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Deep networks are successfully used as classification models yielding state-of-the-art results when trained on a large number of labeled samples. These models, however, are usually much less suited for semi-supervised problems because of…

Machine Learning · Computer Science 2018-12-05 Elad Hoffer , Nir Ailon

Data labeling is often the most challenging task when developing computational pathology models. Pathologist participation is necessary to generate accurate labels, and the limitations on pathologist time and demand for large, labeled…

Quantitative Methods · Quantitative Biology 2021-11-12 Lantian Zhang , Mohamed Amgad , Lee A. D. Cooper

In view of the fact that semi- and self-supervised learning share a fundamental principle, effectively modeling knowledge from unlabeled data, various semi-supervised semantic segmentation methods have integrated representative…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Yangyang Li , Xuanting Hao , Ronghua Shang , Licheng Jiao

Recent semi-supervised learning methods have shown to achieve comparable results to their supervised counterparts while using only a small portion of labels in image classification tasks thanks to their regularization strategies. In this…

Machine Learning · Computer Science 2020-09-25 Wei-Hong Li , Chuan-Sheng Foo , Hakan Bilen

In this paper, we propose a novel semi-supervised feature selection framework by mining correlations among multiple tasks and apply it to different multimedia applications. Instead of independently computing the importance of features for…

Machine Learning · Computer Science 2017-07-11 Xiaojun Chang , Yi Yang

As in many other scientific domains, we face a fundamental problem when using machine learning to identify proteins from mass spectrometry data: large ground truth datasets mapping inputs to correct outputs are extremely difficult to…

A significant issue in training deep neural networks to solve supervised learning tasks is the need for large numbers of labelled datapoints. The goal of semi-supervised learning is to leverage ubiquitous unlabelled data, together with…

Computer Vision and Pattern Recognition · Computer Science 2019-05-29 Chengxu Zhuang , Xuehao Ding , Divyanshu Murli , Daniel Yamins

For unsupervised pretraining, mask-reconstruction pretraining (MRP) approaches, e.g. MAE and data2vec, randomly mask input patches and then reconstruct the pixels or semantic features of these masked patches via an auto-encoder. Then for a…

Machine Learning · Computer Science 2023-02-14 Jiachun Pan , Pan Zhou , Shuicheng Yan

Semi-supervised algorithms aim to learn prediction functions from a small set of labeled observations and a large set of unlabeled observations. Because this framework is relevant in many applications, they have received a lot of interest…

Machine Learning · Computer Science 2025-02-17 Massih-Reza Amini , Vasilii Feofanov , Loic Pauletto , Lies Hadjadj , Emilie Devijver , Yury Maximov

Computer vision for animal behavior offers promising tools to aid research in ecology, cognition, and to support conservation efforts. Video camera traps allow for large-scale data collection, but high labeling costs remain a bottleneck to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Felix B. Mueller , Timo Lueddecke , Richard Vogg , Alexander S. Ecker

Pre-trained language models (PTLMs) acquire domain-independent linguistic knowledge through pre-training with massive textual resources. Additional pre-training is effective in adapting PTLMs to domains that are not well covered by the…

Computation and Language · Computer Science 2021-09-20 Kosuke Nishida , Kyosuke Nishida , Sen Yoshida

Semi-supervised learning leverages unlabeled data to enhance model performance, addressing the limitations of fully supervised approaches. Among its strategies, pseudo-supervision has proven highly effective, typically relying on one or…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Negin Ghamsarian , Sahar Nasirihaghighi , Klaus Schoeffmann , Raphael Sznitman

Surrogate models provide efficient alternatives to computationally demanding real world processes but often require large datasets for effective training. A promising solution to this limitation is the transfer of pre-trained surrogate…

Machine Learning · Computer Science 2025-05-14 Shuaiqun Pan , Diederick Vermetten , Manuel López-Ibáñez , Thomas Bäck , Hao Wang

The goal of protein representation learning is to extract knowledge from protein databases that can be applied to various protein-related downstream tasks. Although protein sequence, structure, and function are the three key modalities for…

Biomolecules · Quantitative Biology 2024-05-14 Eunji Ko , Seul Lee , Minseon Kim , Dongki Kim

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein functions. Recent sequence representation learning methods based on Protein Language Models (PLMs) excel in sequence-based…

Quantitative Methods · Quantitative Biology 2023-10-19 Zuobai Zhang , Chuanrui Wang , Minghao Xu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

Reducing the amount of labels required to train convolutional neural networks without performance degradation is key to effectively reduce human annotation efforts. We propose Reliable Label Bootstrapping (ReLaB), an unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2021-02-26 Paul Albert , Diego Ortego , Eric Arazo , Noel E. O'Connor , Kevin McGuinness

Deep learning has demonstrated its strengths in numerous binary analysis tasks, including function boundary detection, binary code search, function prototype inference, value set analysis, etc. When applying deep learning to binary analysis…

Machine Learning · Computer Science 2021-09-15 Xuezixiang Li , Qu Yu , Heng Yin

In recent years, protein-text models have gained significant attention for their potential in protein generation and understanding. Current approaches focus on integrating protein-related knowledge into large language models through…

Computation and Language · Computer Science 2025-11-11 Juntong Wu , Zijing Liu , He Cao , Hao Li , Bin Feng , Zishan Shu , Ke Yu , Li Yuan , Yu Li

Recent advances in generative modeling show that pretrained representations can improve generation as conditioning features or alignment targets. Motivated by this, we study protein representations for predicting structures beyond…

Biomolecules · Quantitative Biology 2026-05-27 Taewon Kim , Hyosoon Jang , Hyunjin Seo , Seonghwan Seo , Hyeongwoo Kim , Wonho Zhung , Mingyeong Shin , Wooyoun Kim , Sungsoo Ahn