili Lin

Human mobility, contact patterns, and their interplay are key aspects of our social behavior that shape the spread of infectious diseases across different regions. In the light of new evidence and data sets about these two elements,…

Physics and Society · Physics 2021-07-26 Wesley Cota , David Soriano-Paños , Alex Arenas , Silvio C. Ferreira , Jesús Gómez-Gardeñes

Epidemics are inherently stochastic, and stochastic models provide an appropriate way to describe and analyse such phenomena. Given temporal incidence data consisting of, for example, the number of new infections or removals in a given time…

Methodology · Statistics 2024-05-24 Sam A. Whitaker , Andrew Golightly , Colin S. Gillespie , Theodore Kypraios

Testing individuals for pathogens can affect the spread of epidemics. Understanding how individual-level processes of sampling and reporting test results can affect community- or population-level spread is a dynamical modeling question. The…

Populations and Evolution · Quantitative Biology 2021-07-20 Ali Gharouni , F. M. Abdelmalek , David J. D. Earn , Jonathan Dushoff , Benjamin M. Bolker

Compartmental epidemic models with dynamics that evolve over a graph network have gained considerable importance in recent years but analysis of these models is in general difficult due to their complexity. In this paper, we develop two…

Populations and Evolution · Quantitative Biology 2023-05-31 Sei Zhen Khong , Lanlan Su

Epidemiology characterizes the influence of causes to disease and health conditions of defined populations. Cohort studies are population-based studies involving usually large numbers of randomly selected individuals and comprising numerous…

Computer Vision and Pattern Recognition · Computer Science 2015-01-19 Bernhard Preim , Paul Klemm , Helwig Hauser , Katrin Hegenscheid , Steffen Oeltze , Klaus Toennies , Henry Völzke

Unmeasured confounding is a threat to causal inference in observational studies. In recent years, use of negative controls to mitigate unmeasured confounding has gained increasing recognition and popularity. Negative controls have a…

Methodology · Statistics 2019-09-05 Xu Shi , Wang Miao , Jennifer C. Nelson , Eric J. Tchetgen Tchetgen

The spatial structure of populations is a key element in the understanding of the large scale spreading of epidemics. Motivated by the recent empirical evidence on the heterogeneous properties of transportation and commuting patterns among…

Populations and Evolution · Quantitative Biology 2008-03-19 Vittoria Colizza , Alessandro Vespignani

Causal understanding is a fundamental goal of evidence-based medicine. When randomization is impossible, causal inference methods allow the estimation of treatment effects from retrospective analysis of observational data. However, such…

Machine Learning · Computer Science 2024-11-06 Samuel Lee , Zach Wood-Doughty

In this survey we discuss the recent causal panel data literature. This recent literature has focused on credibly estimating causal effects of binary interventions in settings with longitudinal data, emphasizing practical advice for…

Econometrics · Economics 2024-06-26 Dmitry Arkhangelsky , Guido Imbens

The increasing multiplicity of data sources offers exciting possibilities in estimating the effects of a treatment, intervention, or exposure, particularly if observational and experimental sources could be used simultaneously. Borrowing…

Methodology · Statistics 2020-03-24 Jeffrey A. Boatman , David M. Vock , Joseph S. Koopmeiners

Negative controls are increasingly used to evaluate the presence of potential unmeasured confounding in observational studies. Beyond the use of negative controls to detect the presence of residual confounding, proximal causal inference…

Methodology · Statistics 2024-06-06 Jiewen Liu , Chan Park , Kendrick Li , Eric J. Tchetgen Tchetgen

In the present work the spread of epidemic is studied over complex networks which are characterized by power law degree distribution of links and heterogeneous rate of disease transmission. The random allocation of epidemic transmission…

Physics and Society · Physics 2016-07-19 Vikram Sagar , Yi Zhao

In this work, we aim to formalize a novel scientific machine learning framework to reconstruct the hidden dynamics of the transmission rate, whose inaccurate extrapolation can significantly impair the quality of the epidemic forecasts, by…

Quantitative Methods · Quantitative Biology 2024-10-16 Giovanni Ziarelli , Stefano Pagani , Nicola Parolini , Francesco Regazzoni , Marco Verani

Aims: To re-introduce the Heckman model as a valid empirical technique in alcohol studies. Design: To estimate the determinants of problem drinking using a Heckman and a two-part estimation model. Psychological and neuro-scientific studies…

Econometrics · Economics 2023-07-03 Reka Sundaram-Stukel