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1.A goal of many research programs in biology is to extract meaningful insights from large, complex data sets. Researchers in Ecology, Evolution and Behavior (EEB) often grapple with long-term, observational data sets from which they…

Quantitative Methods · Quantitative Biology 2020-10-16 Zachary M. Laubach , Eleanor J. Murray , Kim L. Hoke , Rebecca J. Safran , Wei Perng

Individuals do not respond uniformly to treatments, events, or interventions. Sociologists routinely partition samples into subgroups to explore how the effects of treatments vary by covariates like race, gender, and socioeconomic status.…

Other Statistics · Statistics 2019-09-23 Jennie E. Brand , Jiahui Xu , Bernard Koch , Pablo Geraldo

Understanding the prevalence of key demographic and health indicators in small geographic areas and domains is of global interest, especially in low- and middle-income countries (LMICs), where vital registration data is sparse and household…

Applications · Statistics 2025-04-24 Qianyu Dong , Yunhan Wu , Zehang Richard Li , Jon Wakefield

The recent trend of integrating multi-source Chest X-Ray datasets to improve automated diagnostics raises concerns that models learn to exploit source-specific correlations to improve performance by recognizing the source domain of an image…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Srishti Gautam , Marina M. -C. Höhne , Stine Hansen , Robert Jenssen , Michael Kampffmeyer

Multivariate count time series models are an important tool for the analysis and prediction of infectious disease spread. We consider the endemic-epidemic framework, an autoregressive model class for infectious disease surveillance counts,…

Applications · Statistics 2020-03-16 Johannes Bracher , Leonhard Held

Causal inference analyses often use existing observational data, which in many cases has some clustering of individuals. In this paper we discuss propensity score weighting methods in a multilevel setting where within clusters individuals…

Applications · Statistics 2020-12-24 Youjin Lee , Trang Q. Nguyen , Elizabeth A. Stuart

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

When inferring the causal effect of one variable on another from correlational data, a common practice by professional researchers as well as lay decision makers is to control for some set of exogenous confounding variables. Choosing an…

Theoretical Economics · Economics 2023-05-31 Ran Spiegler

Hill's specificity criterion has been highly influential in biomedical and epidemiological research. However, it remains controversial and its application often relies on subjective and qualitative analysis without a comprehensive and…

Methodology · Statistics 2025-06-24 Wang Miao

Evidence-based knowledge of infectious disease burden, including prevalence, incidence, severity and transmission, in different population strata and locations, and possibly in real time, is crucial to the planning and evaluation of public…

Methodology · Statistics 2018-08-14 Daniela De Angelis , Anne M. Presanis

Airborne infection risk analysis is usually performed for enclosed spaces where susceptible individuals are exposed to infectious airborne respiratory droplets by inhalation. It is usually based on exponential, dose-response models of which…

Populations and Evolution · Quantitative Biology 2024-08-01 Yannis Drossinos , Nikolaos I. Stilianakis

Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…

Machine Learning · Computer Science 2023-08-08 Mutong Liu , Yang Liu , Jiming Liu

In the field of road safety, it is common to use responsibility analyses to assess the effect of a given factor on the risk of being responsible for an accident, among drivers involved in an accident only. Even if this design is now widely…

Methodology · Statistics 2018-10-16 Marine Dufournet , Emilie Lanoy , Jean-Louis Martin , Vivian Viallon

Nonlinear machine-learning models are increasingly used to discover causal relationships in time-series data, yet the interpretation of their outputs remains poorly understood. In particular, causal scores produced by regularized neural…

Machine Learning · Computer Science 2026-05-27 Valentina Kuskova , Dmitry Zaytsev , Michael Coppedge

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

Populations and Evolution · Quantitative Biology 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

We provide precise conditions for nonparametric identification of causal effects by high-frequency event study regressions, which have been used widely in the recent macroeconomics, financial economics and political economy literatures. The…

Econometrics · Economics 2025-07-24 Alessandro Casini , Adam McCloskey

Population size estimation based on the capture-recapture experiment is an interesting problem in various fields including epidemiology, criminology, demography, etc. In many real-life scenarios, there exists inherent heterogeneity among…

Methodology · Statistics 2023-08-01 Kiranmoy Chatterjee , Prajamitra Bhuyan

How should researchers analyze randomized experiments in which the main outcome is latent and measured in multiple ways but each measure contains some degree of error? We first identify a critical study-specific noncomparability problem in…

Econometrics · Economics 2026-01-13 Jiawei Fu , Donald P. Green

Forecasting the future course of epidemics has always been one of the main goals of epidemic modelling. This chapter reviews statistical methods to quantify the accuracy of epidemic forecasts. We distinguish point and probabilistic…

Methodology · Statistics 2019-12-19 Leonhard Held , Sebastian Meyer

We consider the estimation of measures of model performance in a target population when covariate and outcome data are available on a sample from some source population and covariate data, but not outcome data, are available on a simple…

Methodology · Statistics 2023-06-16 Jon A. Steingrimsson , Sarah E. Robertson , Issa J. Dahabreh