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The development of X-ray Free Electron Lasers (XFELs) has opened numerous opportunities to probe atomic structure and ultrafast dynamics of various materials. Single Particle Imaging (SPI) with XFELs enables the investigation of biological…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Zhantao Chen , Cong Wang , Mingye Gao , Chun Hong Yoon , Jana B. Thayer , Joshua J. Turner

The European X-ray Free Electron Laser (XFEL) will deliver 27000 fully coherent, high brilliance X-ray pulses per second each with a duration below 100 fs. This will allow the recording of diffraction patterns of single molecules and the…

Instrumentation and Detectors · Physics 2015-06-03 J. Schwandt , E. Fretwurst , R. Klanner , I. Pintilie , J. Zhang

Numerical simulation codes are basic tools for designing Free Electron Lasers (FELs). This paper describes a numerical method for the time-dependent, three-dimensional simulation of the free electron laser (FEL) using a rectangular…

Accelerator Physics · Physics 2020-04-22 Weiwei Li , Heting Li , Zhigang He , Qika Jia , Lin Wang , Yalin Lu

We propose and analyze a novel regenerative amplifier free electron laser (FEL) to produce fully coherent x-ray pulses. The method makes use of narrow-bandwidth Bragg crystals to form an x-ray feedback loop around a relatively short…

Accelerator Physics · Physics 2009-11-11 Zhirong Huang , Ronald D. Ruth

Resonant scattering of energetic protons off magnetic irregularities is the main process in cosmic ray diffusion. The typical theoretical description uses Alfven waves in the low frequency limit. We demonstrate that the usage of…

Solar and Stellar Astrophysics · Physics 2014-05-09 Cedric Schreiner , Felix Spanier

SMILEI is a collaborative, open-source, object-oriented (C++) particle-in-cell code. To benefit from the latest advances in high-performance computing (HPC), SMILEI is co-developed by both physicists and HPC experts. The code's structures,…

The solvation free energy (SFE) of molecules and ions is a fundamental property governing their solvation behavior and solubility. Molecular simulations offer a route to compute SFEs using alchemical free energy methods, such as…

Chemical Physics · Physics 2026-04-21 Junting Yu , Shuo-Hui Li , Ding Pan

Direct studies of intense laser-solid interactions is still of great challenges, because of the many coupled physical mechanisms, such as direct laser heating, ionization dynamics, collision among charged particles, and electrostatic or…

Plasma Physics · Physics 2017-03-16 D. Wu , X. T. He , W. Yu , S. Fritzsche

Entropic measures like Shannon entropy (SE), its quantum mechanical analogue von Neumann entropy, and Kullback-Leibler divergence (KL) are key components in many tools used in physics, information theory, machine learning (ML) and quantum…

Machine Learning · Computer Science 2026-04-27 Illia Horenko , Davide Bassetti , Lukáš Pospíšil

Active Learning (AL) reduces annotation costs in medical imaging by selecting only the most informative samples for labeling, but suffers from cold-start when labeled data are scarce. Vision-Language Models (VLMs) address the cold-start…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Zhuofan Xie , Zishan Lin , Jinliang Lin , Jie Qi , Shaohua Hong , Shuo Li

Free-electron lasers (FELs) generate the brightest coherent X-ray pulses available, enabling atomic-resolution and femtosecond-timescale studies across physics, chemistry, and biology. Realising their full potential at extreme peak powers…

Accelerator Physics · Physics 2026-03-17 Çağrı Erciyes , Christoph H. Keitel , Matteo Tamburini

X-ray free-electron lasers (FELs) are promising tools for structural determination of macromolecules via coherent x-ray scattering. During ultrashort and ultraintense x-ray pulses with an atomic scale wavelength, samples are subject to…

Atomic Physics · Physics 2011-10-18 Sang-Kil Son , Linda Young , Robin Santra

X-ray free-electron lasers (XFELs) produce X-ray pulses with high brilliance and short pulse duration. These properties enable structural investigations of biomolecular nanocrystals, and they allow resolving the dynamics of biomolecules…

Chemical Physics · Physics 2022-08-05 Leonie Chatzimagas , Jochen S. Hub

X-ray Free Electron Lasers (XFEL) are revolutionary photons sources, whose ultrashort, brilliant pulses are expected to allow single molecule diffraction experiments providing structural information on the atomic length scale. This ultimate…

Optics · Physics 2015-05-20 Andrea Fratalocchi , Giancarlo Ruocco

The potential for laser-produced plasmas to yield fundamental insights into high energy density physics (HEDP) and deliver other useful applications can sometimes be frustrated by uncertainties in modeling the properties and expansion of…

Plasma Physics · Physics 2013-06-10 Chris Orban , Milad Fatenejad , Sugreev Chawla , Scott C. Wilks , Donald Q. Lamb

We use particle-in-cell (PIC) simulations and simple analytic models to investigate the laser-plasma interaction known as ponderomotive steepening. When normally incident laser light reflects at the critical surface of a plasma, the…

Simple formulas for optimization of VUV and X-ray SASE FELs are presented. The FEL gain length and the optimal beta-function are explicitly expressed in terms of the electron beam and undulator parameters. The FEL saturation length is…

Accelerator Physics · Physics 2009-11-10 E. L. Saldin , E. A. Schneidmiller , M. V. Yurkov

We describe a free-electron laser (FEL) in the Self Amplified Spontaneous Emission (SASE) regime quantizing the electron motion and taking into account propagation effects. We demonstrate quantum purification of the SASE spectrum, i.e., in…

Accelerator Physics · Physics 2009-11-11 R. Bonifacio , N. Piovella , G. R. M. Robb

Numerical heating in particle-in-cell (PIC) codes currently precludes the accurate simulation of cold, relativistic plasma over long periods, severely limiting their applications in astrophysical environments. We present a spatially…

The first experimental data from single-particle scattering experiments from free electron lasers (FELs) are now becoming available. The first such experiments are being performed on relatively large objects such as viruses, which produce…

Biomolecules · Quantitative Biology 2015-05-28 Dilano Saldin , Hin-Cheuck Poon , Peter Schwander , Miraj Uddin , Marius Schmidt