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We study the steady state of an assembly of microtubules in a confined volume, analogous to the situation inside a cell where the cell boundary forms a natural barrier to growth. We show that the dynamical equations for growing and…

Subcellular Processes · Quantitative Biology 2012-08-27 Bindu S. Govindan , William. B. Spillman,

The persistent motion of bacteria produces clusters with a stationary cluster size distribution (CSD). Here we develop a minimal model for bacteria in a narrow channel to assess the relative importance of motility diversity (i.e.…

Soft Condensed Matter · Physics 2020-11-19 Pablo de Castro , Saulo Diles , Rodrigo Soto , Peter Sollich

Protein distributions measured under a broad set of conditions in bacteria and yeast were shown to exhibit a common skewed shape, with variances depending quadratically on means. For bacteria these properties were reproduced by temporal…

Biological Physics · Physics 2015-10-28 Naama Brenner , C. M. Newman , Dino Osmanovic , Yitzhak Rabin , Hanna Salman , D. L. Stein

Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

Quantitative Methods · Quantitative Biology 2009-11-13 Carlos Escudero

Growth rate is one of the most important and most complex phenotypic characteristics of unicellular microorganisms, which determines the genetic mutations that dominate at the population level, and ultimately whether the population will…

Cell Behavior · Quantitative Biology 2019-01-23 Thomas P. Wytock , Adilson E. Motter

A variety of living and non-living systems exhibit collective motion. From swarm robotics to bacterial swarms, and tissue wound healing to human crowds, examples of collective motion are highly diverse but all of them share the common…

Biological Physics · Physics 2023-07-12 Jonathan E. Dawson , Abdul N. Malmi-Kakkada

We study the migration of chemotactic wild-type Escherichia coli populations in semisolid (soft) agar in the concentration range C = 0.15-0.5% (w/v). For C < 0.35%, expanding bacterial colonies display characteristic chemotactic rings. At C…

Soft Condensed Matter · Physics 2011-08-09 O. A. Croze , G. P. Ferguson , M. E. Cates , W. C. K. Poon

We consider two division models for structured cell populations, where cells can grow, age and divide. These models have been introduced in the literature under the denomination of `mitosis' and `adder' models. In the recent years, there…

Granular mixtures frequently segregate by grain size along the axis of partially-filled, horizontal, rotating tubes. When segregation approaches saturation at the surface, a well-defined pattern of bands with wavelength $\lambda$ emerges.…

Soft Condensed Matter · Physics 2007-05-23 Christopher R. J. Charles , Zeina S. Khan , Stephen W. Morris

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

Analysis of PDEs · Mathematics 2013-06-11 Martin Kohlmann

We consider a population organised hierarchically with respect to size in such a way that the growth rate of each individual depends only on the presence of larger individuals. As a concrete example one might think of a forest, in which the…

Populations and Evolution · Quantitative Biology 2024-04-23 Carles Barril , Àngel Calsina , Odo Diekmann , József Z. Farkas

We systematically study the boundaries of one-dimensional, 2-color cellular automata depending on 4 cells, begun from simple initial conditions. We determine the exact growth rates of the boundaries that appear to be reducible. Morphic…

Cellular Automata and Lattice Gases · Physics 2015-03-13 Charles D. Brummitt , Eric Rowland

We consider an age-size structured cell population model based on the cell cycle length. The model is described by a first order partial differential equation with initial-boundary conditions. Using the theory of semigroups of positive…

Analysis of PDEs · Mathematics 2022-06-15 Katarzyna Pichór , Ryszard Rudnicki

Centrifugation of biological matter in density gradient solutions is a standard method for separating cell types or components. It is also used to separate red blood cells (RBCs) by age, as they lose water and become denser over their…

Soft Condensed Matter · Physics 2026-02-09 Felix Maurer , Camila Romero , Nikolas Lerch , Thomas John , Lars Kaestner , Christian Wagner , Alexis Darras

We quantify the amount of regulation required to control growth in living cells by a Maximum Entropy approach to the space of underlying metabolic states described by genome-scale models. Results obtained for E. coli and human cells are…

Molecular Networks · Quantitative Biology 2017-07-19 Daniele De Martino , Fabrizio Capuani , Andrea De Martino

The growth of a crystal is usually determined by its surface. Many factors influence the growth dynamics. Energy barriers associated with the presence of steps most often decide about the emerging pattern. The height and type of…

Materials Science · Physics 2023-12-08 Marta Anna Chabowska , Magdalena A. Załuska-Kotur

We model the growth of a cell population using a piecewise deterministic Markov branching tree. In this model, each cell splits into two offspring at a division rate $B(x)$, which depends on its size $x$. The size of each cell increases…

Probability · Mathematics 2024-09-06 Nathalie Krell

We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confinement while interacting sterically, mimicking cells in early…

Soft Condensed Matter · Physics 2024-10-01 Samantha R. Lish , Lukas Hupe , Ramin Golestanian , Philip Bittihn

Using in-situ synchrotron tomography, we investigate the coarsening dynamics of barium borosilicate melts during phase separation. The 3-D geometry of the two interconnected phases is determined thanks to image processing. We observe a…

It has recently been observed that the SIR distributions of a variety of cellular network models and transmission techniques look very similar in shape. As a result, they are well approximated by a simple horizontal shift (or gain) of the…

Information Theory · Computer Science 2015-11-30 Radha K. Ganti , Martin Haenggi