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The cytoskeleton, consisting of biopolymer filaments, molecular motors, and passive crosslinking proteins, provides the internal structure of cells that facilitate movement, growth, and cell division. Understanding the microscopic…

Soft Condensed Matter · Physics 2024-05-09 Zihan Zhang , Adam R. Lamson , Robert Blackwell

Trajectory optimization is becoming increasingly powerful in addressing motion planning problems of underactuated robotic systems. Numerous prior studies solve such a class of large non-convex optimal control problems in a hierarchical…

Robotics · Computer Science 2020-03-19 Ziyi Zhou , Ye Zhao

Reinforcement learning methods as a promising technique have achieved superior results in the motion planning of free-floating space robots. However, due to the increase in planning dimension and the intensification of system dynamics…

Robotics · Computer Science 2022-09-07 Yuxue Cao , Shengjie Wang , Xiang Zheng , Wenke Ma , Xinru Xie , Lei Liu

Recent works on click-based interactive segmentation have demonstrated state-of-the-art results by using various inference-time optimization schemes. These methods are considerably more computationally expensive compared to feedforward…

Computer Vision and Pattern Recognition · Computer Science 2021-02-15 Konstantin Sofiiuk , Ilia A. Petrov , Anton Konushin

Generating motions for robots interacting with objects of various shapes is a complex challenge, further complicated by the robot geometry and multiple desired behaviors. While current robot programming tools (such as inverse kinematics,…

Robotics · Computer Science 2025-06-19 Xuemin Chi , Hakan Girgin , Tobias Löw , Yangyang Xie , Teng Xue , Jihao Huang , Cheng Hu , Zhitao Liu , Sylvain Calinon

Model free reinforcement learning suffers from the high sampling complexity inherent to robotic manipulation or locomotion tasks. Most successful approaches typically use random sampling strategies which leads to slow policy convergence. In…

Robotics · Computer Science 2019-08-13 Miroslav Bogdanovic , Ludovic Righetti

When described by a low-dimensional reaction coordinate, the rates of protein folding are determined by a subtle interplay between free-energy barriers and friction. While it is commonplace to extract free-energy profiles from molecular…

Soft Condensed Matter · Physics 2022-10-24 Benjamin A. Dalton , Cihan Ayaz , Lucas Tepper , Roland R. Netz

Computing stabilizing and optimal control actions for legged locomotion in real time is difficult due to the nonlinear, hybrid, and high dimensional nature of these robots. The hybrid nature of the system introduces a combination of…

Robotics · Computer Science 2025-08-26 Zachary Olkin , Aaron D. Ames

This work adds on to the on-going efforts to provide more autonomy to space robots. Here the concept of programming by demonstration or imitation learning is used for trajectory planning of manipulators mounted on small spacecraft. For…

Robotics · Computer Science 2020-08-11 RB Ashith Shyam , Zhou Hao , Umberto Montanaro , Gerhard Neumann

In recent years, deep learning techniques have made significant strides in molecular generation for specific targets, driving advancements in drug discovery. However, existing molecular generation methods present significant limitations:…

Machine Learning · Computer Science 2025-03-12 Taojie Kuang , Qianli Ma , Athanasios V. Vasilakos , Yu Wang , Qiang , Cheng , Zhixiang Ren

Using movement primitive libraries is an effective means to enable robots to solve more complex tasks. In order to build these movement libraries, current algorithms require a prior segmentation of the demonstration trajectories. A…

Machine Learning · Statistics 2020-03-03 Maximilian Sieb , Matthias Schultheis , Sebastian Szelag , Rudolf Lioutikov , Jan Peters

Motion retargeting from a human demonstration to a robot is an effective way to reduce the professional requirements and workload of robot programming, but faces the challenges resulting from the differences between humans and robots.…

Robotics · Computer Science 2022-03-01 Haodong Zhang , Weijie Li , Jiangpin Liu , Zexi Chen , Yuxiang Cui , Yue Wang , Rong Xiong

Many aspects of the study of protein folding and dynamics have been affected by the recent advances in machine learning. Methods for the prediction of protein structures from their sequences are now heavily based on machine learning tools.…

Biological Physics · Physics 2019-11-25 Frank Noé , Gianni De Fabritiis , Cecilia Clementi

Significant progress in computer hardware and software have enabled molecular dynamics (MD) simulations to model complex biological phenomena such as protein folding. However, enabling MD simulations to access biologically relevant…

Biomolecules · Quantitative Biology 2019-08-02 Heng Ma , Debsindhu Bhowmik , Hyungro Lee , Matteo Turilli , Michael T. Young , Shantenu Jha , Arvind Ramanathan

Deep generative models have recently been proposed for sampling protein conformations from the Boltzmann distribution, as an alternative to often prohibitively expensive Molecular Dynamics simulations. However, current state-of-the-art…

Biomolecules · Quantitative Biology 2025-11-13 Nicolas Wolf , Leif Seute , Vsevolod Viliuga , Simon Wagner , Jan Stühmer , Frauke Gräter

Robust parameter estimation is a crucial task in several 3D computer vision pipelines such as Structure from Motion (SfM). State-of-the-art algorithms for robust estimation, however, still suffer from difficulties in converging to…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Huu Le , Christopher Zach

Feature tracking is a fundamental problem in computer vision, with applications in many computer vision tasks, such as visual SLAM and action recognition. This paper introduces a novel multi-body feature tracker that exploits a multi-body…

Computer Vision and Pattern Recognition · Computer Science 2016-03-16 Pan Ji , Hongdong Li , Mathieu Salzmann , Yiran Zhong

Sampling based methods are widely used for robotic motion planning. Traditionally, these samples are drawn from probabilistic ( or deterministic ) distributions to cover the state space uniformly. Despite being probabilistically complete,…

Robotics · Computer Science 2020-06-09 Rajat Kumar Jenamani , Rahul Kumar , Parth Mall , Kushal Kedia

To generate reliable motion for legged robots through trajectory optimization, it is crucial to simultaneously compute the robot's path and contact sequence, as well as accurately consider the dynamics in the problem formulation. In this…

Robotics · Computer Science 2025-10-29 Sangmin Kim , Hajun Kim , Gijeong Kim , Min-Gyu Kim , Hae-Won Park

This paper presents a novel approach that combines the advantages of both model-based and learning-based frameworks to achieve robust locomotion. The residual modules are integrated with each corresponding part of the model-based framework,…

Robotics · Computer Science 2025-07-25 Min-Gyu Kim , Dongyun Kang , Hajun Kim , Hae-Won Park
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