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We study a phenomenological electropermeabilization model in a periodic medium representing biological tissue. Starting from a cell-level model describing the electric potential and the degree of porosity, we perform dimension analysis to…

Analysis of PDEs · Mathematics 2026-02-03 Tobias Gebäck , Ioanna Motschan-Armen , Irina Pettersson

In canonical models of Micro-Electro Mechanical Systems (MEMS), an event called touch- down whereby the electrical components of the device come into contact, is characterized by a blow up in the governing equations and a non-physical…

Analysis of PDEs · Mathematics 2013-10-02 A. E. Lindsay , J. Lega , K. B. Glasner

We describe a system of stochastic differential equations (SDEs) which model the interaction between processive molecular motors, such as kinesin and dynein, and the biomolecular cargo they tow as part of microtubule-based intracellular…

Probability · Mathematics 2011-11-04 Scott A. McKinley , Avanti Athreya , John Fricks , Peter R. Kramer

In eukaryotic cell chemotaxis, cells extend and retract transient actin-driven protrusions at their membrane that facilitate both the detection of external chemical gradients and directional movement via the formation of focal adhesions…

Cell Behavior · Quantitative Biology 2025-09-25 Samuel W. S. Johnson , Maddy Parsons , Ruth E. Baker , Philip K. Maini

Bacteria typically reside in heterogeneous environments with various chemogradients where motile cells can gain an advantage over non-motile cells. Since motility is energetically costly, cells must optimize their swimming speed and…

Populations and Evolution · Quantitative Biology 2020-05-05 Gurdip Uppal , Weiyi Hu , Dervis Can Vural

We use partial differential equations (PDEs) to describe physical systems. In general, these equations include evolution and constraint equations. One method used to find solutions to these equations is the Free-evolution approach, which…

Analysis of PDEs · Mathematics 2022-10-05 J. Fernando Abalos

Microorganisms such as bacteria are active matters which consume chemical energy and generate their unique run-and-tumble motion. A swarm of such microorganisms provide a nonequilibrium active environment whose noise characteristics are…

Statistical Mechanics · Physics 2020-09-16 Jae Sung Lee , Jong-Min Park , Hyunggyu Park

Metagenomics has revealed hundreds of bacterial species in almost all microbiota. In a few well-studied cases, bacterial communities have been observed to coordinate their metabolic fluxes. In principle, bacteria can divide tasks to reap…

Populations and Evolution · Quantitative Biology 2016-04-12 Thibaud Taillefumier , Anna Posfai , Yigal Meir , Ned S. Wingreen

The skin microbiome plays an important role in the maintenance of a healthy skin. It is an ecosystem, composed of several species, competing for resources and interacting with the skin cells. Imbalance in the cutaneous microbiome, also…

Quantitative Methods · Quantitative Biology 2022-06-22 Eléa Thibault Greugny , Georgios N Stamatas , François Fages

The goal of magnetic fusion research is to extract the power released by fusion reactions and carried by the product of these reactions, liberated at energies of the order of a few MeV. The feasibility of fusion energy production relies on…

Plasma Physics · Physics 2009-12-15 Christine Nguyen

Resource-based competition between microorganisms species in continuous culture has been studied extensively both experimentally and theoretically, mostly for bacteria through Monod and and Contois "constant yield" models, or for…

Optimization and Control · Mathematics 2012-08-09 Pierre Masci , Frédéric Grognard , Eric Benoît , Olivier Bernard

We present a model for continuous cell culture coupling intra-cellular metabolism to extracellular variables describing the state of the bioreactor, taking into account the growth capacity of the cell and the impact of toxic byproduct…

Molecular Networks · Quantitative Biology 2017-11-21 Jorge Fernandez-de-Cossio-Diaz , Kalet León , Roberto Mulet

A mathematical model involving a syntrophic relationship between two populations of bacteria in a continuous culture is proposed. A detailed qualitative analysis is carried out. The local and global stability analysis of the equilibria are…

Dynamical Systems · Mathematics 2011-08-01 Tewfik Sari , Miled El Hajji , Jérôme Harmand

The question of what guides lineage segregation is central to development, where cellular differentiation leads to segregated cell populations destined for specialized functions. Here, using optical tweezers measurements of mouse embryonic…

Well-posedness of a free boundary problem for electrostatic microelectromechanical systems (MEMS) is investigated when nonlinear bending effects are taken into account. The model describes the evolution of the deflection of an electrically…

Analysis of PDEs · Mathematics 2014-09-26 Philippe Laurencot , Christoph Walker

Electrochemically mediated selective adsorption is an emerging electrosorption technique that utilizes Faradaically enhanced redox active electrodes, which can adsorb ions not only electrostatically, but also electrochemically. The superb…

Chemical Physics · Physics 2021-01-05 Fan He , Martin Z. Bazant , T. Alan Hatton

Classical molecular dynamics simulations have recently become a standard tool for the study of electrochemical systems. State-of-the-art approaches represent the electrodes as perfect conductors, modelling their responses to the charge…

Cell competition in multicellular organisms has been shown to play a critical role during the development of organisms, cancer progression, and in the establishment and maintenance of tissue homeostasis. Various mechanisms of cell…

Biological Physics · Physics 2025-10-27 Hossein Nemati , Saskia Jacoba Elisabeth Suijkerbuijk , Joost de Graaf

We study the existence of weak solutions for a model of cell invasion into the extracellular matrix (ECM), which consists of a non-linear partial differential equation for the density of cells, coupled with an ordinary differential equation…

Analysis of PDEs · Mathematics 2025-01-20 Rebecca M. Crossley , Jan-Frederik Pietschmann , Markus Schmidtchen

This paper is concerned with a mathematical model of competition for resource where species consume noninteracting resources. This system of differential equations is formally obtained by renormalizing the MacArthur's competition model at…

Dynamical Systems · Mathematics 2020-07-27 Wenli Cai , Hailiang Liu