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The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

We introduce here a fully automated convolutional neural network-based method for brain image processing to Detect Neurons in different brain Regions during Development (DeNeRD). Our method takes a developing mouse brain as input and i)…

Computer Vision and Pattern Recognition · Computer Science 2018-07-11 Asim Iqbal , Asfandyar Sheikh , Theofanis Karayannis

Identifying unusual brain activity is a crucial task in neuroscience research, as it aids in the early detection of brain disorders. It is common to represent brain networks as graphs, and researchers have developed various graph-based…

Machine Learning · Computer Science 2024-10-04 Sadaf Sadeghian , Xiaoxiao Li , Margo Seltzer

The graph Fourier transform (GFT) is an important tool for graph signal processing, with applications ranging from graph-based image processing to spectral clustering. However, unlike the discrete Fourier transform, the GFT typically does…

Signal Processing · Electrical Eng. & Systems 2019-10-02 Keng-Shih Lu , Antonio Ortega

Predicting cognition from neuroimaging data in healthy individuals offers insights into the neural mechanisms underlying cognitive abilities, with potential applications in precision medicine and early detection of neurological and…

Machine Learning · Computer Science 2025-07-29 Jagruti Patel , Mikkel Schöttner , Thomas A. W. Bolton , Patric Hagmann

Interactions between the brain and body are of fundamental importance for human behavior and health. Functional magnetic resonance imaging (fMRI) captures whole-brain activity noninvasively, and modeling how fMRI signals interact with…

Although rodent models are a predominant study model in neuroscience research, research investigating healthy rodent brain maturation remains limited. This motivates further study of normal brain maturation in rodents to exclude confounds…

Medical Physics · Physics 2023-09-28 Naila Rahman , Jake Hamilton , Kathy Xu , Arthur Brown , Corey A. Baron

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

Neurons and Cognition · Quantitative Biology 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu

The morphological fingerprint in the brain is capable of identifying the uniqueness of an individual. However, whether such individual patterns are present in perinatal brains, and which morphological attributes or cortical regions better…

Machine Learning · Computer Science 2023-11-28 Boyang Wang , Weihao Zheng , Ying Wang , Zhe Zhang , Yuchen Sheng , Minmin Wang

The vast majority of fMRI studies of task-related brain activity utilize common levels of task demands and analyses that rely on the central tendencies of the data. This approach does not take into account perceived difficulty nor regional…

Neurons and Cognition · Quantitative Biology 2021-10-14 Jason Steffener , Chris Habeck , Dylan Franklin , Meghan Lau , Yara Yakoub , Maryse Gad

This paper studies change-points in human brain functional connectivity (FC) and seeks patterns that are common across multiple subjects under identical external stimulus. FC relates to the similarity of fMRI responses across different…

Neurons and Cognition · Quantitative Biology 2020-03-05 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

It has been well established that Functional Connectomes (FCs), as estimated from functional MRI (fMRI) data, have an individual fingerprint that can be used to identify an individual from a population (subject-identification). Although…

We study how modularity of the human brain changes as children develop into adults. Theory suggests that modularity can enhance the response function of a networked system subject to changing external stimuli. Thus, greater cognitive…

Neurons and Cognition · Quantitative Biology 2015-01-29 Man Chen , Michael W. Deem

Foreseeing the brain evolution as a complex highly inter-connected system, widely modeled as a graph, is crucial for mapping dynamic interactions between different anatomical regions of interest (ROIs) in health and disease. Interestingly,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Zeynep Gurler , Ahmed Nebli , Islem Rekik

Graph neural networks (GNNs) have demonstrated success in learning representations of brain graphs derived from functional magnetic resonance imaging (fMRI) data. However, existing GNN methods assume brain graphs are static over time and…

Machine Learning · Computer Science 2023-07-11 Alexander Campbell , Antonio Giuliano Zippo , Luca Passamonti , Nicola Toschi , Pietro Lio

Addressing the question of visualising human mind could help us to find regions that are associated with observed cognition and responsible for expressing the elusive mental image, leading to a better understanding of cognitive function.…

Neurons and Cognition · Quantitative Biology 2021-02-11 Pan Wang , Rui Zhou , Shuo Wang , Ling Li , Wenjia Bai , Jialu Fan , Chunlin Li , Peter Childs , Yike Guo

Linear matrix factorizations (LMFs) such as independent component analysis (ICA), principal component analysis (PCA), and their extensions, have been widely used for finding relevant spatial maps in brain imaging data. The last step of an…

Quantitative Methods · Quantitative Biology 2021-10-14 Hyekyoung Lee , Hyejin Kang , Youngmin Huh , Hongyoon Choi , Dong Soo Lee

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…

Neurons and Cognition · Quantitative Biology 2025-08-26 Yanwen Wang , Xinglin Zhao , Yijin Song , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen