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Unstructured information in electronic health records provide an invaluable resource for medical research. To protect the confidentiality of patients and to conform to privacy regulations, de-identification methods automatically remove…

Computation and Language · Computer Science 2020-01-17 Jan Trienes , Dolf Trieschnigg , Christin Seifert , Djoerd Hiemstra

With the adoption of machine learning-based solutions in routine clinical practice, the need for reliable interpretability tools has become pressing. Shapley values provide local explanations. The method gained popularity in recent years.…

Methodology · Statistics 2023-06-27 Lucile Ter-Minassian , Sahra Ghalebikesabi , Karla Diaz-Ordaz , Chris Holmes

With continued advances in Geographic Information Systems and related computational technologies, statisticians are often required to analyze very large spatial datasets. This has generated substantial interest over the last decade, already…

Methodology · Statistics 2019-05-14 Lu Zhang , Abhirup Datta , Sudipto Banerjee

\textbf{Background:} Machine learning models trained on electronic health records (EHRs) often degrade across healthcare systems due to distributional shift. A fundamental but underexplored factor is diagnostic signal decay: variability in…

Machine Learning · Computer Science 2025-09-11 Jingya Cheng , Jiazi Tian , Federica Spoto , Alaleh Azhir , Daniel Mork , Hossein Estiri

The use of Deep Learning in the medical field is hindered by the lack of interpretability. Case-based interpretability strategies can provide intuitive explanations for deep learning models' decisions, thus, enhancing trust. However, the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 H. Montenegro , W. Silva , J. S. Cardoso

Visual discrimination of clinical tissue types remains challenging, with traditional RGB imaging providing limited contrast for such tasks. Hyperspectral imaging (HSI) is a promising technology providing rich spectral information that can…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Luis C. Garcia-Peraza-Herrera , Conor Horgan , Sebastien Ourselin , Michael Ebner , Tom Vercauteren

Model-based approaches for image reconstruction, analysis and interpretation have made significant progress over the last decades. Many of these approaches are based on either mathematical, physical or biological models. A challenge for…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Daniel Rueckert , Julia A. Schnabel

Segmenting deep brain structures from magnetic resonance images is important for patient diagnosis, surgical planning, and research. Most current state-of-the-art solutions follow a segmentation-by-registration approach, where subject MRIs…

Image and Video Processing · Electrical Eng. & Systems 2022-05-20 Mehri Baniasadi , Mikkel V. Petersen , Jorge Goncalves , Andreas Horn , Vanja Vlasov , Frank Hertel , Andreas Husch

Protected health information (PHI) de-identification is critical for enabling the safe reuse of clinical notes, yet evaluating and comparing PHI de-identification models typically depends on costly, small-scale expert annotations. We…

Artificial Intelligence · Computer Science 2025-11-19 Guanchen Wu , Zuhui Chen , Yuzhang Xie , Carl Yang

Training deep neural network (DNN) with noisy labels is practically challenging since inaccurate labels severely degrade the generalization ability of DNN. Previous efforts tend to handle part or full data in a unified denoising flow via…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Boshen Zhang , Yuxi Li , Yuanpeng Tu , Jinlong Peng , Yabiao Wang , Cunlin Wu , Yang Xiao , Cairong Zhao

Interpretability is often an essential requirement in medical imaging. Advanced deep learning methods are required to address this need for explainability and high performance. In this work, we investigate whether additional information…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Luisa Gallee , Meinrad Beer , Michael Goetz

De-identification of clinical text remains essential for secondary use of electronic health records (EHRs), yet public benchmarks such as i2b2 2006/2014 are over a decade old and lack the semantic and demographic diversity of modern…

Computation and Language · Computer Science 2026-05-06 Jose D. Posada , David Love , Somalee Datta , Priya Desai

Bayesian spatial modeling provides a flexible framework for whole-brain fMRI analysis by explicitly incorporating spatial dependencies, overcoming the limitations of traditional massive univariate approaches that lead to information waste.…

Methodology · Statistics 2025-11-18 Yuan Zhong , Gang Chen , Paul A. Taylor , Jian Kang

Deep neural networks are increasingly employed in high-stakes medical applications, despite their tendency for shortcut learning in the presence of spurious correlations, which can have potentially fatal consequences in practice. Whereas a…

Artificial Intelligence · Computer Science 2025-07-30 Frederik Pahde , Thomas Wiegand , Sebastian Lapuschkin , Wojciech Samek

Modeling policies for sequential clinical decision-making based on observational data is useful for describing treatment practices, standardizing frequent patterns in treatment, and evaluating alternative policies. For each task, it is…

Machine Learning · Computer Science 2024-12-12 Anton Matsson , Lena Stempfle , Yaochen Rao , Zachary R. Margolin , Heather J. Litman , Fredrik D. Johansson

The rapid expansion of AI in healthcare has led to a surge in medical data generation and storage, boosting medical AI development. However, fears of unauthorized use, like training commercial AI models, hinder researchers from sharing…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Weixiang Sun , Yixin Liu , Zhiling Yan , Kaidi Xu , Lichao Sun

Interactive segmentation is a promising strategy for building robust, generalisable algorithms for volumetric medical image segmentation. However, inconsistent and clinically unrealistic evaluation hinders fair comparison and misrepresents…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Parhom Esmaeili , Virginia Fernandez , Pedro Borges , Eli Gibson , Sebastien Ourselin , M. Jorge Cardoso

Scribble annotations significantly reduce the cost and labor required for dense labeling in large medical datasets with complex anatomical structures. However, current scribble-supervised learning methods are limited in their ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Luyi Qiu , Tristan Till , Xiaobao Guo , Adams Wai-Kin Kong

Large-scale radiology data are critical for developing robust medical AI systems. However, sharing such data across hospitals remains heavily constrained by privacy concerns. Existing de-identification research in radiology mainly focus on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Chenhao Liu , Zelin Wen , Yan Tong , Junjie Zhu , Xinyu Tian , Yuchi Liu , Ashu Gupta , Syed M. S. Islam , Tom Gedeon , Yue Yao

AI algorithms have become valuable in aiding professionals in healthcare. The increasing confidence obtained by these models is helpful in critical decision demands. In clinical dermatology, classification models can detect malignant…